Postdoctoral Research Fellow in Structural Biology of Hsp90 complexes (Fixed term) Ref 143
School of Life Sciences - Genome Damage and Stability Centre Fixed term for 3 years, full time. Salary range: starting at £31,342 and rising to £37,394 per annum. Closing date for applications: 31 May 2015 Description The School of Life Sciences is at the forefront of research in the biological sciences in the UK, coming in the top 10 in the REF 2014. A Wellcome Trust-funded postdoctoral position is available immediately in the laboratory of Professor Laurence Pearl FRS (http://www.sussex.ac.uk/lifesci/pearllab/) in the MRC Genome Damage and Stability Centre at Sussex University, to study the structural basis for client protein recruitment and activation by the Hsp90 molecular chaperone system. We are very well equipped for all aspects of modern structural biology, with state-of-the-art laboratories for molecular biology, recombinant expression in bacterial and eukaryotic systems, biochemistry, biophysics and X-ray crystallography. Excellent synchrotron access (~2 days/month) is available through rolling beam allocation programmes at Diamond and ESRF. Applicants must have a PhD, and experience in recombinant expression and protein purification. Experience of crystallisation and X-ray crystallography and/or single particle electron microscopy would be an advantage. Information on our previous work in this field can be found at by searching PubMed (pearl [au] and hsp90). The postholder will be responsible for expression, purification, crystallization and structural analysis of protein complexes involving Hsp90, co-chaperones and client proteins that depend on Hsp90 for their biological function. Informal enquiries can be made to Professor Pearl laurence.pe...@sussex.ac.uk<mailto:laurence.pe...@sussex.ac.uk>. The School is committed to equality and valuing diversity, and currently holds an Athena SWAN Bronze Award. Applications are particularly welcomed from women and black and minority ethnic candidates, who are under-represented in academic posts in science and engineering at Sussex. The School of Life Sciences welcomes applications to academic posts from candidates who wish to work part-time or as job-sharers. The University offers various schemes to provide real benefits to parents, these can be found athttp://www.sussex.ac.uk/humanresources/personnel/familyfriendlypolicies Ref 143 Further particulars including person specification [PDF 134.84KB]<http://www.sussex.ac.uk/aboutus/documents/143-fps.pdf> Essential information Terms and conditions Research Faculty Terms and Conditions SUMMARY [DOC 36.00KB]<http://www.sussex.ac.uk/humanresources/documents/research-summ> Application Application form - academic post [DOC 301.50KB]<http://www.sussex.ac.uk/humanresources/documents/acadnw.doc> Please send completed application form by email to: lifescirecruitm...@sussex.ac.uk<mailto:lifescirecruitm...@sussex.ac.uk> When emailing your application please use the following format in the 'subject' line: (post reference number / post title / your name). If you are applying for more than one post advertised by the University, please send a separate email and application form for each post. Please attach your completed application form and any other documents directly to the email rather than using a web-based upload / weblink service (e.g. SkyDrive) otherwise we may not receive your application due to incompatibility with our email software. Or post to: Human Resources Division, Sussex House, University of Sussex, Falmer, Brighton, BN1 9RH. Applications should be received by midnight on the closing date. -------------------------------------------------------------------------------- Laurence H. Pearl PhD FRS FMedSci Professor of Structural Biology and Head of School of Life Sciences University of Sussex, Brighton, BN1 9RH, UK Phone +44-(0)1273 876 544: PA +44-(0)1273 872 699 -------------------------------------------------------------------------------- "Live Modestly and do Serious Things .. " - Dorothy Crowfoot Hodgkin --------------------------------------------------------------------------------
