Thank you! Sent from my iPhone
On May 8, 2013, at 8:17 AM, Douglas N Greve <gr...@nmr.mgh.harvard.edu> wrote: > > Hi Alejandra, I don't work with children, so I'll let someone else (Lilla? > Rudolph?) answer. > doug > ps. Please remember to copy the list on responses. Thanks! > > On 05/08/2013 01:19 AM, Alejandra Infante wrote: >> Thank you! I might have asked this at the training, but I am still not clear >> on whether the estimated ICV (from freesurfer) is reliable if your >> population of interest are children? Or would you recommend manual edits >> (when needed) after checking the quality of the talairach registration file >> using tkregister2 --s subjid --fstal --surfs? >> >> >> On Tue, May 7, 2013 at 7:52 PM, Douglas Greve <gr...@nmr.mgh.harvard.edu >> <mailto:gr...@nmr.mgh.harvard.edu>> wrote: >> >> >> It is neither:) See http://surfer.nmr.mgh.harvard.edu/fswiki/eTIV >> and/or Buckner et al. (2004) NeuroImage >> <https://surfer.nmr.mgh.harvard.edu/fswiki/NeuroImage> 23:724-738. >> >> "Basically, total intracranial volume is found to correlate with >> the determinant of the transform matrix used to align an image >> with an atlas. The work demonstrates that a one-parameter scaling >> factor provides a reasonable TIV estimation. This method uses an >> atlas based spatial normalization procedure, and requires that the >> *talairach.xfm* is correct. " >> >> This performs the talairach registration for a subject. Then, >> based only on the numbers in the matrix, it estimates the ICV >> based on subjects that had similar matrices. >> >> doug >> >> >> >> On 5/7/13 9:42 PM, Alejandra Infante wrote: >>> Hi, >>> I understand that ICV is an estimated measure based on a standard >>> talairach transformation; however, I want to know how freesurfer >>> is defining intracranial volume (i.e., is this a representation >>> of everything within the cranium as the name implies or is it an >>> estimate of total brain volume, which would not include space >>> between skull and dura)?. We are using fs vesion 5.1 >>> >>> >>> -- M. Alejandra Infante >>> Doctoral Student >>> SDSU/UCSD Joint Doctoral Program in Clinical Psychology >>> Phone: (858) 449-2950 <tel:%28858%29%20449-2950> >>> E-Mail: infante.alejandr...@gmail.com >>> <mailto:infante.alejandr...@gmail.com> >>> >>> >>> >>> _______________________________________________ >>> Freesurfer mailing list >>> Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu> >>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer >> >> >> _______________________________________________ >> Freesurfer mailing list >> Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu> >> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer >> >> >> The information in this e-mail is intended only for the person to >> whom it is >> addressed. If you believe this e-mail was sent to you in error and >> the e-mail >> contains patient information, please contact the Partners >> Compliance HelpLine at >> http://www.partners.org/complianceline . If the e-mail was sent to >> you in error >> but does not contain patient information, please contact the >> sender and properly >> dispose of the e-mail. >> >> >> >> >> -- >> M. Alejandra Infante >> Doctoral Student >> SDSU/UCSD Joint Doctoral Program in Clinical Psychology >> Phone: (858) 449-2950 >> E-Mail: infante.alejandr...@gmail.com <mailto:infante.alejandr...@gmail.com> > > -- > Douglas N. Greve, Ph.D. > MGH-NMR Center > gr...@nmr.mgh.harvard.edu > Phone Number: 617-724-2358 > Fax: 617-726-7422 > > Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting > FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 > www.nmr.mgh.harvard.edu/facility/filedrop/index.html > Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ > _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer