*Postgraduate Studentship available in the Ciulli Laboratory* *Chemical & Structural Biology of Protein-Protein Interactions*
A fully-funded PhD studentship is available immediately in our new laboratory within the College of Life Sciences at the University of Dundee ( http://www.lifesci.dundee.ac.uk/people/alessio-ciulli) to investigate the Chemical & Structural Biology of protein-protein interfaces (PPIs) that recognise post-translational modifications of protein amino acids. This multi-disciplinary project will comprise structure-function studies of PPIs and protein-ligand interactions using a combination of molecular/structural biology and biophysical techniques with small molecule drug design and organic synthesis. The goals of the project are two-fold: 1) to elucidate structure-function relationships within multidomain proteins containing paired chromatin reader domains that act as epigenetics effectors; 2) to exploit this information towards designing and developing novel small molecule chemical probes that modulate these PPIs. For a recent example of our research on PPIs see Van Molle et al. *Chemistry & Biology* *2012*, 19, 1300-12 (doi<http://dx.doi.org/10.1016/j.chembiol.2012.08.015> ) Applicants should have (or expect to obtain) at least the equivalent of a UK II.1 honours degree (and preferably a Masters) in chemistry, biochemistry, chemical biology, structural biology or other relevant discipline. Applications from students with either a strong chemical or biological science background are encouraged, where the applicant is interested in learning the other discipline. To apply please complete the online application form at: http://www.lifesci.dundee.ac.uk/phdprog/division-biological-chemistry-and-drug-discovery/dr-alessio-ciulli Please do not hesitate to contact me by email for informal enquiries or if you want to discuss the project further. ------------------------------------------------------------------------------ Alessio Ciulli, PhD Reader in Chemical and Structural Biology BBSRC David Phillips Fellow Division: Biological Chemistry and Drug Discovery College of Life Sciences, University of Dundee, Dundee Email: a.ciu...@dundee.ac.uk Email: ac...@cam.ac.uk http://www.lifesci.dundee.ac.uk/people/alessio-ciulli http://www-ciulli.ch.cam.ac.uk/ ------------------------------------------------------------------------------ The University of Dundee is a registered Scottish Charity, No: SC015096
