mri_glmfit will not generate a pcc file with --pvr. I think I just did 
not get around to adding support for this. What about the sig does not 
look right? You can often get funny looking maps because each voxel is a 
different design matrix.


On 05/09/2017 03:15 PM, Martin Juneja wrote:
> Dear Dr. Greve,
>
> I created two stacks: one with volume and the other with LGI using 
> mris commands as following:
>
> mris_preproc --fsgd CV_LGI.fsgd --target fsaverage --hemi lh --meas 
> volume --out Corr_CV_LGI/lh.vol.mgh
> mris_preproc --fsgd CV_LGI.fsgd --target fsaverage --hemi lh --meas 
> pial_lgi --out Corr_CV_LGI/lh.LGI.mgh
>
> Then I smoothed the data using:
>
> mri_surf2surf --hemi lh --s fsaverage --sval 
> Corr_CV_LGI/lh.vol.mgh --fwhm 10 --cortex --tval Corr_CV_LGI/lh.vol.10.mgh
> mri_surf2surf --hemi lh --s fsaverage --sval Corr_CV_LGI/lh.LGI.mgh 
> --fwhm 10 --cortex --tval Corr_CV_LGI/lh.LGI.10.mgh
>
> Finally I ran glmfit command as following:
>
> mri_glmfit --y Corr_CV_LGI/lh.vol.10.mgh --fsgd CV_LGI.fsgd dods --C 
> Corr-VL-cor.mtx --surf fsaverage lh --cortex --glmdir 
> Corr_CV_LGI/lh.VL.glmdir --pvr Corr_CV_LGI/lh.LGI.10.mgh
>
> My fsgd file looks like this:
> GroupDescriptorFile 1
> Class Male
> Class Female
> Variables Age
> Input        X001Male36
> InputX003Male29
> InputX004Male39
> etc.
>
> and my contrast file (Corr-VL-cor.mtx) is: 0 0.5 0.5 0 1 (I am 
> interested in regressing out the effect of age and gender).
>
> These steps do not give me any error but somehow (i) I do not get 
> pcc.mgh (partial correlation between volume and LGI measures) file and 
> (ii) sig.mgh file also does not seem correct.
>
> Could you please help me in figuring out the error or where I am doing 
> wrong?
>
> Thanks.
>
>
>
>
>
>
> On Fri, Apr 28, 2017 at 3:19 PM, Douglas N Greve 
> <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
>
>     To use the PVR, you need to create a stack of the measures that
>     you want
>     to use (eg, lGI). This will be the same size as the stack you want to
>     correlate with. Eg, if you use mris_preproc to create a thickness
>     stack,
>     you would use the same command to create the lGI stack. Create
>     your FSGD
>     file as normal, but when you create your contrast file, make sure
>     to add
>     a column to handle the per-vertex regressor. Eg, if you have two
>     groups,
>     then you would create a contrast [0 0 1] to test for the effect of the
>     PVR. When you run mri_glmfit, just add --pvr lgi.mgz
>
>
>
>     On 04/27/2017 06:13 PM, Martin Juneja wrote:
>     > Hi Dr. Greve,
>     >
>     > I did not find --help option very helpful here and also I could not
>     > find much help from the previous FreeSurfer posts. Could you please
>     > share more details here e.g. how to set up fsgd and contrast
>     file and
>     > how to run mri_glmfit command here (e.g. what inputs should be
>     > provided here?).
>     >
>     > I am basically interested in correlating volume and gyrification
>     > regressing out the effect of age and gender. I already have
>     > lh.pial_lgi and lh.volume files saved in 'surf' directory of
>     each subject.
>     >
>     > Thanks.
>     >
>     > On Thu, Apr 27, 2017 at 8:42 AM, Douglas N Greve
>     > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>     <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>>> wrote:
>     >
>     >     You have to use the --pvr option to mri_glmfit. Run it with
>     --help to
>     >     get more info and write back if you still have questions
>     >
>     >
>     >     On 04/26/2017 08:33 PM, Martin Juneja wrote:
>     >     > Hello FreeSurfer experts,
>     >     >
>     >     > I came across a paper:
>     >     >
>     >
>     http://www.sciencedirect.com/science/article/pii/S0166432815001837
>     <http://www.sciencedirect.com/science/article/pii/S0166432815001837>
>     >   
>      <http://www.sciencedirect.com/science/article/pii/S0166432815001837
>     <http://www.sciencedirect.com/science/article/pii/S0166432815001837>>
>     >     > where correlation maps between volume and gyrification are
>     reported.
>     >     >
>     >     > I am familiar with GLM in FreeSurfer i.e. correlating
>     behavioral
>     >     > measures with volume and gyrification but I was wondering
>     how to
>     >     > correlate structure measures with each other e.g. volume and
>     >     gyrification.
>     >     >
>     >     > I would really appreciate any help.
>     >     >
>     >     > Thanks.
>     >     >
>     >     >
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>     >     --
>     >     Douglas N. Greve, Ph.D.
>     >     MGH-NMR Center
>     > gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>     <mailto:gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>>
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>     --
>     Douglas N. Greve, Ph.D.
>     MGH-NMR Center
>     gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>     Phone Number: 617-724-2358 <tel:617-724-2358>
>     Fax: 617-726-7422 <tel:617-726-7422>
>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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