to add to this, the registration it uses is performed on the whole head, so skull/skin/dura/fat/neck is included, which make the registration less susceptible to mis-registration due to lesions/atrophy/resection.
n. On Wed, 2013-05-08 at 15:15 -0400, Douglas N Greve wrote: > I don't know, I don't think the test has ever been done. It probably > depends upon how good the talairach registration is. > doug > > > On 05/08/2013 03:12 PM, Mohammed Goryawala wrote: > > Hi, > > > > A follow up question pertaining to this issue for me is how good is > > the measure of the ICV when dealing with subjects having prior > > resections or significant atrophy. I am using FreeSurfer v5.1. > > > > Thank you > > M. Goryawala > > Post-Doctoral Associate > > Florida International University > > Miami, FL > > > > > > On Wed, May 8, 2013 at 11:53 AM, Alejandra Infante > > <infante.alejandr...@gmail.com <mailto:infante.alejandr...@gmail.com>> > > wrote: > > > > Thank you! > > > > Sent from my iPhone > > > > On May 8, 2013, at 8:17 AM, Douglas N Greve > > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote: > > > > > > > > Hi Alejandra, I don't work with children, so I'll let someone > > else (Lilla? Rudolph?) answer. > > > doug > > > ps. Please remember to copy the list on responses. Thanks! > > > > > > On 05/08/2013 01:19 AM, Alejandra Infante wrote: > > >> Thank you! I might have asked this at the training, but I am > > still not clear on whether the estimated ICV (from freesurfer) is > > reliable if your population of interest are children? Or would you > > recommend manual edits (when needed) after checking the quality of > > the talairach registration file using tkregister2 --s subjid > > --fstal --surfs? > > >> > > >> > > >> On Tue, May 7, 2013 at 7:52 PM, Douglas Greve > > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu> > > <mailto:gr...@nmr.mgh.harvard.edu > > <mailto:gr...@nmr.mgh.harvard.edu>>> wrote: > > >> > > >> > > >> It is neither:) See > > http://surfer.nmr.mgh.harvard.edu/fswiki/eTIV > > >> and/or Buckner et al. (2004) NeuroImage > > >> <https://surfer.nmr.mgh.harvard.edu/fswiki/NeuroImage> > > 23:724-738. > > >> > > >> "Basically, total intracranial volume is found to correlate with > > >> the determinant of the transform matrix used to align an image > > >> with an atlas. The work demonstrates that a one-parameter > > scaling > > >> factor provides a reasonable TIV estimation. This method uses an > > >> atlas based spatial normalization procedure, and requires > > that the > > >> *talairach.xfm* is correct. " > > >> > > >> This performs the talairach registration for a subject. Then, > > >> based only on the numbers in the matrix, it estimates the ICV > > >> based on subjects that had similar matrices. > > >> > > >> doug > > >> > > >> > > >> > > >> On 5/7/13 9:42 PM, Alejandra Infante wrote: > > >>> Hi, > > >>> I understand that ICV is an estimated measure based on a > > standard > > >>> talairach transformation; however, I want to know how > > freesurfer > > >>> is defining intracranial volume (i.e., is this a representation > > >>> of everything within the cranium as the name implies or is > > it an > > >>> estimate of total brain volume, which would not include space > > >>> between skull and dura)?. We are using fs vesion 5.1 > > >>> > > >>> > > >>> -- M. Alejandra Infante > > >>> Doctoral Student > > >>> SDSU/UCSD Joint Doctoral Program in Clinical Psychology > > >>> Phone: (858) 449-2950 <tel:%28858%29%20449-2950> > > <tel:%28858%29%20449-2950> > > >>> E-Mail: infante.alejandr...@gmail.com > > <mailto:infante.alejandr...@gmail.com> > > >>> <mailto:infante.alejandr...@gmail.com > > <mailto:infante.alejandr...@gmail.com>> > > >>> > > >>> > > >>> > > >>> _______________________________________________ > > >>> Freesurfer mailing list > > >>> Freesurfer@nmr.mgh.harvard.edu > > <mailto:Freesurfer@nmr.mgh.harvard.edu> > > <mailto:Freesurfer@nmr.mgh.harvard.edu > > <mailto:Freesurfer@nmr.mgh.harvard.edu>> > > >>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > >> > > >> > > >> _______________________________________________ > > >> Freesurfer mailing list > > >> Freesurfer@nmr.mgh.harvard.edu > > <mailto:Freesurfer@nmr.mgh.harvard.edu> > > <mailto:Freesurfer@nmr.mgh.harvard.edu > > <mailto:Freesurfer@nmr.mgh.harvard.edu>> > > >> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > >> > > >> > > >> The information in this e-mail is intended only for the > > person to > > >> whom it is > > >> addressed. If you believe this e-mail was sent to you in > > error and > > >> the e-mail > > >> contains patient information, please contact the Partners > > >> Compliance HelpLine at > > >> http://www.partners.org/complianceline . If the e-mail was sent to > > >> you in error > > >> but does not contain patient information, please contact the > > >> sender and properly > > >> dispose of the e-mail. > > >> > > >> > > >> > > >> > > >> -- > > >> M. Alejandra Infante > > >> Doctoral Student > > >> SDSU/UCSD Joint Doctoral Program in Clinical Psychology > > >> Phone: (858) 449-2950 <tel:%28858%29%20449-2950> > > >> E-Mail: infante.alejandr...@gmail.com > > <mailto:infante.alejandr...@gmail.com> > > <mailto:infante.alejandr...@gmail.com > > <mailto:infante.alejandr...@gmail.com>> > > > > > > -- > > > Douglas N. Greve, Ph.D. > > > MGH-NMR Center > > > gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu> > > > Phone Number: 617-724-2358 <tel:617-724-2358> > > > Fax: 617-726-7422 <tel:617-726-7422> > > > > > > Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting > > <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting> > > > FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 > > > www.nmr.mgh.harvard.edu/facility/filedrop/index.html > > <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html> > > > Outgoing: > > ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ > > > > > > > _______________________________________________ > > Freesurfer mailing list > > Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu> > > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > > > > > > > > _______________________________________________ > > Freesurfer mailing list > > Freesurfer@nmr.mgh.harvard.edu > > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
