Thank you for clarification, Martin!

Will do so and also try registration of  base >> TP1.long etc.

Does FS create registration files (.dat) for this purpose
automatically? I found some *.lta files in the /mri/transfers folder
of the base image but am not sure how to apply them (maybe
tkregister2?)

best regards,
Bastian

On 18 July 2014 23:00, Martin Reuter <mreu...@nmr.mgh.harvard.edu> wrote:
> Hi Bastian,
>
> use the longitudinal base for it. Also, once your ROI is in that space
> you can simply apply it in each long as they are in the same space as
> the base. The registration of base >> TP1.long etc. probably only
> changes results very little.
>
> Best, Martin
>
>
> On 07/18/2014 10:45 AM, Bastian Cheng wrote:
>> Dear Freesurfer-Experts,
>>
>> I am currently trying to measure Cortical Thickness of a
>> Volume-defined ROI in a patient measured at 4 timepoints.
>>
>> Basically, I am interested in a ROI resulting from fMRI activation
>> measured on Timepoint 1.
>> I would then like to get thickness values in the same ROI for all
>> Timepoints 1-4.
>>
>> I have read the instructions here:
>> https://surfer.nmr.mgh.harvard.edu/fswiki/VolumeRoiCorticalThickness
>> this works.
>>
>> now, my idea is:
>>
>> ROI from TP1 >> register to base image of longit. recon. ("base")
>> ROI from base >> TP1.long (from long recon)
>> ROI from base >> TP2.long (from long recon)
>> ROI from base >> TP3 long (from long recon)
>> ROI from base >> TP4.long (from long recon)
>>
>> OR should I simpy map my ROI to fsaverage and project it back all
>> individual timepoints?
>> ROI from TP1 >> register to fsaverage
>> ROI from fsaverage >> TP1 (not from long recon)
>> ROI from fsaverage >> TP2 (not from long recon)
>> etc.
>>
>> I understand that registration using the long. recon is more robust...
>>
>> Best regards,
>> Bastian
>> _______________________________________________
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>>
>>
>
> --
> Martin Reuter, Ph.D.
>
> Instructor in Neurology
>    Harvard Medical School
> Assistant in Neuroscience
>    Dept. of Radiology, Massachusetts General Hospital
>    Dept. of Neurology, Massachusetts General Hospital
> Research Affiliate
>    Computer Science and Artificial Intelligence Lab,
>    Dept. of Electrical Engineering and Computer Science,
>    Massachusetts Institute of Technology
>
> A.A.Martinos Center for Biomedical Imaging
> 149 Thirteenth Street, Suite 2301
> Charlestown, MA 02129
>
> Phone: +1-617-724-5652
> Email:
>     mreu...@nmr.mgh.harvard.edu
>     reu...@mit.edu
> Web  : http://reuter.mit.edu
>
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