Hi Harry
As Martin said, longitudinal linear
mixed-effects models (lme) are the recommended tool for analyzing
longitudinal data obtained from the Freesurfer longitudinal image
processing pipeline. The increase in power can be dramatic. Coming
up there is a paper about this subject. We are working on making our
lme tools available and easy to use but in the mean time, if you are
interested, I
can make available a link for you to download our Matlab-based lme
toolbox.
Best
-Jorge
>________________________________
> De: Martin Reuter <mreu...@nmr.mgh.harvard.edu>
>Para: Harry Hallock <hhal5...@uni.sydney.edu.au>; Douglas N Greve
><gr...@nmr.mgh.harvard.edu>; "freesurfer@nmr.mgh.harvard.edu"
><freesurfer@nmr.mgh.harvard.edu>
>Enviado: Domingo 14 de octubre de 2012 21:06
>Asunto: Re: [Freesurfer] 3 Factor glm group analysis
>
>
>Hi Harry.
>
>I have some scripts to compute a slope into the time thickness or volume
>(linear fits) and then run a standard glm on that .
>
>However, we recommend to run a linear mixed effects model (external software).
>We are working on making that available.
>
>Best Martin
>
>
>Harry Hallock <hhal5...@uni.sydney.edu.au> wrote:
>Thanks Doug!
>>
>>If i wanted to add a third time-point, what would u suggest would be a good
>>method to use for time x group interaction?
>>
>>Harry
>>>>________________________________
>>
>>From: freesurfer-boun...@nmr.mgh.harvard.edu
>>[freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Douglas N Greve
>>[gr...@nmr.mgh.harvard.edu]
>>Sent: Wednesday, 10 October 2012 1:10 AM
>>To: freesurfer@nmr.mgh.harvard.edu
>>Subject: Re: [Freesurfer] 3 Factor glm group analysis
>>
>>Hi Harry, I would do a time1-time2 subtraction (fscalc) and then do a 2
>>group analysis (search for "paired" on our wiki).
>>doug
>>
>>
>>
>>On 10/09/2012 12:45 AM, hhal5...@uni.sydney.edu.au wrote:
>>
>>Hello,
>>>
>>>We are currently doing a longitudinal Group Analysis using
FreeSurfer,
>>>and were wondering if there is a way to run a 3 factor design (time is
>>>2 levels, group is 2 levels, subject is 10 levels) using the
>>>mri_glmfit model, as i want to test the time by group interaction? Is
>>>there a way of writing this model in an FSDG file? If we can't do this
>>>using mri_glmfit, is it possible to do this using QDEC?
>>>
>>>Regards,
>>>Harry
>>>
>>>
>>>
>>>
>>>>>>________________________________
>>>
>>>Freesurfer mailing list
>>>Freesurfer@nmr.mgh.harvard.edu
>>>https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>--
>>Douglas N. Greve, Ph.D.
>>MGH-NMR Center
>>gr...@nmr.mgh.harvard.edu
>>Phone Number: 617-724-2358
>>Fax: 617-726-7422
>>
>>Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>>FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>>
>>>>________________________________
>>
>>Freesurfer mailing list
>>Freesurfer@nmr.mgh.harvard.edu
>>https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>
>>
>>The information in this e-mail is intended only for the person to whom it is
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>>contains patient information, please contact the Partners Compliance HelpLine
>>at
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>>
>>
>>
>>>>________________________________
>>
>>Freesurfer mailing list
>>Freesurfer@nmr.mgh.harvard.edu
>>https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>
>>
>>
>--
>Sent from my phone, please excuse brevity.
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