On Tue, Jul 12, 2011 at 6:08 PM, Jiamu Du <jiam...@gmail.com> wrote: > I am now working on a low resolution phase determination (around 3.3 A with > Se anomalous signal around 3.8 A). > I can find the Se site and get the phase, but the density map is not so > good. > Some part of the protein (about 1/3) has a homologue model which is also > can be found using Phaser. The homologue region has a good map while other > region only show a poor map. > I think the combination of experimental phase and MR phase might improve > the map. Is there anybody can help find which program can work on this? >
Phaser has been able to do this for years - you need to run it in experimental phasing mode, but include the MR solution as a partial model. -Nat
