Hi Martin,

Many thanks for your reply!

I did follow all the steps as described in the wiki.

I'm not sure i understand your suggestion though..

Are you proposing that, instead of using the cross.qdec.table, i should use
the longitudinal table to see the difference between two time points?

My long.qdec.table looks like this:

fsid         fsid-base         years
M_b01_pre template_M_b01 0
M_b01_post template_M_b01 1.33
M_b02_pre template_M_b02 0
M_b02_post template_M_b02 1.33
M_b03_pre template_b03 0
M_b03_post template_b03 1.42
M_b04_pre template_b04 0
M_b04_post template_b04 1.58
M_b05_pre template_b05 0
M_b05_post template_b05 1.83
M_b07_pre template_b07 0
M_b07_post template_b07 1.33
M_b09_pre template_b09 0
M_b09_post template_b09 1.25
M_b10_pre template_b10 0
M_b10_post template_b10 1.25
M_b11_pre template_b11 0
M_b11_post template_b11 1.42
M_b13_pre template_b13 0
M_b13_post template_b13 2.08
M_b14_pre template_b14 0
M_b14_post template_b14 1.42
M_b15_pre template_b15 0
M_b15_post template_b15 1.33
M_b16_pre template_b16 0
M_b16_post template_b16 1.67
M_b17_pre template_b17 0
M_b17_post template_b17 1.33
M_b18_pre template_b18 0
M_b18_post template_b18 1.25
M_b19_pre template_M_b19 0
M_b19_post template_M_b19 1.42
M_b20_pre template_M_b20 0
M_b20_post template_M_b20 1.25
M_b21_pre template_b21 0
M_b21_post template_b21 1.42
M_b22_pre template_b22 0
M_b22_post template_b22 1.17

If i did that, qdec won't find long.thickness-rate...This measure as well as
the other longitudinal measures (pc1, spc, etc) can only be found in the
surf subfolders of the templates (fsid-base).

What did i miss?

Thanks for your patience,

Joana



2011/9/23 Martin Reuter <mreu...@nmr.mgh.harvard.edu>

> Hi Joana,
>
> actually it is possible, when using long_mris_slopes after running your
> longitudinal data (I think that is what you did).
>
> I cannot judge if your table is correct. You did create that table from
> the longitudinal qdec table as described on the wiki (longitudinal
> tutorial) right?
> So each line should be a template/base name and in the longitudinal
> table there should be two entries for each of these templates.
>
> I notice that the years (here the average, so probably the distance in
> time between your two time points) differs a lot (half a year to a year)
> between subjects, that is of course not optimal.
>
> You can look at different things:
>
> difference per year (rate)
> percent change per year with respect to baseline (pc1)
> or percent change per year with respect to average thickness (spc,
> called symmetrized percent change as it is symmetric).
>
> If you are interested in the change per year, long_thickness_rate is
> correct. It accounts for the different time intervals.
> You can then (in qdec) check if this is measure is different from zero.
>
> So everything you describe looks good.
>
> Best, Martin
>
>
> On Fri, 2011-09-23 at 11:25 -0400, Douglas N Greve wrote:
> > This is actually something that you cannot currently do in QDEC. Try
> > doing a search for "paired" on our wiki for instructions on how to do
> > this type of analysis.
> > doug
> >
> > Joana Braga Pereira wrote:
> > > Dear Freesurfers,
> > >
> > > I'm doing a longitudinal analysis of cortical thickness using the
> > > newest version of Freesurfer and there is something i would like to
> > > ask you all.
> > >
> > > I have two time points and only one group of patients.
> > >
> > > I've finished the pre-processing and am now searching for differences
> > > between the two time points using Qdec.
> > >
> > > Since i only have one group my cross.qdec.table.dat file looks pretty
> > > much like this:
> > >
> > > fsid         years
> > > template_M_b01 0.665
> > > template_M_b02 0.665
> > > template_b03        0.71
> > > template_b04        0.79
> > > template_b05        0.915
> > > template_b07 0.665
> > > template_b09 0.625
> > > template_b10 0.625
> > > template_b11 0.71
> > > template_b13 1.04
> > > template_b14 0.71
> > > template_b15 0.665
> > > template_b16 0.835
> > > template_b17 0.665
> > > template_b18 0.625
> > > template_M_b19 0.71
> > > template_M_b20 0.625
> > > template_b21 0.71
> > > template_b22 0.585
> > >
> > > I selected the long.thickness.rate in Qdec interface and years as
> > > continuous covariate since it is the only variable that i have in
> > > my cross.qdec.table.dat (no groups or other covariates of interest).
> > >
> > > My question is: Is this the analysis i should be doing given that i
> > > want to know the differences between time point 1 - time point 2?
> > >
> > > Many thanks,
> > >
> > > Joana
> > >
> ------------------------------------------------------------------------
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>
>
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