If you want to do a repeated measures ANOVA with more than two time 
points, I've put a page together here:

http://surfer.nmr.mgh.harvard.edu/fswiki/RepeatedMeasuresAnova

doug


On 10/15/2012 08:24 PM, Harry Hallock [hhal5...@uni.sydney.edu.au] wrote:
> Hi Martin,
>
> If you could make available that lme toolbox link, that would be great!
> Thanks for the help.
>
> Cheers,
> Harry
> ------------------------------------------------------------------------
> *From:* jorge luis [jbernal0...@yahoo.es]
> *Sent:* Tuesday, 16 October 2012 8:16 AM
> *To:* Martin Reuter; Harry Hallock [hhal5...@uni.sydney.edu.au]
> *Cc:* freesurfer@nmr.mgh.harvard.edu
> *Subject:* Mixed-effects models for longitudinal data analysis in 
> Freesurfer
>
> Hi Harry
>
> As Martin said, longitudinal linear mixed-effects models (lme) are the 
> recommended tool for analyzing longitudinal data obtained from the 
> Freesurfer longitudinal image processing pipeline. The increase in 
> power can be dramatic. Coming up there is a paper about this subject. 
> We are working on making our lme tools available and easy to use but 
> in the mean time, if you are interested, I can make available a link 
> for you to download our Matlab-based lme toolbox.
>
> Best
> -Jorge
>
>
>     ------------------------------------------------------------------------
>     *De:* Martin Reuter <mreu...@nmr.mgh.harvard.edu>
>     *Para:* Harry Hallock <hhal5...@uni.sydney.edu.au>; Douglas N
>     Greve <gr...@nmr.mgh.harvard.edu>;
>     "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
>     *Enviado:* Domingo 14 de octubre de 2012 21:06
>     *Asunto:* Re: [Freesurfer] 3 Factor glm group analysis
>
>     Hi Harry.
>
>     I have some scripts to compute a slope into the time thickness or
>     volume (linear fits) and then run a standard glm on that .
>
>     However, we recommend to run a linear mixed effects model
>     (external software). We are working on making that available.
>
>     Best Martin
>
>     Harry Hallock <hhal5...@uni.sydney.edu.au> wrote:
>
>         Thanks Doug!
>
>         If i wanted to add a third time-point, what would u suggest would be 
> a good method to use for time x group interaction?
>
>         Harry
>         
> ------------------------------------------------------------------------
>
>         From: freesurfer-boun...@nmr.mgh.harvard.edu 
> [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Douglas N Greve 
> [gr...@nmr.mgh.harvard.edu]
>         Sent: Wednesday, 10 October 2012 1:10 AM
>         To: freesurfer@nmr.mgh.harvard.edu
>         Subject: Re: [Freesurfer] 3 Factor glm group analysis
>
>         Hi Harry, I would do a time1-time2 subtraction (fscalc) and then do a 
> 2
>         group analysis (search for "paired" on our wiki).
>         doug
>
>
>
>         On 10/09/2012 12:45 AM, hhal5...@uni.sydney.edu.au wrote:
>
>             Hello, We are currently doing a longitudinal Group
>             Analysis using FreeSurfer, and were wondering if there is
>             a way to run a 3 factor design (time is 2 levels, group is
>             2 levels, subject is 10 levels) using the mri_glmfit
>             model, as i want to test the time by group interaction? Is
>             there a way of writing this model in an FSDG file? If we
>             can't do this using mri_glmfit, is it possible to do this
>             using QDEC? Regards, Harry
>             
> ------------------------------------------------------------------------
>             Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu
>             https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>
>
>         --
>         Douglas N. Greve, Ph.D.
>         MGH-NMR Center
>         gr...@nmr.mgh.harvard.edu
>         Phone Number: 617-724-2358
>         Fax: 617-726-7422
>
>         Bugs:surfer.nmr.mgh.harvard.edu/fswiki/BugReporting  
> <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
>         FileDrop:www.nmr.mgh.harvard.edu/facility/filedrop/index.html  
> <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>
>
>         
> ------------------------------------------------------------------------
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>         contains patient information, please contact the Partners Compliance 
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> ------------------------------------------------------------------------
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>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html

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