Hi Joana,

no, what you did is fine. I just wanted to make sure that you are using
the cross table created from the long table (so that there is only a
single entry for each subject). It looks like that is the case.

Best, Martin

On Tue, 2011-09-27 at 12:11 +0200, Joana Braga Pereira wrote:
> Hi Martin,
> 
> 
> Many thanks for your reply!
> 
> 
> I did follow all the steps as described in the wiki.
> 
> 
> I'm not sure i understand your suggestion though..
> 
> 
> Are you proposing that, instead of using the cross.qdec.table, i
> should use the longitudinal table to see the difference between two
> time points? 
> 
> 
> My long.qdec.table looks like this:
> 
> 
> fsid         fsid-base         years 
> M_b01_pre template_M_b01 0 
> M_b01_post template_M_b01 1.33 
> M_b02_pre template_M_b02 0 
> M_b02_post template_M_b02 1.33 
> M_b03_pre template_b03 0 
> M_b03_post template_b03 1.42 
> M_b04_pre template_b04 0 
> M_b04_post template_b04 1.58 
> M_b05_pre template_b05 0 
> M_b05_post template_b05 1.83 
> M_b07_pre template_b07 0 
> M_b07_post template_b07 1.33 
> M_b09_pre template_b09 0 
> M_b09_post template_b09 1.25 
> M_b10_pre template_b10 0 
> M_b10_post template_b10 1.25 
> M_b11_pre template_b11 0 
> M_b11_post template_b11 1.42 
> M_b13_pre template_b13 0 
> M_b13_post template_b13 2.08 
> M_b14_pre template_b14 0 
> M_b14_post template_b14 1.42 
> M_b15_pre template_b15 0 
> M_b15_post template_b15 1.33 
> M_b16_pre template_b16 0 
> M_b16_post template_b16 1.67 
> M_b17_pre template_b17 0 
> M_b17_post template_b17 1.33 
> M_b18_pre template_b18 0 
> M_b18_post template_b18 1.25 
> M_b19_pre template_M_b19 0 
> M_b19_post template_M_b19 1.42 
> M_b20_pre template_M_b20 0 
> M_b20_post template_M_b20 1.25 
> M_b21_pre template_b21 0 
> M_b21_post template_b21 1.42 
> M_b22_pre template_b22 0 
> M_b22_post template_b22 1.17
> 
> 
> If i did that, qdec won't find long.thickness-rate...This measure as
> well as the other longitudinal measures (pc1, spc, etc) can only be
> found in the surf subfolders of the templates (fsid-base).
> 
> 
> What did i miss?
> 
> 
> Thanks for your patience,
> 
> 
> Joana
> 
> 
> 
> 
> 
> 2011/9/23 Martin Reuter <mreu...@nmr.mgh.harvard.edu>
>         Hi Joana,
>         
>         actually it is possible, when using long_mris_slopes after
>         running your
>         longitudinal data (I think that is what you did).
>         
>         I cannot judge if your table is correct. You did create that
>         table from
>         the longitudinal qdec table as described on the wiki
>         (longitudinal
>         tutorial) right?
>         So each line should be a template/base name and in the
>         longitudinal
>         table there should be two entries for each of these templates.
>         
>         I notice that the years (here the average, so probably the
>         distance in
>         time between your two time points) differs a lot (half a year
>         to a year)
>         between subjects, that is of course not optimal.
>         
>         You can look at different things:
>         
>         difference per year (rate)
>         percent change per year with respect to baseline (pc1)
>         or percent change per year with respect to average thickness
>         (spc,
>         called symmetrized percent change as it is symmetric).
>         
>         If you are interested in the change per year,
>         long_thickness_rate is
>         correct. It accounts for the different time intervals.
>         You can then (in qdec) check if this is measure is different
>         from zero.
>         
>         So everything you describe looks good.
>         
>         Best, Martin
>         
>         
>         
>         On Fri, 2011-09-23 at 11:25 -0400, Douglas N Greve wrote:
>         > This is actually something that you cannot currently do in
>         QDEC. Try
>         > doing a search for "paired" on our wiki for instructions on
>         how to do
>         > this type of analysis.
>         > doug
>         >
>         > Joana Braga Pereira wrote:
>         > > Dear Freesurfers,
>         > >
>         > > I'm doing a longitudinal analysis of cortical thickness
>         using the
>         > > newest version of Freesurfer and there is something i
>         would like to
>         > > ask you all.
>         > >
>         > > I have two time points and only one group of patients.
>         > >
>         > > I've finished the pre-processing and am now searching for
>         differences
>         > > between the two time points using Qdec.
>         > >
>         > > Since i only have one group my cross.qdec.table.dat file
>         looks pretty
>         > > much like this:
>         > >
>         > > fsid         years
>         > > template_M_b01 0.665
>         > > template_M_b02 0.665
>         > > template_b03        0.71
>         > > template_b04        0.79
>         > > template_b05        0.915
>         > > template_b07 0.665
>         > > template_b09 0.625
>         > > template_b10 0.625
>         > > template_b11 0.71
>         > > template_b13 1.04
>         > > template_b14 0.71
>         > > template_b15 0.665
>         > > template_b16 0.835
>         > > template_b17 0.665
>         > > template_b18 0.625
>         > > template_M_b19 0.71
>         > > template_M_b20 0.625
>         > > template_b21 0.71
>         > > template_b22 0.585
>         > >
>         > > I selected the long.thickness.rate in Qdec interface and
>         years as
>         > > continuous covariate since it is the only variable that i
>         have in
>         > > my cross.qdec.table.dat (no groups or other covariates of
>         interest).
>         > >
>         > > My question is: Is this the analysis i should be doing
>         given that i
>         > > want to know the differences between time point 1 - time
>         point 2?
>         > >
>         > > Many thanks,
>         > >
>         > > Joana
>         > >
>         
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