[Freesurfer] Qdec Outputs - Looking For Statistical Maps To Overlay In SurfStat

2009-03-05 Thread Jennifer Bramen

Dear Freesurfer List

I am trying to use SurfStat to create figures based on my qdec  
results. However, I cannot figure out what outputs form qdec are what,  
or what their iunits are. I cannot find a description of qdec's  
outputs on the Freesurfer Wiki.


1) I want to find the statistic overlay for my contrast of interest.  
Qdec creates a folder for each possible test I could make based on the  
design. For exasmple, I would like to overlay the results from the  
folder lh-Avg-thickness-TESSF-Cor.  I think I want to use the  
gamma.mgh file  as my overlay. Is that the true? I have some questions  
about the units of the gamma.mgh files though. When I use SurfStat, it  
automatically scales this at -0.2 - 0.2. I assumed this was the Anti- 
Long P scale used by qdec, so I tried to rescale my display to match  
the colorscale I use to display results in qdec. However, when I tried  
to change the scale to -3 - > 3, I get nothing. In qdec, I do see  
effects using this exact scale(  min 1.3, max 3, min -1.3, max -3). So  
This suggests to me that the gamma.mgh is not in the same units (not  
anti-log(-p)). What are the units?



2) I was told that qdec saves a mean thickness file. I was also told  
it was one of the gamma.mgh files. Qdec creates a folder for each  
hemisphere called, for example, lh-Avg-Intercept-thickness. I assumed  
this was the correct overlay, but it looked to be demeaned as it had  
both negative a positive values. Is it demeaned? Is there a file that  
qdec saves that is just thickness? Or is there a way to manipulate the  
files so that they are not demeaned?


Thank you for your assistance


Best regards,

Jennifer Bramen, Ph.D.
Assistant Research Neuroscientist
David Geffen School of Medicine at UCLA
Developmental Cognitive Neuroimaging 635 Charles Young Drive South
Los Angeles, CA 90095-7332
Phone: (310)267-5116
Fax:  (310)206-5518
Email: jbra...@mednet.ucla.edu
Campus Mail Code 176919

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[Freesurfer] Cannot Configure Segmentation Brush WHen Editing Subcortical Parcellations

2010-02-08 Thread Jennifer Bramen

Dear Freesurfer Support

Cut-and-paste the following info into your FreeSurfer problem report:
-

FREESURFER_HOME: /Applications/freesurfer

Build stamp: freesurfer-Darwin-leopard-i686-stable-pub-v4.5.0

Kernel info: Darwin 9.8.0 i386

-
Please include the following additional information in your report:

  1) subject name
6002
  2) the entire command-line executed
tkmedit 6002 brainmask.mgz lh.white -aux T1.mgz -aux-surface rh.white - 
segmentation aseg.mgz $FREESURFER_HOME/FreeSurferColorLUT.txt &



  3) the error message generated
n/a

I am trying to edit the subcortical parcellations. I found the wiki  
instructions, and have followed (I think) to a t.   I am unable to  
effect the Segmentation Brush label by using the Configure  
Segmentation Brush menu. But regardless of my selection, my drawing is  
labeled "out of bounds".


I have updated to the most recent version of Freesurfer. I also  
attempted to use an older version, in case it was a recent bug,  
incompatible with recon-all done in an older version, etc. However, no  
version changes have helped. Can someone tell me what I am missing?


FYI - When I select a label type, I have tried both having the  
"Segmenmtation Brush Info" window open, with my slection highlighted,  
and highlighting and closing the window. I am hoping I am simply  
missing a step though obvious to the wiki creator.




Here is the link to the "Editing" instructions I have been following:

http://surfer.nmr.mgh.harvard.edu/fswiki/TkMeditGuide/TkMeditWorkingWithData/TkMeditSegmentations


  4) optionally include the subject's /script/recon-all.log

(n/a)


Thanks for your assistance.




