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Hi Bruce,

Thanks, but in this case will recon-all with -bigventricles flag work well
on normal patients without big ventricles ?

Best,
Matthieu

2018-09-18 15:56 GMT+00:00 Bruce Fischl <fis...@nmr.mgh.harvard.edu>:

> Hi Matthieu
>
> yes, you will want to run all of your subjects with it
>
> cheers
> Bruce
> On Tue, 18 Sep 2018, Matthieu Vanhoutte wrote:
>
>
>>         External Email - Use Caution
>>
>> Dear Bram,
>>
>> It looks like the -bigventricles flag fixed my problem with my specific
>> subject. Not only, this took
>> into account large ventricles but also corrected grey matter segmentation
>> from extra Dura tissue
>> that was erroneously segmented in GM.
>>
>> I understand the first point of amelioration allowed by the flag but
>> don't understand where the
>> second point come from ?
>>
>> If I used the -bigventricles flag for all my atrophied and large
>> ventricles patients and not for my
>> healthy patients, wouldn't it introduce a bias when further statistically
>> comparing groups between
>> them ?
>>
>> Best,
>> Matthieu
>>
>> 2018-09-14 15:35 GMT+00:00 Diamond, Bram Ryder <brdiam...@mgh.harvard.edu
>> >:
>>       If you haven't already, you may want to run the subject through
>> recon-all with the
>>       -bigventricles flag since it looks like the lateral ventricle was
>> significantly
>>       mislabeled in the aseg. If using the -bigventricles flag doesn't
>> fix your problem, you
>>       can edit the aseg.mgz manually by following the directions in this
>> tutorial. Then run
>>       the following command (again, substituting <subj_id> for your
>> subject's id):
>> recon-all -autorecon2-noaseg -autorecon3 -subjid <subj_id>
>>
>> I would try this before doing the wm.mgz edits I suggested in my previous
>> email.
>>
>> Best,
>> Bram
>>
>> ____________________________________________________________
>> ________________________________________
>>
>> From: freesurfer-boun...@nmr.mgh.harvard.edu <
>> freesurfer-boun...@nmr.mgh.harvard.edu> on
>> behalf of Diamond, Bram Ryder <brdiam...@mgh.harvard.edu>
>> Sent: Friday, September 14, 2018 11:07:42 AM
>> To: matthieuvanhou...@gmail.com
>> Cc: freesurfer@nmr.mgh.harvard.edu; astev...@nmr.mgh.harvard.edu
>> Subject: [Freesurfer] Troubles to determine the type of recon editing
>> needed
>>
>> Hi Matthieu,
>>
>>
>> I've taken a look through the files you shared with us and I see the poor
>> surfaces in the
>> posterior right hemisphere you were referring to in your message. It
>> looks like your subject
>> has a combination of abnormally large ventricles and significant wm
>> abnormalities, so I'm
>> surprised FreeSurfer did as well as it did.
>>
>>
>> As for the recon editing - I would recommend editing the wm.mgz to more
>> accurately represent
>> the wm from slice 84 to 39. You can take a look at the white matter edits
>> tutorial for details
>> on how to do that. Then run the following command (substituting <subj_id>
>> for your
>> subject's id):
>>
>>
>> recon-all -autorecon2-wm -autorecon3 -subjid <subj_id>
>>
>>
>> The surface reconstruction may also benefit from labeling the right
>> lateral ventricle in the
>> wm.mgz (as an intensity of 250) - but I'm not certain since you didn't
>> send us the surfaces
>> for the left hemisphere. Before you do that, edit the wm.mgz as explained
>> in the tutorial and
>> tell us how that goes.
>>
>>
>> All the best,
>>
>> Bram
>>
>>
>> Bram R. Diamond, BSc
>> Research Technician II
>> Laboratory for Computational Neuroimaging
>> Martinos Center for Biomedical Imaging
>> Massachusetts General Hospital
>> 149 13th Street
>> Charlestown, MA 02129
>> (p): 617-726-6598
>>
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>>
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