no, that is not normal, you must have done something wrong :(

On 05/09/2016 12:09 PM, Martin Juneja wrote:
> Hi Dr. Greve,
>
> Thanks for all your help.
> After displaying second level functional connectivity maps (actually 
> when I display subject-wise FC maps also), I tried to match the seed 
> region location on FC maps using tksurfer, I found that that at the 
> seed-region partial correlation coefficient (pcc) value is not 1 and 
> when I display sig.nii, at seed region, FC value is not signifiant. I 
> was wondering if that's normal and freesurfer ignores self 
> connectivity i.e. connectivity of seed region with itself or I did 
> something wrong.
>
> Thanks much !
>
> On Fri, May 6, 2016 at 4:37 PM, Douglas N Greve 
> <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
>
>     Yes, those are the right commands. That will give you the ces (the
>     regression coefficient). Typically, people use the pearson correlation
>     coefficient (pcc), but I have not seen many differences between
>     the two.
>
>     On 05/06/2016 05:13 PM, Martin Juneja wrote:
>     > Thanks a lot Dr. Greve.
>     >
>     > So as per your suggestion: I ran the command isxconcat-sess -sf
>     > sessidlist -analysis workmem.sm05.rh -contrast encode-v-base -o
>     > my-group -all-contrasts i.e.- without specifying -map argument. So
>     > this generates ces.nii.gz and vesvar.nii.gz in output folder
>     my-group.
>     > To get the significance level from 2nd level analysis, I ran
>     > mri_glmfit --y ces.nii.gz --wls cesvar.nii.gz --osgm--surface
>     > fsaverage lh--glmdir my-glm.wls --nii.gz
>     > This generates sig.nii.gz file. Could you please confirm once again,
>     > that's how group level significant function connectivity is
>     calculated
>     > from 1st level FC maps?
>     > Thanks a lot for all your help.
>     >
>     > On Fri, May 6, 2016 at 3:23 PM, Douglas N Greve
>     > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>     <mailto:gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>>> wrote:
>     >
>     >     You should not use the sig as that is the first level
>     significance. If
>     >     you pass that to the higher level, then the results will be
>     hard to
>     >     interpret. I think you'll want to use pcc or ces. Otherwise
>     looks ok.
>     >     doug
>     >
>     >     On 05/06/2016 12:03 PM, Martin Juneja wrote:
>     >     > Dear FS experts,
>     >     >
>     >     > I just finished calculating functional connectivity maps using
>     >     > FreeSurfer. I just want to confirm if the following steps
>     I used are
>     >     > correct:
>     >     >
>     >     > (1). I defined configured seed regions parameters using
>     >     fcseed-config
>     >     > command, say R01.config and R02.config and created seeds using
>     >     > fcseed-sess command to generate R01.dat and R02.dat files.
>     >     > (2). Created nuisance vaiables: wm.config and vcsf.config
>     files
>     >     using
>     >     > fcseed-config and -sess: this step is independent of seeds and
>     >     is done
>     >     > only once independent of seeds
>     >     > (3). For mkanalysis-sess command for each seed using
>     R0*.dat file, I
>     >     > used '-notask' argument because I am performing resting-state
>     >     analysis.
>     >     > (4). For subject level analysis, I used selxavg3 for each seed
>     >     > (5). For 2nd level analysis: isxconcat-sess -all-contrasts
>     -map
>     >     sig.nii.gz
>     >     >
>     >     > I can process all these steps without any error. If these
>     steps are
>     >     > correct, can some one please confirm again that for RSFC, I am
>     >     > correctly using -notask in step (3) and -all-contrast in
>     step (5).
>     >     > Also, in the instructions, it's mentioned to use -map pcc if
>     >     > interested in calculating partial correlation coefficient,
>     but I am
>     >     > interested in using sig to get group level significant
>     maps, would
>     >     > that be OK to use in this command as -map sig?
>     >     >
>     >     > Thanks for your help.
>     >     >
>     >     > Regards,
>     >     > MJ
>     >     >
>     >     >
>     >     > _______________________________________________
>     >     > Freesurfer mailing list
>     >     > Freesurfer@nmr.mgh.harvard.edu
>     <mailto:Freesurfer@nmr.mgh.harvard.edu>
>     >     <mailto:Freesurfer@nmr.mgh.harvard.edu
>     <mailto:Freesurfer@nmr.mgh.harvard.edu>>
>     >     >https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>     >
>     >     --
>     >     Douglas N. Greve, Ph.D.
>     >     MGH-NMR Center
>     > gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>     <mailto:gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>>
>     >     Phone Number: 617-724-2358 <tel:617-724-2358>
>     <tel:617-724-2358 <tel:617-724-2358>>
>     >     Fax: 617-726-7422 <tel:617-726-7422> <tel:617-726-7422
>     <tel:617-726-7422>>
>     >
>     >     Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>     <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
>     >     <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
>     >     FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
>     > www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>     <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>
>     >     <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>
>     >     Outgoing:
>     > ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>     >
>     >     _______________________________________________
>     >     Freesurfer mailing list
>     > Freesurfer@nmr.mgh.harvard.edu
>     <mailto:Freesurfer@nmr.mgh.harvard.edu>
>     <mailto:Freesurfer@nmr.mgh.harvard.edu
>     <mailto:Freesurfer@nmr.mgh.harvard.edu>>
>     > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>     >
>     >
>     >     The information in this e-mail is intended only for the
>     person to
>     >     whom it is
>     >     addressed. If you believe this e-mail was sent to you in
>     error and
>     >     the e-mail
>     >     contains patient information, please contact the Partners
>     >     Compliance HelpLine at
>     > http://www.partners.org/complianceline . If the e-mail was sent to
>     >     you in error
>     >     but does not contain patient information, please contact the
>     >     sender and properly
>     >     dispose of the e-mail.
>     >
>     >
>     >
>     >
>     > _______________________________________________
>     > Freesurfer mailing list
>     > Freesurfer@nmr.mgh.harvard.edu
>     <mailto:Freesurfer@nmr.mgh.harvard.edu>
>     > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>
>     --
>     Douglas N. Greve, Ph.D.
>     MGH-NMR Center
>     gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
>     Phone Number: 617-724-2358 <tel:617-724-2358>
>     Fax: 617-726-7422 <tel:617-726-7422>
>
>     Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>     <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
>     FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
>     www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>     <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>
>     Outgoing:
>     ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>
>     _______________________________________________
>     Freesurfer mailing list
>     Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu>
>     https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>
>
>
>
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

Reply via email to