Re: [ccp4bb] Reg: water pentagon at dimer interface

2019-09-27 Thread Arun Malhotra
The structure of the ice binding protein Maxi from Peter Davies lab (Sun et al. 2014, Science 343, 795-798) had a whole network of pentagonal waters that were critical in holding its unusual structure (waters in the core) together. -- Arun Malhotra Associate Professor of Biochemistry

Re: [ccp4bb] nature cb3 response

2007-08-17 Thread Arun Malhotra
, but this is all retrospective - the time that we really need such analysis is during the review phase of a paper/structure. Arun Malhotra [EMAIL PROTECTED] wrote: Hi Arun, I think you have a higher opinion of journal editors than many of us? Unless you run the same refinement software e

Re: [ccp4bb] nature cb3 response

2007-08-17 Thread Arun Malhotra
anonymous reviewer. The archiving/submission of raw data are important, but it is difficult to see how even competent reviewers can be convinced to do detailed analysis - even for something as easy to check as gels, I have never gone beyond just zooming/squinting when reviewing papers. Aru

Re: [ccp4bb] nature cb3 response

2007-08-17 Thread Arun Malhotra
s reviewer. The archiving/submission of raw data are important, but it is difficult to see how even competent reviewers can be convinced to do detailed analysis - even for something as easy to check as gels, I have never gone beyond just zooming/squinting when reviewing papers. Aru