Well, perhaps my inquiry to Anatrace for such a resource (wiki?) will work
out. It was suggested to me that I thus inquire by somebody on this list.
They probably have a lot of data which they have not published anywhere, for
whatever reason. Hope that won't scoop you, or perhaps you would be willing
to comtribute your work so far, and they might pick up some of the data
entry load?
Jacob
*******************************************
Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
Dallos Laboratory
F. Searle 1-240
2240 Campus Drive
Evanston IL 60208
lab: 847.467.4049
cel: 773.608.9185
email: [EMAIL PROTECTED]
*******************************************
----- Original Message -----
From: "Martin.Caffrey" <[EMAIL PROTECTED]>
To: <CCP4BB@JISCMAIL.AC.UK>
Sent: Tuesday, October 23, 2007 2:50 PM
Subject: Re: [ccp4bb] Primary source for detergent properties
I have found Bob Laughlin's book 'The Aqueous Phase Behavior of Surfactants'
to be a useful resource on detergents. It has several relevant phase
diagrams. Heavy on the P. Chem.
Then there is the mother of all info in the area "Critical micelle
concentrations of aqueous surfactant systems" a handbook by Mukerjee and -
you guessed it - Mysels, published in 1971 by the National Bureau of
Standards. No longer in print, it covers the lit from 1926 to the
mid-sixties. A lot of useful info in it (>5,000 records) including effect
of salt, pH and other additives on CMC values.
We have converted the contents of the M&M handbook into a searchable
relational database called the Critical Micelle Concentration Database
(CMCD). The intent was to update it with the latest info on the more
commonly used detergents and to post it on the web. However, this is a lot
of work and requires funding. Alas funding for databases is virtually
impossible to get. We will labor away at it in our 'spare time' and make
what we have available for general use as soon as it is 'presentable'.
Don't hold breath.
Martin Caffrey
University of Limerick
-----Original Message-----
From: CCP4 bulletin board [mailto:[EMAIL PROTECTED] Behalf Of
Nadir T. Mrabet
Sent: Tuesday, October 23, 2007 6:17 PM
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] Primary source for detergent properties
Hi,
The only published compendium on detergents still available (to my
knowledge) is http://www.merckbiosciences.co.uk/docs/docs/LIT/CB0068_M.pdf.
No phase diagrams though.
Regards,
Pr. Nadir T. Mrabet
Cellular & Molecular Biochemistry
INSERM U-724
UHP - Nancy 1, School of Medicine
Avenue de la Foret de Haye, BP 184
54505 Vandoeuvre-les-Nancy Cedex
France
Phone: +33 (0)3.83.68.32.73
Fax: +33 (0)3.83.68.32.79
E-mail: [EMAIL PROTECTED]
Cell.: +33 (0)6.11.35.69.09
R.M. Garavito wrote:
Jacob,
Actually, there is no real definitive compendium of detergents and
their properties (solubility, CMC, aggregation number, etc.). Because
of their importance to industry, commercial compendia, as Anatrace's
catalog, are often the most complete. However, most commercial
compendia are not focused on the detergents we are interested in; they
want to make dishes cleaner while protecting your hands (i.e., SDS is
good). One of the best sources for detergent information of all sorts
is Surfactants and Interfacial Phenomena by M. J. Rosen, but is is
dated and out of print, I believe.
Academic sources are few and often have circular citations. I can
name several cases in the more popular reviews that cannot be traced
back to a original reference. All the real biochemists and chemists
who really brought detergents into biochemistry are retired (e.g., the
Reynolds) or moved on to other things (e.g., Helenius). Lastly, even
when academics measure the properties of a detergent, the work is not
generally published, aside from being buried deeply in a thesis or is
so specific to certain conditions that the information may not be very
useful.
One alternative is to enlist Anatrace and its parent USB, for example,
to set up a Wiki for depositing detergent information and notes.
Thus, anyone who has primary data on detergents could place it there
with relevant experimental details. In the spirit of full disclosure,
I still consult with Anatrace and have provided them with some of my
group's primary data on detergents.
Best regards,
Michael
/****************************************************************/
/R. Michael Garavito, Ph.D./
/Professor of Biochemistry & Molecular Biology/
/513 Biochemistry Bldg. /
/Michigan State University /
/East Lansing, MI 48824-1319/
/Office:// //(517) 355-9724 Lab: (517) 353-9125/
/FAX: (517) 353-9334 Email: [EMAIL PROTECTED]
<mailto:[EMAIL PROTECTED]>/
/****************************************************************/
On Oct 22, 2007, at 5:48 PM, Jacob Keller wrote:
Dear CCP4BB,
Although this is not exactly CCP4-related, I thought somebody here
might know whether there is somewhere a definitive list or tabulation
of detergent properties which are not simply copied out of catalogs,
but have been traceably experimentally determined. In particular, it
would be great to have phase diagrams for common detergents with
detergent concentration versus pH, salt concentration, temperature,
etc. Would this not be incredibly helpful for the scientific
community? And yet, this is not so easy to find....
Jacob
*******************************************
Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
Dallos Laboratory
F. Searle 1-240
2240 Campus Drive
Evanston IL 60208
lab: 847.467.4049
cel: 773.608.9185
email: [EMAIL PROTECTED] <mailto:[EMAIL PROTECTED]>
*******************************************