Best regards,


Jennifer Bramen, Ph.D.
Assistant Research Neuroscientist
UCLA Center for Cognitive Neuroscience
Developmental Cognitive Neuroimaging
Suite 17-369 740 Westwood Plaza Los Angeles, CA 90095
Phone: (310)525-0865
Fax: (310)206-5518 Email: jbra...@mednet.ucla.edu

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[Freesurfer] Editing Parcellations

2010-02-09 Thread Jennifer Bramen
Dear Freesurfer List

I am trying to edit the parcellations using tkmedit, but I am unable  
to effect the Segmentation Brush label using the Configure  
Segmentation Brush window. Regardless of my selection, my drawing is  
labeled "out of bounds".  I don;t see an apply button or anything like  
that, so I assumed simply highlighting the tissue class in the  
Configuration window would change the brush to my selected label. Is  
there some step I may be moissing when trying to make a selection? I  
am using the most up to date version of Freesurfer, and have also  
tried reverting to older versions, all with no success.

Thanks for you your assistance.


Best regards,

Jennifer Bramen, Ph.D.
Assistant Research Neuroscientist
David Geffen School of Medicine at UCLA
Developmental Cognitive Neuroimaging
635 Charles Young Drive South
Los Angeles, CA 90095-7332
Phone: (310)525-0865
Fax: (310)206-5518
Email: jbra...@mednet.ucla.edu
Campus Mail Code 176919

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[Freesurfer] Cannot execute any freesurfer GUI- Error of failed request:

2008-04-25 Thread Jennifer Bramen

FREESURFER_HOME: /Applications/freesurfer

Build stamp: freesurfer-Darwin-leopard-stable-pub-v4.0.3

Kernel info: Darwin 9.0.0 i386
___

I recently updated to the newest release of freesurfer because for  
some reason I was unable to run qdec with 4.0.2. Though it appears  
that everything is setup exactly as it was before, I cannot execute  
any of the GUI (tkmedit, tksurfer, or qdec)


I tried using the tutorial dataset to debug this. Below is an example  
command:



tkmedit good_output brainmask.mgz lh.white -aux T1.mgz -aux-surface  
rh.white -segmentation aseg.mgz $FREESURFER_HOME/FreeSurferColorLUT.txt


Regardless of what I try to run, I get the following error:


Couldn't create output file .xdebug_tkmeditX Error of failed request:   
BadRequest (invalid request code or no such operation)

 Major opcode of failed request:  128 (Apple-DRI)
 Minor opcode of failed request:  1 ()
 Serial number of failed request:  17
 Current serial number in output stream:  17


I already looked in the archives. I do have the most up to date  
version of X11. I am running this on my local machine, not via ssh, so  
this is not a display problem. All of my necessary variables are set  
(SUBJECTS_DIR, FREESURFER_HOME) and I have sourced $FREESURFER_HOME/ 
SetUpFreeSurfer.csh.


Thnaks you in advance for your help.

Jennifer Bramen

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[Freesurfer] White Matter Regional Volumes

2008-04-25 Thread Jennifer Bramen

Hi Freesurfer Users,

This may be a newbie question. I am trying to evaluate regional  
volumes. I have been able to tabulate the gray matter volumes, but  
cannot figure out how to tabulate all the white matter volumes. I see  
that in individual folders, there is a file called wmparc.stats. Do  
any of the tools query this file, or will I need to pull the data  
manually? Inside this file, I see some of the regions listed as wm-?h- 
. Next to these are sometimes a lot of zeros and sometimes  
a bunch of values. I am wondering why so many of these do not have  
values associated with them. I am also wondering why only some of the  
regions listed in this file are labeled wm, when the file suggests it  
contains white matter stats...


If there is somewhere on the site that explains white matter  
volumetric analyses, could someone please send me the link?


Thank you

Jennifer Bramen

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Re: [Freesurfer] White Matter Regional Volumes

2008-04-29 Thread Jennifer Bramen
I posted the below question regarding white matter volumes to the list  
last Friday. I think it fell through the cracks because I sent it out  
in the late afternoon, and was hoping someone could help me understand  
1) the outputs of indicvidual wmparc.stats files and 2) how to  
tabulate these data like we can with gray matter volumes. Thanks again.


Jen


Hi Freesurfer Users,

This may be a newbie question. I am trying to evaluate regional  
volumes. I have been able to tabulate the gray matter volumes, but  
cannot figure out how to tabulate all the white matter volumes. I  
see that in individual folders, there is a file called wmparc.stats.  
Do any of the tools query this file, or will I need to pull the data  
manually? Inside this file, I see some of the regions listed as wm-? 
h-. Next to these are sometimes a lot of zeros and  
sometimes a bunch of values. I am wondering why so many of these do  
not have values associated with them. I am also wondering why only  
some of the regions listed in this file are labeled wm, when the  
file suggests it contains white matter stats...


