it's not necssarily less, as voxels that are not labeled part of the 
structure may contain some volume as well (e.g. ventricular voxels 
containing some hippocampus)
On Mon, 15 Feb 2010, Hui J Yu wrote:

> Thank you for the quick response.  If you do a partial volume correction, I 
> would think the volumes from freesurfer would be less than simply counting 
> all voxels, but it seems to be the opposite.  Any thoughts?
>
> ----- Original Message -----
> From: Bruce Fischl <fis...@nmr.mgh.harvard.edu>
> Date: Monday, February 15, 2010 10:42 am
> Subject: Re: [Freesurfer] Subcortical Volume Calculation
> To: Hui J Yu <h...@ic.sunysb.edu>
> Cc: freesurfer@nmr.mgh.harvard.edu
>
>> yes, we do a partial volume correction of the volumes,
>> accounting for the fraction of the structure in each border voxel.
>>
>> cheers
>> Bruce
>> On Mon, 15 Feb 2010, Hui J Yu wrote:
>>
>>> Dear Freesurfer users,
>>>
>>> I am wondering how are the volumes calculated from stats such
>> aseg.stat.  When I export the aseg and do a voxel count and
>> multiple the volume per voxel, my total volume is different from
>> that is given by the stats.  For example, the hippocampal
>> volume given by aseg.stats for one of my controls is 4000 cm3,
>> but when I export the aseg.mgz into matlab and do a voxel count
>> (my original voxel volume is 1mm3 isotropic) for that labeled
>> mask, the total volume is aorund 3000 cm3.  Does freesurfer
>> does some sort of intensity normalization or partial volume
>> correction?  Even if so, the magnitude of difference is
>> large that I am puzzled.
>>>
>>> Thank you very much.
>>>
>>>
>>>
>
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