Dear Abhishek, To me, it looks like an alternative conformation of the peptide chain or maybe even a conformational change with respect to the starting model. The peptide chain does not look too well defined, despite high resolution electron density.
Best, Herman Von: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] Im Auftrag von Abhishek Anan Gesendet: Freitag, 3. November 2017 09:26 An: CCP4BB@JISCMAIL.AC.UK Betreff: [EXTERNAL] [ccp4bb] another unknown density problem Hi all, I have an "unknown" density in the map. I have tried to fit it to PEG but it doesn't fit very well. I was wondering if there are other PEG-related or other molecules I could try. The crystal grew in TRIS-HCl and PEG MME 2K. Thank you Abhishek