may be diafiltration devices might work for you. the membranes are kind of expensive but we had used this effectively to reduce the volume of cell culture media where we had secreted proteins in large volumes of culture media.
here is a link http://www.spectrapor.com/lit/hfdial.pdf padayatti On Thu, Sep 3, 2009 at 3:52 AM, Xuan Yang<pattisy...@gmail.com> wrote: > Dear All, > > I am working on protein refolding via dialysis in large volumn > (typically 2~4 litters). It was problematic when I wanted to concentrate the > solution to at least less than 500ml. If you know any device appropriate for > such task, please help me out:) > > Thanks in advance! > > Sincerely, > > Xuan Yang -- Pius S Padayatti Scientist, Polgenix, Inc. 11000 Cedar Ave, Suite 260 Cleveland, OH 44106 Phone: 216-658-4528 Fax: 216-658-4529
