Hi Colin,

Marin's mail included a URL that had other links, at what stage I
stopped following. I was rather amused by an email about microscopy
being sent to a crystallography board - or rather not amused, because
the confusion of both has led to a serious deterioration of quality of
publications in ED.

I do not have a problem with a phenomenon only because I don't
understand it. The statistical part in QM is a matter of fact, so why
call it a measurement "problem"? A crystal is a beautiful quantum
calculator that modifies the probability distribution of a planar wave
into a series of spots - that's so beautiful, and I don't worry if the
photons or other diffracted particles do not arrive at the detector in
the order I want them to arrive, as long as they do arrive ;-)

Cheers,
Tim


On Mon, 6 Oct 2025 15:24:06 +0000 "Nave, Colin (DLSLtd,RAL,LSCI)"
<[email protected]> wrote:

> Sorry Tim,
> I very much doubt that Marin's analysis does not apply equally to
> x-ray diffraction. Apart from imaging being just equivalent to 1 unit
> cell, crystallography increasingly uses photon counting detectors
> which, according to Marin,  will also have a direct connection to the
> measurement problem. Investigating this could be like falling down a
> rabbit hole. You might now have to spend sleepless nights worry about
> the fundamental basis of what you have been doing since you started
> your career.
> 
> If you want to avoid this, one can just accept that the measurement
> problem is similar to trying to determine which slit a particle goes
> through in a 2 slit experiment. This could involve choosing one of
> the many interpretations of quantum mechanics. Or you could otherwise
> accept it is a central mystery and leave it at that.
> 
> Of course, Marin might have solved this central mystery!
> 
> Good luck
>    Colin
> 
> -----Original Message-----
> From: CCP4 bulletin board <[email protected]> On Behalf Of Tim
> Gruene Sent: 06 October 2025 14:46
> To: [email protected]
> Subject: Re: [ccp4bb] Single Electron Counting, The Measurement
> Problem, Symmetric Sampling
> 
> I am so happy I do diffraction, not microscopy Tim
> 
> On Sat, 4 Oct 2025 19:13:10 -0300
> Marin van Heel <[email protected]> wrote:
> 
>  [...]  
> 
> 
> 
> --
> --
> Tim Gruene
> Head of the Core Facility Crystal Structure Analysis Faculty of
> Chemistry University of Vienna
> 
> Phone: +43-1-4277-70202
> 
> https://ccsa.univie.ac.at
> 
> GPG Key ID = A46BEE1A
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-- 
Tim Gruene
Head of the CF Crystal Structure Analysis
Faculty of Chemistry
University of Vienna

Phone: +43-1-4277-70202

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