Hi, A follow up question pertaining to this issue for me is how good is the measure of the ICV when dealing with subjects having prior resections or significant atrophy. I am using FreeSurfer v5.1.
Thank you M. Goryawala Post-Doctoral Associate Florida International University Miami, FL On Wed, May 8, 2013 at 11:53 AM, Alejandra Infante < infante.alejandr...@gmail.com> wrote: > Thank you! > > Sent from my iPhone > > On May 8, 2013, at 8:17 AM, Douglas N Greve <gr...@nmr.mgh.harvard.edu> > wrote: > > > > > Hi Alejandra, I don't work with children, so I'll let someone else > (Lilla? Rudolph?) answer. > > doug > > ps. Please remember to copy the list on responses. Thanks! > > > > On 05/08/2013 01:19 AM, Alejandra Infante wrote: > >> Thank you! I might have asked this at the training, but I am still not > clear on whether the estimated ICV (from freesurfer) is reliable if your > population of interest are children? Or would you recommend manual edits > (when needed) after checking the quality of the talairach registration file > using tkregister2 --s subjid --fstal --surfs? > >> > >> > >> On Tue, May 7, 2013 at 7:52 PM, Douglas Greve < > gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote: > >> > >> > >> It is neither:) See http://surfer.nmr.mgh.harvard.edu/fswiki/eTIV > >> and/or Buckner et al. (2004) NeuroImage > >> <https://surfer.nmr.mgh.harvard.edu/fswiki/NeuroImage> 23:724-738. > >> > >> "Basically, total intracranial volume is found to correlate with > >> the determinant of the transform matrix used to align an image > >> with an atlas. The work demonstrates that a one-parameter scaling > >> factor provides a reasonable TIV estimation. This method uses an > >> atlas based spatial normalization procedure, and requires that the > >> *talairach.xfm* is correct. " > >> > >> This performs the talairach registration for a subject. Then, > >> based only on the numbers in the matrix, it estimates the ICV > >> based on subjects that had similar matrices. > >> > >> doug > >> > >> > >> > >> On 5/7/13 9:42 PM, Alejandra Infante wrote: > >>> Hi, > >>> I understand that ICV is an estimated measure based on a standard > >>> talairach transformation; however, I want to know how freesurfer > >>> is defining intracranial volume (i.e., is this a representation > >>> of everything within the cranium as the name implies or is it an > >>> estimate of total brain volume, which would not include space > >>> between skull and dura)?. We are using fs vesion 5.1 > >>> > >>> > >>> -- M. Alejandra Infante > >>> Doctoral Student > >>> SDSU/UCSD Joint Doctoral Program in Clinical Psychology > >>> Phone: (858) 449-2950 <tel:%28858%29%20449-2950> > >>> E-Mail: infante.alejandr...@gmail.com > >>> <mailto:infante.alejandr...@gmail.com> > >>> > >>> > >>> > >>> _______________________________________________ > >>> Freesurfer mailing list > >>> Freesurfer@nmr.mgh.harvard.edu <mailto: > Freesurfer@nmr.mgh.harvard.edu> > >>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > >> > >> > >> _______________________________________________ > >> Freesurfer mailing list > >> Freesurfer@nmr.mgh.harvard.edu <mailto: > Freesurfer@nmr.mgh.harvard.edu> > >> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > >> > >> > >> The information in this e-mail is intended only for the person to > >> whom it is > >> addressed. If you believe this e-mail was sent to you in error and > >> the e-mail > >> contains patient information, please contact the Partners > >> Compliance HelpLine at > >> http://www.partners.org/complianceline . If the e-mail was sent to > >> you in error > >> but does not contain patient information, please contact the > >> sender and properly > >> dispose of the e-mail. > >> > >> > >> > >> > >> -- > >> M. Alejandra Infante > >> Doctoral Student > >> SDSU/UCSD Joint Doctoral Program in Clinical Psychology > >> Phone: (858) 449-2950 > >> E-Mail: infante.alejandr...@gmail.com <mailto: > infante.alejandr...@gmail.com> > > > > -- > > Douglas N. Greve, Ph.D. > > MGH-NMR Center > > gr...@nmr.mgh.harvard.edu > > Phone Number: 617-724-2358 > > Fax: 617-726-7422 > > > > Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting > > FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 > > www.nmr.mgh.harvard.edu/facility/filedrop/index.html > > Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ > > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer >
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