On Feb 22, 2007, at 2:35 PM, Nat Echols wrote:

I take it you're only interested in well-characterized and well- known proteins?

Actually no -- well-characterized is good, but well-known is unnecessary.

I have a receiver domain that expresses at >100mg/L and forms crystals right out of most screens that diffract to atomic/ subatomic resolution, but it's still being functionally characterized and the system it's a part of is of limited interest outside of a specific field of microbiology. Experimentally, though, I can't imagine an easier protein to work with.

On Thu, 22 Feb 2007, Douglas L. Theobald wrote:

Hi all,

I'd like to pick the collective brain of crystallographers on this list -- what are some of the most easily crystallizable proteins? I'm especially interested in those that over-express and diffract well, and in ones that might be less well-known than, say, lysozyme (but nearly as nice).

Douglas



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Douglas L. Theobald
Department of Biochemistry
Brandeis University
Waltham, MA  02454-9110

[EMAIL PROTECTED]

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