I'm a little lost here. Why would you run mris_preproc with the average 
subject as input? That is not one of the options I listed below. It 
sounds like you would run mris_preproc with fsaverage as the target and 
your list of subjects for a group as input. Then take the mean of the 
output stack to give you the group mean (mri_concat y.mgh --mean --o 
y.mean.mgh). Do this for each group. You can then display it on the 
average subject

doug

On 04/17/2014 11:22 AM, Jonathan Holt wrote:
> Anyone have any input?
> On Apr 16, 2014, at 11:27 AM, Jonathan Holt <whats...@umich.edu> wrote:
>
>> Doug,
>>
>> Thanks for the quick reply.
>>
>> At this point all I want to do is calculate average thickness, per group, 
>> then visualize the average whole brain thickness for each group. I’m 
>> thinking I’m probably going to need the latter option, but to clarify when 
>> I’m going to run mris_preproc the target is fsaverage and by --s will be 
>> averagesubject?
>>
>> so
>>
>> mris_preproc --s averagesubject --target fsaverage --hemi ?h --meas 
>> thickness --out new_averagesubject
>>
>> ?
>>
>> jon
>> On Apr 16, 2014, at 11:17 AM, Douglas N Greve <gr...@nmr.mgh.harvard.edu> 
>> wrote:
>>
>>> I'm not sure I understand what you mean. If you follow the group
>>> analysis wiki, it does not give you an option to even create an average
>>> subject, and you have to generate the average subject from
>>> make_average_subject. The proper path depends on what you want to do
>>> exactly.
>>>
>>> If you want to do a full analysis on an average subject, then you'll
>>> need to create the average subject with make_average_subject. Then you
>>> will need to register your individuals to this subject with surfreg --s
>>> individual --t averagesubject ... Then run mris_preproc with --target
>>> averagesubject --surfreg averagesubject.sphere.reg
>>>
>>> If you want to simply display the results on the average group anatomy,
>>> then run make_average_subject to create the average. Run mris_preproc
>>> using fsaverage. When you go to display the final result (eg, with
>>> tksurfer or freeview), specify the averagesubject instead of fsaverage
>>>
>>> doug
>>>
>>> On 04/16/2014 11:03 AM, Jonathan Holt wrote:
>>>> Hi all,
>>>>
>>>> I’m currently trying to generate an average subject for two groups so that 
>>>> I might be able to display average thickness for both groups. I’m confused 
>>>> as to whether I should be following the GroupAnalysis workflow in the 
>>>> wiki, or if I should use make_average_subject and mris_preproc in tandem, 
>>>> but for the latter option (if it is the appropriate one) how should I use 
>>>> the two together, if that’s the right approach?
>>>>
>>>> jon
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>>>>
>>>>
>>> -- 
>>> Douglas N. Greve, Ph.D.
>>> MGH-NMR Center
>>> gr...@nmr.mgh.harvard.edu
>>> Phone Number: 617-724-2358
>>> Fax: 617-726-7422
>>>
>>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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>>> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>>> Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>>>
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>
>

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

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