Hi Harry,

The first thing that comes to mind is any sort of light harvesting complex - 
take a look at 1RWT. Would that fit the bill?

D




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Dr David C. Briggs CSci MRSB (he/him)

Principal Laboratory Research Scientist

Signalling and Structural Biology Lab

The Francis Crick Institute

London, UK

Working hours: Mon-Fri 0900-1700

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"Would it not be better if one could really 'see' whether molecules...were just 
as experiments suggested?"

– Dorothy Hodgkin

________________________________
From: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK> on behalf of Harry Powell 
<0000193323b1e616-dmarc-requ...@jiscmail.ac.uk>
Sent: 20 December 2024 10:37
To: CCP4BB@JISCMAIL.AC.UK <CCP4BB@JISCMAIL.AC.UK>
Subject: [ccp4bb] enzyme or other protein with multiple cofactors


External Sender: Use caution.


Hi folks

I’m familiar with enzymes that have a single co-factor (for example haem in 
myoglobin [or in the individual chains in haemoglobins] or FAD in 
flavoproteins), but was wondering if there are examples of single-chain 
proteins that have multiple cofactors (or even multiple chain proteins that 
have multiple cofactors bound to a single chain)?

I’m not bothered (at the moment) about proteins that have cofactors bound to 
different chains.

I thought this would be a good place to ask…

Harry
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