Perhaps you should tell us a bit more on refinement. What program, how many reflections to refine against, how many atoms to refine, is there any NCS that can be used as a constraint or restraint etc. This would allow us to give you advice.

Fred.

Vandana Kukshal wrote:
hi
i am solving one structure

in which after refinement i got R factor=27
and R free =27.7
i want to know that is it correct or i did some over refinment

the Resolution is 3.0 A

<<attachment: Frederic_Vellieux.vcf>>

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