Tim, the so-called "measurement" problem in QM is a real problem because
no-one has yet provided a testable theory of the mechanism of wavefunction
"collapse" and there as many theories for it as there are interpretations
of QM.  For example, Roger Penrose suggests that it's caused by interaction
of the quantum system with a gravitational field (
https://en.wikipedia.org/wiki/Penrose_interpretation).

-- Ian

On Mon, 6 Oct 2025 at 21:21, Tim Gruene <
[email protected]> wrote:

> Hi Colin,
>
> Marin's mail included a URL that had other links, at what stage I
> stopped following. I was rather amused by an email about microscopy
> being sent to a crystallography board - or rather not amused, because
> the confusion of both has led to a serious deterioration of quality of
> publications in ED.
>
> I do not have a problem with a phenomenon only because I don't
> understand it. The statistical part in QM is a matter of fact, so why
> call it a measurement "problem"? A crystal is a beautiful quantum
> calculator that modifies the probability distribution of a planar wave
> into a series of spots - that's so beautiful, and I don't worry if the
> photons or other diffracted particles do not arrive at the detector in
> the order I want them to arrive, as long as they do arrive ;-)
>
> Cheers,
> Tim
>
>
> On Mon, 6 Oct 2025 15:24:06 +0000 "Nave, Colin (DLSLtd,RAL,LSCI)"
> <[email protected]> wrote:
>
> > Sorry Tim,
> > I very much doubt that Marin's analysis does not apply equally to
> > x-ray diffraction. Apart from imaging being just equivalent to 1 unit
> > cell, crystallography increasingly uses photon counting detectors
> > which, according to Marin,  will also have a direct connection to the
> > measurement problem. Investigating this could be like falling down a
> > rabbit hole. You might now have to spend sleepless nights worry about
> > the fundamental basis of what you have been doing since you started
> > your career.
> >
> > If you want to avoid this, one can just accept that the measurement
> > problem is similar to trying to determine which slit a particle goes
> > through in a 2 slit experiment. This could involve choosing one of
> > the many interpretations of quantum mechanics. Or you could otherwise
> > accept it is a central mystery and leave it at that.
> >
> > Of course, Marin might have solved this central mystery!
> >
> > Good luck
> >    Colin
> >
> > -----Original Message-----
> > From: CCP4 bulletin board <[email protected]> On Behalf Of Tim
> > Gruene Sent: 06 October 2025 14:46
> > To: [email protected]
> > Subject: Re: [ccp4bb] Single Electron Counting, The Measurement
> > Problem, Symmetric Sampling
> >
> > I am so happy I do diffraction, not microscopy Tim
> >
> > On Sat, 4 Oct 2025 19:13:10 -0300
> > Marin van Heel <[email protected]> wrote:
> >
> >  [...]
> >
> >
> >
> > --
> > --
> > Tim Gruene
> > Head of the Core Facility Crystal Structure Analysis Faculty of
> > Chemistry University of Vienna
> >
> > Phone: +43-1-4277-70202
> >
> > https://ccsa.univie.ac.at
> >
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> --
> Tim Gruene
> Head of the CF Crystal Structure Analysis
> Faculty of Chemistry
> University of Vienna
>
> Phone: +43-1-4277-70202
>
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