If there is somewhere on the site that explains white matter  
volumetric analyses, could someone please send me the link?


Thank you

Jennifer Bramen

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IMPORTANT WARNING:  This email (and any attachments) is only  
intended for the use of the person or entity to which it is  
addressed, and may contain information that is privileged and  
confidential.  You, the recipient, are obligated to maintain it in a  
safe, secure and confidential manner.  Unauthorized redisclosure or  
failure to maintain confidentiality may subject you to federal and  
state penalties. If you are not the intended recipient, please  
immediately notify us by return email, and delete this message from  
your computer.

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[Freesurfer] PETSurfer: error: MatrixReadTxT: could not scan value [1][1]

2022-01-31 Thread Jennifer Bramen
External Email - Use Caution

Hello FreeSurfer Developers,

I'm attempting to analyze amyloid PET data using  PETSurfer. I am trying to do 
kinetic modeling and I am on the MRTM1 step. I have tried this two ways (one 
using the wiki instructions and the other using the tutorial ROI-based approach)

mri_glmfit --y $PET_DIR/PREV_019/gtmpvc.output/km.hb.tac.nii.gz --mrtm1 
$PET_DIR/PREV_019/gtmpvc.output/km.ref.tac.dat $PET_DIR/time.dat --o mrtm1 
--no-est-fwhm --nii.gz; done


 mri_glmfit --y $PET_DIR/PREV_019/gtmpvc.output/gtm.nii.gz --mrtm1 
$PET_DIR/PREV_019/gtmpvc.output/km.ref.tac.dat $PET_DIR/time.dat --o 
$PET_DIR/PREV_019/mrtm1.roi --nii.gz;done

Both times I get this error:

error: MatrixReadTxT: could not scan value [1][1]

I have opened all of the .dat files using my text editor (nano) and they seem 
ok. I have tried this in other subjects and I get the same error.

I searched the list and I cannot find any discussion regarding this error using 
mri_glmfit and PET data.  Anything you can do to help me troubleshoot this 
error would be greatly appreciated!!! Attached is my time.dat file (I think 
this is the most likely culprit).




Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center





time.dat
Description: time.dat
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Re: [Freesurfer] PETSurfer: error: MatrixReadTxT: could not scan value [1][1]

2022-02-07 Thread Jennifer Bramen
External Email - Use Caution

Hi Doug

I think my first question should be “do I need to do KM?”. This is an amyloid 
scan and I want to estimate intensity within regions of interest.  Do I need KM 
to estimate mean intensity?

This is what I know about the timing of the 4 amyloid PET volumes:

5 min (300 sec) – Amyloid Brain

  *   (5 minx 4 beds)
  *   40 min uptake
  *   10 mCi IV injection

Can I just create a mean volume from this image or some other simple metric 
instead of KM?

Thanks for your help.

Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069


From:  on behalf of "Douglas N. Greve" 

Reply-To: Freesurfer support list 
Date: Friday, February 4, 2022 at 5:09 AM
To: "freesurfer@nmr.mgh.harvard.edu" 
Subject: Re: [Freesurfer] PETSurfer: error: MatrixReadTxT: could not scan value 
[1][1]

Can you send all the terminal output?  Also, you only have 4 time points in 
time.dat. Is this accurate? It's going to be hard to do KM with 4 time points.
On 1/31/2022 5:00 PM, Jennifer Bramen wrote:

External Email - Use Caution
Hello FreeSurfer Developers,

I'm attempting to analyze amyloid PET data using  PETSurfer. I am trying to do 
kinetic modeling and I am on the MRTM1 step. I have tried this two ways (one 
using the wiki instructions and the other using the tutorial ROI-based approach)

mri_glmfit --y $PET_DIR/PREV_019/gtmpvc.output/km.hb.tac.nii.gz --mrtm1 
$PET_DIR/PREV_019/gtmpvc.output/km.ref.tac.dat $PET_DIR/time.dat --o mrtm1 
--no-est-fwhm --nii.gz; done


 mri_glmfit --y $PET_DIR/PREV_019/gtmpvc.output/gtm.nii.gz --mrtm1 
$PET_DIR/PREV_019/gtmpvc.output/km.ref.tac.dat $PET_DIR/time.dat --o 
$PET_DIR/PREV_019/mrtm1.roi --nii.gz;done

Both times I get this error:

error: MatrixReadTxT: could not scan value [1][1]

I have opened all of the .dat files using my text editor (nano) and they seem 
ok. I have tried this in other subjects and I get the same error.

