thanks so much! that seems to have done the trick,

emily

On 6/4/07, Doug Greve <[EMAIL PROTECTED]> wrote:


Sorry, it did fall thru the cr cks. Can you try running it with
--no-adjust? When you give it a sign (ie, --pos), it assumes that the input
values and threshold are -log10(p) and then adjusts the threshold for a
single-tailed (signed) test, which means that it subtracts log10(2) = 0.3from 
the threshold. So it's really using
0.5-0.3=0.2 as the threshold. Hope that made sense ...

doug


Emily Cooper wrote:

hi,

sorry to bother the mailinglist again, but i haven't received a response
to this question. i just wanted to make sure that it hadn't slipped through
the cracks. any help would be very much appreciated,

emily

On 6/1/07, Emily Cooper <[EMAIL PROTECTED]> wrote:
>
> hi,
>
> i am having a strange problem with mri_surfcluster.
>
> i give it the following command line:
> mri_surfcluster --in
> 
/disks/gpfs/fmri/emily.permutations/correlation.permutations/perm.mghs/2.lh.ccf.perm.smooth6.mgh
> --subject fsaverage --hemi lh --thmin 0.5 --thmax 1.0 --sign pos
> --minarea 6 --sum
> 
/disks/gpfs/fmri/emily.permutations/correlation.permutations/perm.clusters/2.ccf.pos.output.sum.txt
>
> and i get this result in the summary:
> # Cluster Growing Summary (mri_surfcluster )
> # $Id: mri_surfcluster.c,v 1.26.2.4 2006/07/13 17:50:28 greve Exp $
> # $Id: mrisurf.c,v 1.441.2.5 2006/11/29 20:28:16 nicks Exp $
> # CreationTime 2007/06/01-19:04:15-GMT
> # cmdline mri_surfcluster --in
> 
/disks/gpfs/fmri/emily.permutations/correlation.permutations/perm.mghs/2.lh.ccf.perm.smooth6.mgh
> --subject fsaverage --hemi lh --thmin 0.5 --thmax 1.0 --sign pos
> --minarea 6 --sum
> 
/disks/gpfs/fmri/emily.permutations/correlation.permutations/perm.clusters/2.ccf.pos.output.sum.txt
> # cwd /disks/gpfs/fmri/emily.permutations/correlation.permutations
> # sysname  Linux
> # hostname andrew.bsd.uchicago.edu
> # machine  i686
> # FixVertexAreaFlag = 1
> #
> # Input
> 
/disks/gpfs/fmri/emily.permutations/correlation.permutations/perm.mghs/2.lh.ccf.perm.smooth6.mgh
>
> # Frame Number      0
> # srcsubj fsaverage
> # hemi lh
> # surface white
> # SUBJECTS_DIR /home/ecooper/subjects
> # Minimum Threshold 0.5
> # Maximum Threshold 1
> # Threshold Sign    pos
> # AdjustThreshWhenOneTail 1
> # Area Threshold    6 mm^2
> # Overall max 0.632052 at vertex 5494
> # Overall min 0.12689 at vertex 750
> # NClusters          2
> # Total Cortical Surface Area 70394.7 (mm^2)
> # FixMNI = 1
> #
> # ClusterNo  Max   VtxMax   Size(mm^2)  TalX   TalY   TalZ    NVtxs
>    1        0.632    5494  85426.29    -50.2  -16.0   -7.2  161181
>    2        0.223    9300     23.61    -31.7  -26.7    9.9    68
>
>
> the problem is that this is just entirely incorrect. when i view the
> input dataset in tksurfer, it's clear just from scanning over the vertices
> that 161181 out of 163842 total of them do not have intensity values between
> .5 and 1 (thmin and thmx), let alone in a giant cluster together.
> furthermore, when i make a historgram of a text file containing these
> intensity values, it shows that the majority of them are less than .5, and
> thus shouldn't be recognized as part of a cluster based on my specifications
> in the mri_surfcluster command:
>
> $breaks
>  [1] -0.10 -0.05  0.00  0.05  0.10  0.15  0.20  0.25  0.30  0.35  0.40
> 0.45
> [13]  0.50  0.55  0.60  0.65  0.70  0.75  0.80  0.85  0.90  0.95  1.00
>
> $counts
>  [1]    10   205  1320  3881  7834 12333 16777 20168 21369 20405 17219
> 13789
> [13] 10453  7479  4897  2988  1599   737   283    81    14     1
>
> $intensities
>  [1] 0.0012206880 0.0250241086 0.1611308456 0.4737490997 0.9562871547
>  [6] 1.5054747867 2.0479486334 2.4618840102 2.6084886659 2.4908143211
> [11] 2.1019030529 1.6832069921 1.2759854006 0.9129527227 0.5977710233
> [16] 0.3647416413 0.1951880470 0.0899647221 0.0345454767 0.0098875746
> [21] 0.0017089635 0.0001220688
>
> $density
>  [1] 0.0012206880 0.0250241086 0.1611308456 0.4737490997 0.9562871547
>  [6] 1.5054747867 2.0479486334 2.4618840102 2.6084886659 2.4908143211
> [11] 2.1019030529 1.6832069921 1.2759854006 0.9129527227 0.5977710233
> [16] 0.3647416413 0.1951880470 0.0899647221 0.0345454767 0.0098875746
> [21] 0.0017089635 0.0001220688
>
> $mids
>  [1] -0.075 -0.025  0.025  0.075  0.125  0.175  0.225  0.275  0.325
> 0.375
> [11]  0.425  0.475  0.525  0.575  0.625  0.675  0.725   0.775  0.825
> 0.875
> [21]  0.925  0.975
>
> any ideas as to what is going wrong here? am i using the thmin and thmax
> flags wrong?
>
> thanks so much,
> emily
>
>
------------------------------

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--
Douglas N. Greve, Ph.D.
MGH-NMR Center
[EMAIL PROTECTED]
Phone Number: 617-724-2358
Fax: 617-726-7422

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