Yes, it will work on both. If you use a table, then pass the table with --table tablefile instead of --y

On 7/12/2021 7:54 AM, Ritobrato Datta wrote:

        External Email - Use Caution

Good morning,

Thanks Doug for the answers. Quick naive question. The analyses I want to perform are on volumetric data parcellated using aseg and not surface data.

Does mri_glmfit work with the output of the asegstats2table or on voxelwise FA maps ?

Many thanks

Rito

On Fri, Jul 9, 2021 at 4:04 PM Douglas N. Greve <dgr...@mgh.harvard.edu <mailto:dgr...@mgh.harvard.edu>> wrote:



    On 7/9/2021 11:44 AM, Ritobrato Datta wrote:

            External Email - Use Caution

    Hi All,


    I have the following data –

    I have 205 subjects - each subject was imaged at 3 timepoints
    (baseline, followup 1 and followup 2)

    The 205 subjects are split in two treatment arms with 100
    subjects in the first one and 105 subjects in the second one.

    For each timepoint, I have created FA maps in their native
    diffusion space.

    I have also extracted the mean FA maps for 187 ROIs using
    mri_segstats.

    For each timepoint, I have saved the results as a matrix (FA in
    187 ROIs x 205 subjects) in a text file.

    So I have three files for the three timepoints.

    I have the age and cognitive score for each subject at each
    timepoint. And their gender.

    I want to answer the following questions –

     1. Do the baseline FA correlate with the corresponding cognitive
        score at baseline ?

    This is a straight forward group analysis, so see *MailScanner has
    detected a possible fraud attempt from "secure-web.cisco.com"
    claiming to be*
    https://surfer.nmr.mgh.harvard.edu/fswiki/FsgdExamples
    
<https://secure-web.cisco.com/1kTEkM43RMM06eViww_c18Pc-0P94xql3L2qK8iLarzzC3y3ZVsJIyVlzwF_FfFDswP_67I4PBLfYANWVTXuX-4X-dgKz6-k68o_AL_cvOJiFFFtpwIkd_pFO6m_tuaJtslVIIdmaO4umpQP9t8aMp-MPFEXKVDhKSsBgBNLINu7lLfDwLYKxiP2ZBbWcSlnNZ_KCTA3HDdKNI3PG_H6HTqTiwoC5vQjUicP6uxqYdn-HGl01ZnCt5V89LbOE3usywXIQtA_sZ4MgIcXGQDbj2g/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FFsgdExamples>
 (maybe
    the Two Groups (1 Factor, Two Levels), One Covariate
    
<https://secure-web.cisco.com/1Rg-kxMT-3fQYeRaisunO8_YESB0oLHn151lBD4p9GXp_k96wsb_0fS3wm9AsXst9uQO9dbqRePqf6ijMZUnk_-eFE6HtBGPMjtgURPbRAk_5EC3Q0F3VX-mhUssaYthkDfBZtL6yv0bGjJhKRQulYDXsfvmbpUWl4VH11l7cdQD2p1m_QzCr5liecQPY6UPX6OiGxGITQdALxOE9JdoIyXv0aJ_ozwU_Lw9H2pA2lcXdQEb4RTfOartXbc2P58SNR1mmH4DIzvfp7MxOG1oqRA/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FFsgdf2G1V>)


     1. I am interested in testing whether the FA changed
        significantly across the different timepoints and does that
        relate to the change in the cognitive score

    See *MailScanner has detected a possible fraud attempt from
    "secure-web.cisco.com" claiming to be*
    https://surfer.nmr.mgh.harvard.edu/fswiki/RepeatedMeasuresAnova
    
<https://secure-web.cisco.com/1l3pHvz1wZceoR8e52Wja_MsMNej9vi7VZZmS8c-z4MS9JGbI3TYJJMikCYf0s7kjh03rhGqRoz4Nqw5FjnWspM8jPaxx5vhTf6cgH1nVEw8kZAyGg-kIVm5tQNWqRiQ-S-cYslSRjWA5zKzXqqcgwKeSWShLW2aw-XRuSrV9IBOmdGQq2pERdmOAqXTVIKchIwtjPqefKoRqoYe4OZ6h_wlLLnBEFs_BJGv4A9Eabyq07igMiO8NeE8VYMkEhQFl0KlX_VyWmlAm-N28VS8hcg/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FRepeatedMeasuresAnova>

     1. Is there an effect of treatment on this change in FA across
        time ?

    Also see *MailScanner has detected a possible fraud attempt from
    "secure-web.cisco.com" claiming to be*
    https://surfer.nmr.mgh.harvard.edu/fswiki/RepeatedMeasuresAnova
    
<https://secure-web.cisco.com/1l3pHvz1wZceoR8e52Wja_MsMNej9vi7VZZmS8c-z4MS9JGbI3TYJJMikCYf0s7kjh03rhGqRoz4Nqw5FjnWspM8jPaxx5vhTf6cgH1nVEw8kZAyGg-kIVm5tQNWqRiQ-S-cYslSRjWA5zKzXqqcgwKeSWShLW2aw-XRuSrV9IBOmdGQq2pERdmOAqXTVIKchIwtjPqefKoRqoYe4OZ6h_wlLLnBEFs_BJGv4A9Eabyq07igMiO8NeE8VYMkEhQFl0KlX_VyWmlAm-N28VS8hcg/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FRepeatedMeasuresAnova>

    Can you please suggest what programs in freesurfer will allow me
    to test these questions on both voxelwise and ROI wise ?


    Many thanks for your help and guidance,


    Regards


    Rito


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On Fri, Jul 9, 2021 at 11:44 AM Ritobrato Datta <ribrains...@gmail.com <mailto:ribrains...@gmail.com>> wrote:

    Hi All,


    I have the following data –

    I have 205 subjects - each subject was imaged at 3 timepoints
    (baseline, followup 1 and followup 2)

    The 205 subjects are split in two treatment arms with 100 subjects
    in the first one and 105 subjects in the second one.

    For each timepoint, I have created FA maps in their native
    diffusion space.

    I have also extracted the mean FA maps for 187 ROIs using
    mri_segstats.

    For each timepoint, I have saved the results as a matrix (FA in
    187 ROIs x 205 subjects) in a text file.

    So I have three files for the three timepoints.

    I have the age and cognitive score for each subject at each
    timepoint. And their gender.

    I want to answer the following questions –

     1. Do the baseline FA correlate with the corresponding cognitive
        score at baseline ?
     2. I am interested in testing whether the FA changed
        significantly across the different timepoints and does that
        relate to the change in the cognitive score
     3. Is there an effect of treatment on this change in FA across time ?

    Can you please suggest what programs in freesurfer will allow me
    to test these questions on both voxelwise and ROI wise ?


    Many thanks for your help and guidance,


    Regards


    Rito


_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

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