If you want to display the group mean on the average anatomy of your 
group, then you use make_average_subject. This is different that just 
creating an average map of cortical thickness (as is done with 
mris_preproc). make_average_subject actually creates surfaces, the whole 
freesurfer subject tree, etc. mris_preproc just creates a single file.

doug

On 04/17/2014 03:18 PM, Jon Holt wrote:
> Doug
>
> thank you for your patience. for you what seems natural can be a bit 
> confusing for me. I'll do what you suggests, but I have to ask where does 
> make_average_subject come into play. you recommended it as an option, but now 
> it doesn't seem to be
> a part of the process
>
> Jon
>> On Apr 17, 2014, at 3:08 PM, Douglas N Greve <gr...@nmr.mgh.harvard.edu> 
>> wrote:
>>
>>
>> I'm a little lost here. Why would you run mris_preproc with the average 
>> subject as input? That is not one of the options I listed below. It sounds 
>> like you would run mris_preproc with fsaverage as the target and your list 
>> of subjects for a group as input. Then take the mean of the output stack to 
>> give you the group mean (mri_concat y.mgh --mean --o y.mean.mgh). Do this 
>> for each group. You can then display it on the average subject
>>
>> doug
>>
>>> On 04/17/2014 11:22 AM, Jonathan Holt wrote:
>>> Anyone have any input?
>>>> On Apr 16, 2014, at 11:27 AM, Jonathan Holt <whats...@umich.edu> wrote:
>>>>
>>>> Doug,
>>>>
>>>> Thanks for the quick reply.
>>>>
>>>> At this point all I want to do is calculate average thickness, per group, 
>>>> then visualize the average whole brain thickness for each group. I’m 
>>>> thinking I’m probably going to need the latter option, but to clarify when 
>>>> I’m going to run mris_preproc the target is fsaverage and by --s will be 
>>>> averagesubject?
>>>>
>>>> so
>>>>
>>>> mris_preproc --s averagesubject --target fsaverage --hemi ?h --meas 
>>>> thickness --out new_averagesubject
>>>>
>>>> ?
>>>>
>>>> jon
>>>>> On Apr 16, 2014, at 11:17 AM, Douglas N Greve <gr...@nmr.mgh.harvard.edu> 
>>>>> wrote:
>>>>>
>>>>> I'm not sure I understand what you mean. If you follow the group
>>>>> analysis wiki, it does not give you an option to even create an average
>>>>> subject, and you have to generate the average subject from
>>>>> make_average_subject. The proper path depends on what you want to do
>>>>> exactly.
>>>>>
>>>>> If you want to do a full analysis on an average subject, then you'll
>>>>> need to create the average subject with make_average_subject. Then you
>>>>> will need to register your individuals to this subject with surfreg --s
>>>>> individual --t averagesubject ... Then run mris_preproc with --target
>>>>> averagesubject --surfreg averagesubject.sphere.reg
>>>>>
>>>>> If you want to simply display the results on the average group anatomy,
>>>>> then run make_average_subject to create the average. Run mris_preproc
>>>>> using fsaverage. When you go to display the final result (eg, with
>>>>> tksurfer or freeview), specify the averagesubject instead of fsaverage
>>>>>
>>>>> doug
>>>>>
>>>>>> On 04/16/2014 11:03 AM, Jonathan Holt wrote:
>>>>>> Hi all,
>>>>>>
>>>>>> I’m currently trying to generate an average subject for two groups so 
>>>>>> that I might be able to display average thickness for both groups. I’m 
>>>>>> confused as to whether I should be following the GroupAnalysis workflow 
>>>>>> in the wiki, or if I should use make_average_subject and mris_preproc in 
>>>>>> tandem, but for the latter option (if it is the appropriate one) how 
>>>>>> should I use the two together, if that’s the right approach?
>>>>>>
>>>>>> jon
>>>>>> _______________________________________________
>>>>>> Freesurfer mailing list
>>>>>> Freesurfer@nmr.mgh.harvard.edu
>>>>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>>> -- 
>>>>> Douglas N. Greve, Ph.D.
>>>>> MGH-NMR Center
>>>>> gr...@nmr.mgh.harvard.edu
>>>>> Phone Number: 617-724-2358
>>>>> Fax: 617-726-7422
>>>>>
>>>>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>>>>> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
>>>>> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>>>>> Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>>>>>
>>>>> _______________________________________________
>>>>> Freesurfer mailing list
>>>>> Freesurfer@nmr.mgh.harvard.edu
>>>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>>>
>>>>>
>>>>> The information in this e-mail is intended only for the person to whom it 
>>>>> is
>>>>> addressed. If you believe this e-mail was sent to you in error and the 
>>>>> e-mail
>>>>> contains patient information, please contact the Partners Compliance 
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>> -- 
>> Douglas N. Greve, Ph.D.
>> MGH-NMR Center
>> gr...@nmr.mgh.harvard.edu
>> Phone Number: 617-724-2358
>> Fax: 617-726-7422
>>
>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
>> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>> Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>>
>

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

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