Dear Sergei, Did you check the "mean intensity as function of spindle position" statistics in the CORRECT.LP file? Any (even minute) shutter problems will affect these thin frames significantly. If this is indeed the problem, you could then try to set:
PATCH_SHUTTER_PROBLEM=TRUE for the CORRECT stage in XDS. Cheers, Martin On Nov 5, 2010, at 9:40 AM, Sergei Strelkov wrote: > Dear All, > > I am processing a dataset collected (not by me) with 0.1 degree oscillations. > The diffraction is quite weak even though there is a clean diffraction > pattern to about 3A. > > Either Mosflm or XDS processes the data readily with +/- default settings > but both yield a high overall Rmerge of about 0.23 in the expected symmetry. > Processing in P1 yields an overall Rmerge of ~0.18, but what is especially > disappointing > is that Rmerge is as high as 0.15 at ~5A resolution already. > > The question is, how can we process the data so that the merging statistics > becomes more reasonable? > > Apparent mosaicity turns out to be ~0.5A. My naive way of thinking is > to try treating each five consecutive frames as a single 0.5 degree frame. > Does anyone have experience with this? > > Many thanks in advance, > Sergei
