Does anyone know where I can download a pre-built Coot that will work on OS X
Monterey (12.2) on an iMac with an Intel i7 ?
The packages I can find all fail at the File finder which comes up blank. X11
latest is installed.
Laurence
-
ot Hodgkin
On 17 May 2021, at 17:13, Paul Emsley
mailto:pems...@mrc-lmb.cam.ac.uk>> wrote:
On 17/05/2021 17:08, Laurence Pearl wrote:
Can anyone tell me where to find a model dictionary entry for COOT and/or
phenix for the
Can anyone tell me where to find a model dictionary entry for COOT and/or
phenix for the 7meG-pp residue that forms the 5’ cap on a messenger RNA ? I
need to be able to bond it to the 5’-end of an RNA model and bond it to the
existing 5’-phosphate of the first ribonucleotide.
Thanks,
Laurence
Very sad to hear of the untimely death of Prof. Mavis Agbandje-McKenna who I
had the honour and pleasure of working alongside in Stephen Neidle’s lab at The
Institute of Cancer Research in the late 1980s - there is an obituary from
University of Florida here :
https://m.ufhealth.org/news/2021/w
Can anyone point me at a good server/program for generating polypeptide main
chain from Calpha coordinates ? Sadly the EMBL-EBI MaxSprout server seems to
have been retired.
Laurence H. Pearl PhD FRS FMedSci
Professor of Structural Biology
Gen
A Post-doctoral position funded by Cancer Research UK is available from 1st
October 2019 in the laboratory of Prof. Laurence Pearl FRS and Dr. Antony
Oliver, in the Genome Damage and Stability Centre at the University of Sussex,
to study the structure and mechanism of multi-protein complexes
Post-Doctoral Research Fellow : Structural Biology of DNA Single-strand Break
Repair
(Ref 1739)
A Post-doctoral position funded by Cancer Research UK is available from 1st
October 2019 in the laboratory of Prof. Laurence Pearl FRS and Dr. Antony
Oliver in the Genome Damage and Stability
Just a reminder that the deadline for applying for a Structural Biology Team
Leader post at The Institute of Cancer Research is this Friday 19th July.
https://icr.tal.net/vx/mobile-0/appcentre-ext/brand-0/candidate/so/pm/1/pl/1/opp/768-Team-Leaders-in-Structural-Biology/en-GB
--
gramme for the next 5 years)
For informal enquiries, please contact the Head of Division, Professor Laurence
Pearl FRS – laurence.pe...@icr.ac.uk<mailto:laurence.pe...@icr.ac.uk>
The Closing date for Team Leader applications is15th July 2019
Fellowship positions
The ICR is proactively seeking ca
Post-Doctoral Research Fellow: Conformational Dynamics of HSP90-Kinase Complexes
A Wellcome Trust-funded Post-doctoral Research Fellow position is available
from 1st October 2018 in the laboratory of Prof. Laurence Pearl FRS and Dr.
Chris Prodromou, to study the recruitment, activation and
Picture of electron density didn’t come through, but three planar fused rings
sounds like a flavin - is your protein involved in redox reactions and is it
coloured when concentrated ? The only four ring molecules that spring to mind
are steroids, but these wouldn’t be all that flat and you would
2015
Description
The School of Life Sciences is at the forefront of research in the biological
sciences in the UK, coming in the top 10 in the REF 2014.
