Dear Freesurfer-Experts,

I am currently trying to measure Cortical Thickness of a
Volume-defined ROI in a patient measured at 4 timepoints.

Basically, I am interested in a ROI resulting from fMRI activation
measured on Timepoint 1.
I would then like to get thickness values in the same ROI for all
Timepoints 1-4.

I have read the instructions here:
https://surfer.nmr.mgh.harvard.edu/fswiki/VolumeRoiCorticalThickness
this works.

now, my idea is:

ROI from TP1 >> register to base image of longit. recon. ("base")
ROI from base >> TP1.long (from long recon)
ROI from base >> TP2.long (from long recon)
ROI from base >> TP3 long (from long recon)
ROI from base >> TP4.long (from long recon)

OR should I simpy map my ROI to fsaverage and project it back all
individual timepoints?
ROI from TP1 >> register to fsaverage
ROI from fsaverage >> TP1 (not from long recon)
ROI from fsaverage >> TP2 (not from long recon)
etc.

I understand that registration using the long. recon is more robust...

Best regards,
Bastian
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