External Email - Use Caution Many thanks, Doug! Should I then rely on groups' means to determine the 'direction of the result', and not on the 'max statistical significance' signal? Does 'abs' simulation sum up the results I could get by running 'pos' and 'neg' simulations separately? Best
On Mon, May 14, 2018 at 7:13 PM, Douglas N. Greve <dgr...@mgh.harvard.edu> wrote: > You have specified "abs" meaning an unsigned "absolute" test, so there > is no guarantee that the mean contrast will be pos or neg. > > > On 05/14/2018 06:11 PM, Pedro Rosa wrote: > > > > > > Here it is: mri_glmfit-sim --glmdir > > PEP-HC_Gender_Age.txt.lh.area.mgh.5.mgh.cortex.glmdir --sim-sign abs > > --cache 1.3 abs > > > > On Mon, May 14, 2018 at 6:59 PM, Douglas N. Greve > > <dgr...@mgh.harvard.edu <mailto:dgr...@mgh.harvard.edu>> wrote: > > > > sorry, one more thing. Can you send your mri_glmfit-sim command line? > > > > > > On 05/14/2018 05:46 PM, Pedro Rosa wrote: > > > > > > > > > Hi, Doug. Many thanks. > > > Find the fsgd and the contrast attached, as well as the cluster > > > summary and the individual-based cluster data (which I used to > > > calculate the groups' means). The cluster I referred to is the > > second > > > one (medialorbitofrontal). > > > I investigated differences in cortical area from groups 1 and 2 in > > > contrast to groups 3 and 4 (contrast 3 as in > > > https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf4G1V > > <https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf4G1V>). > > > Best, > > > Pedro Rosa. > > > > > > On Mon, May 14, 2018 at 5:42 PM, Douglas N. Greve > > > <dgr...@mgh.harvard.edu <mailto:dgr...@mgh.harvard.edu> > > <mailto:dgr...@mgh.harvard.edu <mailto:dgr...@mgh.harvard.edu>>> > > wrote: > > > > > > Can you send your fsgd file and contrasts? > > > > > > > > > On 05/14/2018 01:25 PM, Pedro Rosa wrote: > > > > > > > > > > > > Dear FreeSurfers, > > > > I got results from a cortical area analysis that intrigued > > me: Upon > > > > the inspection of clusters that survived Monte-Carlo > > simulation, I > > > > found a cluster with larger area among a first group in > > contrast > > > to a > > > > second group. > > > > However, when I calculated the cortical areas means from that > > > cluster > > > > (as available in the glmdir), the second group had values > > slightly > > > > larger than the first group (i.e., showing a difference in > the > > > > opposite direction). > > > > How would you explain such findings? Must I have committed a > > > mistake > > > > in the analysis or its interpretation? > > > > Best, > > > > Pedro Rosa - University of São Paulo - Brazil. > > > > > > > > > > > > _______________________________________________ > > > > Freesurfer mailing list > > > > Freesurfer@nmr.mgh.harvard.edu > > <mailto:Freesurfer@nmr.mgh.harvard.edu> > > > <mailto:Freesurfer@nmr.mgh.harvard.edu > > <mailto:Freesurfer@nmr.mgh.harvard.edu>> > > > > > > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer> > > > <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer>> > > > > > > _______________________________________________ > > > Freesurfer mailing list > > > Freesurfer@nmr.mgh.harvard.edu > > <mailto:Freesurfer@nmr.mgh.harvard.edu> > > <mailto:Freesurfer@nmr.mgh.harvard.edu > > <mailto:Freesurfer@nmr.mgh.harvard.edu>> > > > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer> > > > > > <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer>> > > > > > > > > > The information in this e-mail is intended only for the > > person to > > > whom it is > > > addressed. 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