The structure of the ice binding protein Maxi from Peter Davies lab (Sun et al. 2014, Science 343, 795-798) had a whole network of pentagonal waters that were critical in holding its unusual structure (waters in the core) together.
------ Arun Malhotra Associate Professor of Biochemistry & Molecular Biology Director, Master's in Biomedical Sciences (MiBS) University of Miami Miller School of Medicine Phone: (305) 243-2826 PO Box 016129 Lab: (305) 243-2890 Miami, FL 33101 E-Mail: amalho...@miami.edu <mailto:amalho...@miami.edu> > On Sep 27, 2019, at 7:33 AM, Vijaykumar Pillalamarri > <vijaypkuma...@gmail.com> wrote: > > Dear Community, > > I solved the structure of a protein from vibrio. There are two molecules in > the asymmetric unit of this protein. At the dimer interface, the C-termini of > both the chains interact with each other with the help of five water > molecules that form a pentagon. I have attached an image showing both the > chains and stereo image of dimer interface in the inset. I was wondering if > there is any significance to this or if there is any relevant literature that > explains this behavior. > > Thank you > Vijaykumar Pillalamarri > C/O: Dr. Anthony Addlagatta > Principal Scientist > CSIR-IICT, Tarnaka > Hyderabad, India-500007 > Mobile: +918886922975 > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 > <https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1><Figure1.jpg> ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
