Hi Bastian,

use the longitudinal base for it. Also, once your ROI is in that space 
you can simply apply it in each long as they are in the same space as 
the base. The registration of base >> TP1.long etc. probably only 
changes results very little.

Best, Martin


On 07/18/2014 10:45 AM, Bastian Cheng wrote:
> Dear Freesurfer-Experts,
>
> I am currently trying to measure Cortical Thickness of a
> Volume-defined ROI in a patient measured at 4 timepoints.
>
> Basically, I am interested in a ROI resulting from fMRI activation
> measured on Timepoint 1.
> I would then like to get thickness values in the same ROI for all
> Timepoints 1-4.
>
> I have read the instructions here:
> https://surfer.nmr.mgh.harvard.edu/fswiki/VolumeRoiCorticalThickness
> this works.
>
> now, my idea is:
>
> ROI from TP1 >> register to base image of longit. recon. ("base")
> ROI from base >> TP1.long (from long recon)
> ROI from base >> TP2.long (from long recon)
> ROI from base >> TP3 long (from long recon)
> ROI from base >> TP4.long (from long recon)
>
> OR should I simpy map my ROI to fsaverage and project it back all
> individual timepoints?
> ROI from TP1 >> register to fsaverage
> ROI from fsaverage >> TP1 (not from long recon)
> ROI from fsaverage >> TP2 (not from long recon)
> etc.
>
> I understand that registration using the long. recon is more robust...
>
> Best regards,
> Bastian
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>
>

-- 
Martin Reuter, Ph.D.

Instructor in Neurology
   Harvard Medical School
Assistant in Neuroscience
   Dept. of Radiology, Massachusetts General Hospital
   Dept. of Neurology, Massachusetts General Hospital
Research Affiliate
   Computer Science and Artificial Intelligence Lab,
   Dept. of Electrical Engineering and Computer Science,
   Massachusetts Institute of Technology

A.A.Martinos Center for Biomedical Imaging
149 Thirteenth Street, Suite 2301
Charlestown, MA 02129

Phone: +1-617-724-5652
Email:
    mreu...@nmr.mgh.harvard.edu
    reu...@mit.edu
Web  : http://reuter.mit.edu

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