A Wellcome Trust-funded postdoctoral position is available immediately in the
laboratory of Professor Laurence Pearl FRS
(http
Laurence Pearl FRS
(http://www.sussex.ac.uk/lifesci/pearllab/) in the Genome Damage and Stability
Centre at Sussex University, to study the structural basis for client protein
recruitment and activation by the Hsp90 molecular chaperone system. We are
very well equipped for all aspects of
Also good to remember the contributions of Peter Kollman who also died too
young and would certainly have been a contender in this splendidly well
directed Nobel prize
Laurence H. Pearl PhD FRS FMedSci
Professor of
September 2013
Description
A Wellcome Trust-funded postdoctoral position is available immediately in the
laboratory of Professor Laurence Pearl FRS
<http://www.sussex.ac.uk/lifesci/pearllab/> in the MRC Genome Damage and
Stability Centre at Sussex University, to study the structural basis for
September 2013
Description
A Wellcome Trust-funded postdoctoral position is available immediately in the
laboratory of Professor Laurence Pearl FRS
<http://www.sussex.ac.uk/lifesci/pearllab/> in the MRC Genome Damage and
Stability Centre at Sussex University, to study the structural basis for
September 2013
Description
A Wellcome Trust-funded postdoctoral position is available immediately in the
laboratory of Professor Laurence Pearl FRS
<http://www.sussex.ac.uk/lifesci/pearllab/> in the MRC Genome Damage and
Stability Centre at Sussex University, to study the structural basis for
laboratory of Professor Laurence Pearl FRS to study the structural basis
for assembly and specificity of multi-protein complexes involved in the
recognition and repair of DNA breaks. The internationally renowned Genome
Damage and Stability Centre and the School of Life Sciences is very well
equipped for
2 Postdoctoral Research Fellows in
Structural Biology of Hsp90 complexes (Ref 041)
Genome Damage and Stability Centre
School of Life Sciences
University of Sussex, Brighton, U.K.
Two Wellcome Trust-funded Postdoctoral positions are available immediately in
the laboratory of Professor Laurence
x.shtml
A Postdoctoral position funded by the Wellcome Trust Strategic Drug
Development Initiative is available immediately in the laboratory of
Professor Laurence Pearl FRS, to analyse complexes of novel
small-molecules with the transcriptional regulatory enzyme, tankyrase.
The postholder will be respo
bsite http://www.icr.ac.uk/index.shtml
A Wellcome Trust-funded Postdoctoral position is available immediately
in the laboratory of Professor Laurence Pearl FRS to study the
structural basis for collaboration between the Hsp90 and Hsp70
molecular chaperone systems in regulation and activation of ‘client’
ry of Professor Laurence Pearl FRS in the Section of
Structural Biology, to study the structural basis for specificity and
assembly of proteins and complexes involved in recognition, signalling
and repair of DNA damage. The Section is exceptionally well equipped
for all aspects of modern struc
Postdoctoral Training Fellow - Structural Biology of Hsp90 Complexes
Section of Structural Biology, ICR
Chester Beatty Laboratories
Chelsea, London, UK
A Wellcome Trust-funded Postdoctoral position is available from 1st
October 2009 in the laboratory of Professor Laurence Pearl FRS, in the
ed on previous post-doctoral experience) and the posts are
offered initially on a fixed term contract of up to 3 years.
Informal enquiries are welcome and can be made to Prof. Laurence Pearl ([EMAIL
PROTECTED]). Please note * this address is for enquiries only and CVs must be
submitted in line wit
contains explicit xyzlim boundaries and "notrim"
keyword.
On Tue, 18 Mar 2008, Laurence Pearl wrote:
I'm trying to generate a mask around a molecule using NCSMASK under
the CCP4i interface, for ultimate use in NCS averaging and density
modification in dm. Being a little old-fashio
I'm trying to generate a mask around a molecule using NCSMASK under the
CCP4i interface, for ultimate use in NCS averaging and density
modification in dm. Being a little old-fashioned I wanted to check that
it covered the required molecule. However when displayed in COOT, there
seem to be arbit
The project is a collaboration between the teams led by Dr. Sibylle Mittnacht
(Cancer Research UK Programme on tumour cell signalling networks) and Prof.
Laurence Pearl (Structural Biology) at the Chester Beatty Laboratories. Between
them these teams share an extensive range of state of the art equip
Postdoctoral Training Fellow - Structural Biology of DNA Repair
Cancer Research UK DNA Repair Enzyme Group
Section of Structural Biology, The Institute of Cancer Research
Chester Beatty Laboratories, Chelsea, London
The Institute of Cancer Research is one of the world's leading
cancer resear
Postdoctoral Training Fellow
Structural Biology of Hsp90 – Client Protein Complexes
Section of Structural Biology
The Institute of Cancer Research
Chester Beatty Laboratories
Chelsea, London
The Institute of Cancer Research is one of the world's leading cancer
research
organisations and is i
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