Dear All,
I am processing a dataset collected (not by me) with 0.1 degree
oscillations.
The diffraction is quite weak even though there is a clean diffraction
pattern to about 3A.
Either Mosflm or XDS processes the data readily with +/- default settings
but both yield a high overall Rmerge of about 0.23 in the expected symmetry.
Processing in P1 yields an overall Rmerge of ~0.18, but what is
especially disappointing
is that Rmerge is as high as 0.15 at ~5A resolution already.
The question is, how can we process the data so that the merging statistics
becomes more reasonable?
Apparent mosaicity turns out to be ~0.5A. My naive way of thinking is
to try treating each five consecutive frames as a single 0.5 degree frame.
Does anyone have experience with this?
Many thanks in advance,
Sergei
