Sorry, it did fall thru the cr cks. Can you try running it with --no-adjust? When you give it a sign (ie, --pos), it assumes that the input values and threshold are -log10(p) and then adjusts the threshold for a single-tailed (signed) test, which means that it subtracts log10(2) = 0.3 from the threshold. So it's really using 0.5-0.3=0.2 as the threshold. Hope that made sense ...

doug


Emily Cooper wrote:

hi,

sorry to bother the mailinglist again, but i haven't received a response to this question. i just wanted to make sure that it hadn't slipped through the cracks. any help would be very much appreciated,

emily

On 6/1/07, Emily Cooper <[EMAIL PROTECTED] <mailto:[EMAIL PROTECTED]>> wrote:

    hi,

    i am having a strange problem with mri_surfcluster.

    i give it the following command line:
    mri_surfcluster --in
    
/disks/gpfs/fmri/emily.permutations/correlation.permutations/perm.mghs/2.lh.ccf.perm.smooth6.mgh
    --subject fsaverage --hemi lh --thmin 0.5 --thmax 1.0 --sign pos
    --minarea 6 --sum
    
/disks/gpfs/fmri/emily.permutations/correlation.permutations/perm.clusters/2.ccf.pos.output.sum.txt

    and i get this result in the summary:
    # Cluster Growing Summary (mri_surfcluster )
    # $Id: mri_surfcluster.c,v 1.26.2.4 <http://1.26.2.4> 2006/07/13
    17:50:28 greve Exp $
    # $Id: mrisurf.c,v 1.441.2.5 2006/11/29 20:28:16 nicks Exp $
    # CreationTime 2007/06/01-19:04:15-GMT
    # cmdline mri_surfcluster --in
    
/disks/gpfs/fmri/emily.permutations/correlation.permutations/perm.mghs/2.lh.ccf.perm.smooth6.mgh
    --subject fsaverage --hemi lh --thmin 0.5 --thmax 1.0 --sign pos
    --minarea 6 --sum
    
/disks/gpfs/fmri/emily.permutations/correlation.permutations/perm.clusters/2.ccf.pos.output.sum.txt
    # cwd /disks/gpfs/fmri/emily.permutations/correlation.permutations
    # sysname  Linux
    # hostname andrew.bsd.uchicago.edu <http://andrew.bsd.uchicago.edu>
    # machine  i686
    # FixVertexAreaFlag = 1
    #
# Input /disks/gpfs/fmri/emily.permutations/correlation.permutations/perm.mghs/2.lh.ccf.perm.smooth6.mgh

    # Frame Number      0
    # srcsubj fsaverage
    # hemi lh
    # surface white
    # SUBJECTS_DIR /home/ecooper/subjects
    # Minimum Threshold 0.5
    # Maximum Threshold 1
    # Threshold Sign    pos
    # AdjustThreshWhenOneTail 1
    # Area Threshold    6 mm^2
    # Overall max 0.632052 at vertex 5494
    # Overall min 0.12689 at vertex 750
    # NClusters          2
    # Total Cortical Surface Area 70394.7 (mm^2)
    # FixMNI = 1
    #
    # ClusterNo  Max   VtxMax   Size(mm^2)  TalX   TalY   TalZ    NVtxs
       1        0.632    5494  85426.29    -50.2  -16.0   -7.2  161181
       2        0.223    9300     23.61    -31.7  -26.7    9.9    68


    the problem is that this is just entirely incorrect. when i view
    the input dataset in tksurfer, it's clear just from scanning over
    the vertices that 161181 out of 163842 total of them do not have
    intensity values between .5 and 1 (thmin and thmx), let alone in a
    giant cluster together. furthermore, when i make a historgram of a
    text file containing these intensity values, it shows that the
    majority of them are less than .5, and thus shouldn't be
    recognized as part of a cluster based on my specifications in the
    mri_surfcluster command:

    $breaks
[1] -0.10 -0.05 0.00 0.05 0.10 0.15 0.20 0.25 0.30 0.35 0.40 0.45
    [13]  0.50  0.55  0.60  0.65  0.70  0.75  0.80  0.85  0.90  0.95  1.00

    $counts
     [1]    10   205  1320  3881  7834 12333 16777 20168 21369 20405
    17219 13789
    [13] 10453  7479  4897  2988  1599   737   283    81    14     1

    $intensities
     [1] 0.0012206880 0.0250241086 0.1611308456 0.4737490997 0.9562871547
     [6] 1.5054747867 2.0479486334 2.4618840102 2.6084886659 2.4908143211
    [11] 2.1019030529 1.6832069921 1.2759854006 0.9129527227 0.5977710233
    [16] 0.3647416413 0.1951880470 0.0899647221 0.0345454767 0.0098875746
    [21] 0.0017089635 0.0001220688

    $density
     [1] 0.0012206880 0.0250241086 0.1611308456 0.4737490997 0.9562871547
     [6] 1.5054747867 2.0479486334 2.4618840102 2.6084886659 2.4908143211
    [11] 2.1019030529 1.6832069921 1.2759854006 0.9129527227 0.5977710233
    [16] 0.3647416413 0.1951880470 0.0899647221 0.0345454767 0.0098875746
    [21] 0.0017089635 0.0001220688

    $mids
[1] -0.075 -0.025 0.025 0.075 0.125 0.175 0.225 0.275 0.325 0.375 [11] 0.425 0.475 0.525 0.575 0.625 0.675 0.725 0.775 0.825 0.875
    [21]  0.925  0.975

    any ideas as to what is going wrong here? am i using the thmin and
    thmax flags wrong?

    thanks so much,
    emily


------------------------------------------------------------------------

_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer


--
Douglas N. Greve, Ph.D.
MGH-NMR Center
[EMAIL PROTECTED]
Phone Number: 617-724-2358 Fax: 617-726-7422

In order to help us help you, please follow the steps in:
surfer.nmr.mgh.harvard.edu/fswiki/BugReporting


_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

Reply via email to