Hi Alejandra, I don't work with children, so I'll let someone else (Lilla? Rudolph?) answer. doug ps. Please remember to copy the list on responses. Thanks!
On 05/08/2013 01:19 AM, Alejandra Infante wrote: > Thank you! I might have asked this at the training, but I am still not > clear on whether the estimated ICV (from freesurfer) is reliable if > your population of interest are children? Or would you recommend > manual edits (when needed) after checking the quality of the talairach > registration file using tkregister2 --s subjid --fstal --surfs? > > > On Tue, May 7, 2013 at 7:52 PM, Douglas Greve > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote: > > > It is neither:) See http://surfer.nmr.mgh.harvard.edu/fswiki/eTIV > and/or Buckner et al. (2004) NeuroImage > <https://surfer.nmr.mgh.harvard.edu/fswiki/NeuroImage> 23:724-738. > > "Basically, total intracranial volume is found to correlate with > the determinant of the transform matrix used to align an image > with an atlas. The work demonstrates that a one-parameter scaling > factor provides a reasonable TIV estimation. This method uses an > atlas based spatial normalization procedure, and requires that the > *talairach.xfm* is correct. " > > This performs the talairach registration for a subject. Then, > based only on the numbers in the matrix, it estimates the ICV > based on subjects that had similar matrices. > > doug > > > > On 5/7/13 9:42 PM, Alejandra Infante wrote: >> Hi, >> I understand that ICV is an estimated measure based on a standard >> talairach transformation; however, I want to know how freesurfer >> is defining intracranial volume (i.e., is this a representation >> of everything within the cranium as the name implies or is it an >> estimate of total brain volume, which would not include space >> between skull and dura)?. We are using fs vesion 5.1 >> >> >> -- >> M. Alejandra Infante >> Doctoral Student >> SDSU/UCSD Joint Doctoral Program in Clinical Psychology >> Phone: (858) 449-2950 <tel:%28858%29%20449-2950> >> E-Mail: infante.alejandr...@gmail.com >> <mailto:infante.alejandr...@gmail.com> >> >> >> >> _______________________________________________ >> Freesurfer mailing list >> Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu> >> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > The information in this e-mail is intended only for the person to > whom it is > addressed. If you believe this e-mail was sent to you in error and > the e-mail > contains patient information, please contact the Partners > Compliance HelpLine at > http://www.partners.org/complianceline . If the e-mail was sent to > you in error > but does not contain patient information, please contact the > sender and properly > dispose of the e-mail. > > > > > -- > M. Alejandra Infante > Doctoral Student > SDSU/UCSD Joint Doctoral Program in Clinical Psychology > Phone: (858) 449-2950 > E-Mail: infante.alejandr...@gmail.com > <mailto:infante.alejandr...@gmail.com> > -- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
