thanks Bruce :)
-Mojdeh

On 07/20/2012 04:27 PM, Bruce Fischl wrote:
> Hi Mojdeh
>
> it's really hard to say how much you should correct. In general we 
> don't do that much.  A couple of control points or a few voxels added 
> to the wm.mgz can have a big effect if you are experienced. Mostly 
> just see if the ?h.white and pial surface are visually accurate, and 
> if not see if some small intervention might fix them.
>
> cheers
> Bruce
>
>
>
> On Fri, 20 Jul 2012, Mojdeh Zamyadi wrote:
>
>> Hi Bruce,
>>
>> Thank's for the reply! I'm not concerned about hippocampal volume for 
>> now, mostly needing cortical thickness for my project! Yes, I am 
>> using v5.1. So in case of cortical thickness I shouldn't worry too 
>> much about Talairach registration? could you please tell me what are 
>> the main things I should check and pay attention to for cortical 
>> thickness? I'm following the troubleshooting page 
>> (http://surfer.nmr.mgh.harvard.edu/fswiki/RecommendedReconstruction) 
>> and I see some discrepancies in the pial/WM surfaces but again I am 
>> not sure how much I should correct!
>>
>> Thanks again,
>> -Mojdeh
>>
>> On 07/20/2012 04:15 PM, Bruce Fischl wrote:
>>> Hi Mojdeh
>>>
>>> it won't affect any individual thickness measures, *but* will affect 
>>> the estimated total intracranial volume (eTIV). We don't typically 
>>> use eTIV for thickness correction, but do for things like 
>>> hippocampal volume. Are you using version 5.1? If so, that's the 
>>> problem. Nick has a fix for this that he can direct you about, or 
>>> you can wait for 5.2 and rerun the Talairach registration then.
>>>
>>> cheers
>>> Bruce
>>>
>>>
>>> On Fri, 20 Jul 2012, Mojdeh Zamyadi wrote:
>>>
>>>> Hi all,
>>>>
>>>> Sorry for re-posting this but it seems it didn't get through!
>>>>
>>>> I've just started to do cortical thickness analysis on some 
>>>> subjects and
>>>> I'm noticing some miss-registrations, more specifically the Talairach
>>>> image is smaller than the target image no matter what subject I 
>>>> look at!
>>>> I just wanted to make sure if this is something normal and to what
>>>> extend it's going to effect the individual cortical thickness
>>>> calculations. I guess I'm not sure how the Talairach transformation is
>>>> used in further steps of the cortical thickness calculation.
>>>>
>>>> I tried to attach example coronal, sagittal and horizontal slices 
>>>> of one
>>>> of my subjects but apparently it was too big for the mailing list. 
>>>> Pleas
>>>> let me know if there is a way to attach images here.
>>>>
>>>> I greatly appreciate your advice.
>>>>
>>>> Thanks,
>>>> Mojdeh Zamyadi, MSc
>>>> Clinical Research Project Assistant
>>>> The Hospital for Sick Children
>>>> 555 University Avenue
>>>> Toronto, ON, M5G 1X8
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>>>>
>>>>
>>>
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