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Dear Freesurfer Expert,

We would like to extract mean Cth values for each subject within a own-creaded 
ROI (surface defined), using freeview (for instance). Is it possible to create 
a ROI (i.e. spherical surface) surrounding a particular vertex of an sig.mgh 
file? (and then extract its mean Cth values for each subject)?

I think this is not a new question, and it was posted somehow on 
https://secure-web.cisco.com/15jmZMEaxCepVMfyQImwGR_dFusKbz7ObR8zcE3AMwMwg6FQ-QTkuETE4n5SJPU_y-ULxR0ToQgr0B_LnZ-TU71vd9-uYDXh55K9eVQ23CX9kaJT60pYOX0pH6tJ69K_Ry--XuPl1mkS0Vm-sSsWKWe2iqWjc5l2Y91tqImFy3Fb1NHtO7eCCpFk8I3Th1ljqxlnFLLOdjxe5bNpse_tYAPw-_J4V3X1Y9ONydytuj8eYC1Ly6c51azXalSlz6ZF_Xa9SbBJbXCJ6wvPAnlRqcmLPaBSCkzxpYzHM8250uaUvkwrVXDetf4ppJsTfDiNl/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FFsTutorial%2FQuestionAnswers,
 and 
https://secure-web.cisco.com/1nS4AASSkp9fTCLDzqspNVvBf35PGarlPS708pOXtzpIMD4eASchvVbZLp65PS17HOn4cF-QEOKrz967tFrvqCTjlc-sB9fVuMI1CEUkb5m657oRe3DpyjwX9zSi3drP0cPEFBtrQe-2wfm3lQVO166f3QJao-Pq2XbpVRgo5UBgmt7oKBFbiBCBvj_534G45CEE2U9KkR7EjTPPn1W6w0ur3GGywIbW1Fh8AqeJa-QPpV2hrOWwEiX9Xkh3Dh4lveR2CDXf04WAXrlgdNdDnyqPZDbW1k45Pa1C37Ew1sU8dfqpWbKwdc1z2jO2R6EHx/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg67677.html,
 but I'm still encountering questions.

These commands did run, but together they didn't create a binarized mask with 1 
for the sphere around the coordinates, and 0 for the other voxels. Would you 
recommend what I should change? Thank you so much!

$mri_volsynth --template $SUBJECTS_DIR/fsaverage/surf/lh.thickness --pdf sphere 
--sphere-center -7.4 67.22 60.27 --radius 5 --o delta.sm00.mgh
$mris_fwhm \
--smooth-only \
--subject fsaverage \
--hemi lh \
--i delta.sm00.mgh \
--niters 10 \
--o delta.sm10.mgh
$mri_binarize --i delta.sm10.mgh --min 10e-5 --o delta.sm10.bin.mgh


Regards,
Xiaoxu

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