I searched the list and I cannot find any discussion regarding this error using 
mri_glmfit and PET data.  Anything you can do to help me troubleshoot this 
error would be greatly appreciated!!! Attached is my time.dat file (I think 
this is the most likely culprit).




Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center







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Re: [Freesurfer] PETSurfer: error: MatrixReadTxT: could not scan value [1][1]

2022-02-10 Thread Jennifer Bramen
External Email - Use Caution

Hi Doug

I think I figured out my answer.  ADNI does 4 volume Amyloid PET analyses by 
averaging the 4 volumes together. I do not need to do kinetic modeling. I hope 
this helps someone else in the same situation in the future.

Thanks!
Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404



From:  on behalf of Jennifer Bramen 

Reply-To: Freesurfer support list 
Date: Monday, February 7, 2022 at 9:50 AM
To: Freesurfer support list 
Subject: Re: [Freesurfer] PETSurfer: error: MatrixReadTxT: could not scan value 
[1][1]


External Email - Use Caution
Hi Doug

I think my first question should be “do I need to do KM?”. This is an amyloid 
scan and I want to estimate intensity within regions of interest.  Do I need KM 
to estimate mean intensity?

This is what I know about the timing of the 4 amyloid PET volumes:

5 min (300 sec) – Amyloid Brain

  *   (5 minx 4 beds)
  *   40 min uptake
  *   10 mCi IV injection

Can I just create a mean volume from this image or some other simple metric 
instead of KM?

Thanks for your help.

Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404


From:  on behalf of "Douglas N. Greve" 

Reply-To: Freesurfer support list 
Date: Friday, February 4, 2022 at 5:09 AM
To: "freesurfer@nmr.mgh.harvard.edu" 
Subject: Re: [Freesurfer] PETSurfer: error: MatrixReadTxT: could not scan value 
[1][1]

Can you send all the terminal output?  Also, you only have 4 time points in 
time.dat. Is this accurate? It's going to be hard to do KM with 4 time points.
On 1/31/2022 5:00 PM, Jennifer Bramen wrote:

External Email - Use Caution
Hello FreeSurfer Developers,

I'm attempting to analyze amyloid PET data using  PETSurfer. I am trying to do 
kinetic modeling and I am on the MRTM1 step. I have tried this two ways (one 
using the wiki instructions and the other using the tutorial ROI-based approach)

mri_glmfit --y $PET_DIR/PREV_019/gtmpvc.output/km.hb.tac.nii.gz --mrtm1 
$PET_DIR/PREV_019/gtmpvc.output/km.ref.tac.dat $PET_DIR/time.dat --o mrtm1 
--no-est-fwhm --nii.gz; done


 mri_glmfit --y $PET_DIR/PREV_019/gtmpvc.output/gtm.nii.gz --mrtm1 
$PET_DIR/PREV_019/gtmpvc.output/km.ref.tac.dat $PET_DIR/time.dat --o 
$PET_DIR/PREV_019/mrtm1.roi --nii.gz;done

Both times I get this error:

error: MatrixReadTxT: could not scan value [1][1]

I have opened all of the .dat files using my text editor (nano) and they seem 
ok. I have tried this in other subjects and I get the same error.

I searched the list and I cannot find any discussion regarding this error using 
mri_glmfit and PET data.  Anything you can do to help me troubleshoot this 
error would be greatly appreciated!!! Attached is my time.dat file (I think 
this is the most likely culprit).




Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center









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[Freesurfer] PetSurfer: subcortical volume-based analysis

2022-02-14 Thread Jennifer Bramen
External Email - Use Caution

Dear Freesurfer Developers

I am doing an ROI--based amyloid PET scan analysis. I have completed all of the 
steps from the PetSurfer wiki. I now have the preprocessed, averaged, 
resampled, smoothed PET data in MNI305 space which is constrained to the 
subcortical gray matter mask.

How do I extract mean intensity within all of the subcortical ROI?

Thank you!

Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069


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[Freesurfer] PetSurfer: CORTICAL volume-based analysis

2022-02-14 Thread Jennifer Bramen
External Email - Use Caution

Dear Freesurfer Developers

I am doing an ROI--based amyloid PET scan analysis. I am following the steps 
from the PetSurfer wiki. I see instructions for how to do a cortical 
surface-based group analysis. I also see how to do a subcortical ROI-based 
analysis. However, I cannot find detailed instructions for performing a 
cortical ROI-based analysis.



This is how I think I should adapt the instructions from your subcortical 
ROI-based analysis instructions for cortical gray matter:

mri_vol2vol --mov $PET_DIR/$ID/gtmpvc.output/mgx.gm.nii.gz --reg 
$PET_DIR/$ID/gtmpvc.output/aux/bbpet2anat.lta --tal --talres 2 --o 
$PET_DIR/$ID/gtmpvc.output/gm.mni305.2mm.sm00.nii.gz

mri_fwhm --smooth-only --i $PET_DIR/$ID/gtmpvc.output/gm.mni305.2mm.sm00.nii.gz 
--fwhm 5 --o $PET_DIR/$ID/gtmpvc.output/gm.mni305.2mm.sm05.nii.gz --mask 
$FREESURFER_HOME/subjects/fsaverage/mri.2mm/brainmask.mgz


Can someone confirm or correct these commands? I am especially concerned that I 
have selected the wrong mask.


Thanks you!
Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center



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Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

2022-02-21 Thread Jennifer Bramen
External Email - Use Caution

I am trying to extract mean intensity in my PET data for every ROI. Doug said 
to run mri_segstats passing the PET with --i and using --seg to spec the 
segmentation. I would like to confirm that I am using this properly.

mri_segstats --i $PET_DIR/$ID/gtmpvc.output/mgx.gm_average.T1.nii.gz --seg 
$SUBJECTS_DIR/$ID/mri/aparc+aseg.mgz --annot lh --slabel lh --sum 
$PET_DIR/$ID/gtmpvc.output/lh.PET_aparc.aseg

where $PET_DIR/$ID/gtmpvc.output/mgx.gm_average.T1.nii.gz is the PET data 
registered and resampled into the individual’s T1-weighrd MRI space.



Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069


From:  on behalf of "Douglas N. Greve" 

Reply-To: Freesurfer support list 
Date: Wednesday, February 16, 2022 at 7:30 AM
To: "freesurfer@nmr.mgh.harvard.edu" 
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

If you want to do an ROI analysis using FS-based ROIs, you should do that at 
the individual level. Resample the PET to the anatoimical space, then run 
mri_segstats passing the PET with --i and using --seg to spec the segmentation. 
If you really want to do it in MNI305 space, then it is the same thing just 
using the MNI305-based (2mm) segmentation
On 2/14/2022 6:11 PM, Jennifer Bramen wrote:

External Email - Use Caution
Dear Freesurfer Developers

I am doing an ROI--based amyloid PET scan analysis. I have completed all of the 
steps from the PetSurfer wiki. I now have the preprocessed, averaged, 
resampled, smoothed PET data in MNI305 space which is constrained to the 
subcortical gray matter mask.

How do I extract mean intensity within all of the subcortical ROI?

Thank you!

Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069





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Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

2022-02-21 Thread Jennifer Bramen
External Email - Use Caution

Thanks! Yes, I already mapped my PET to anatomical space using mri_vol2vol and 
glmdir/aux/bbpet2anat.lta.

RE: selection of mgx instead of gtm: I am analyzing amyloid PET data and I 
believe it is recommended to extract gray matter localized PET data. Is that 
what I am doing by using the mgx image?

Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069



From:  on behalf of "Douglas N. Greve" 

Reply-To: Freesurfer support list 
Date: Monday, February 21, 2022 at 2:02 PM
To: "freesurfer@nmr.mgh.harvard.edu" 
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

You need to first map your pet to the anatomical space using mri_vol2vol and 
the registration glmdir/aux/bbpet2anat.lta
BTW, why are you computing the ROI anlaysis from the mgx data instead of using 
the output from the gtm? Note that you cannot use the white matter values that 
come from  mgx.
On 2/21/2022 12:57 PM, Jennifer Bramen wrote:

External Email - Use Caution
I am trying to extract mean intensity in my PET data for every ROI. Doug said 
to run mri_segstats passing the PET with --i and using --seg to spec the 
segmentation. I would like to confirm that I am using this properly.

mri_segstats --i $PET_DIR/$ID/gtmpvc.output/mgx.gm_average.T1.nii.gz --seg 
$SUBJECTS_DIR/$ID/mri/aparc+aseg.mgz --annot lh --slabel lh --sum 
$PET_DIR/$ID/gtmpvc.output/lh.PET_aparc.aseg

where $PET_DIR/$ID/gtmpvc.output/mgx.gm_average.T1.nii.gz is the PET data 
registered and resampled into the individual’s T1-weighrd MRI space.



Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069


From: 
<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of "Douglas N. Greve" 
<mailto:dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Wednesday, February 16, 2022 at 7:30 AM
To: "freesurfer@nmr.mgh.harvard.edu"<mailto:freesurfer@nmr.mgh.harvard.edu> 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

If you want to do an ROI analysis using FS-based ROIs, you should do that at 
the individual level. Resample the PET to the anatoimical space, then run 
mri_segstats passing the PET with --i and using --seg to spec the segmentation. 
If you really want to do it in MNI305 space, then it is the same thing just 
using the MNI305-based (2mm) segmentation
On 2/14/2022 6:11 PM, Jennifer Bramen wrote:

External Email - Use Caution
Dear Freesurfer Developers

I am doing an ROI--based amyloid PET scan analysis. I have completed all of the 
steps from the PetSurfer wiki. I now have the preprocessed, averaged, 
resampled, smoothed PET data in MNI305 space which is constrained to the 
subcortical gray matter mask.

How do I extract mean intensity within all of the subcortical ROI?

Thank you!

Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069






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Frees

Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

2022-02-22 Thread Jennifer Bramen
External Email - Use Caution


If I only want to extract intensity from gray matter, do I need to add an 
additional mask?

Thanks!

Jennifer

Get Outlook for 
iOS<https://secure-web.cisco.com/1L8X_xbSuY_t_ihVbCVT-VrYnrnVaUkpY43uE0_YCYKJhAviIYu8oxZ5PPt-xMtue1nKBFFsIIdc4KBLgKFCEwa74gpigVENV1GyuIW9GZY7CdyW1O-DI9kzTj0IqZfoGPgj6xImBezDDXVXDYk72vjK3VGgjUz9iLXe0ZpQBziIaJ_lOjni1eZ5hbGxBsHdweSgAAcH3WrreH39jB3E5W_oCbiM_eemv-N1wxKjATTFgYLmBFmxGUK3F_I7myhQ2giptsjKDwBlg67W0Te63GAUl8h6wI9xpMnF5vpkiBB50ky4Fc1twBGrvBs8O3yh8Jw9cAIYSm4G0yFmFVx77AA/https%3A%2F%2Faka.ms%2Fo0ukef>

From: freesurfer-boun...@nmr.mgh.harvard.edu 
 on behalf of Douglas N. Greve 

Sent: Monday, February 21, 2022 7:13:39 PM
To: freesurfer@nmr.mgh.harvard.edu 
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

The GTM gives you values for each ROI regardless of whether it is GM, WM, or 
CSF. They will probably give you similar answers, but the GTM will be more 
robust.

On 2/21/2022 8:48 PM, Jennifer Bramen wrote:

External Email - Use Caution

Thanks! Yes, I already mapped my PET to anatomical space using mri_vol2vol and 
glmdir/aux/bbpet2anat.lta.



RE: selection of mgx instead of gtm: I am analyzing amyloid PET data and I 
believe it is recommended to extract gray matter localized PET data. Is that 
what I am doing by using the mgx image?



Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069







From: 
<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of "Douglas N. Greve" 
<mailto:dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Monday, February 21, 2022 at 2:02 PM
To: "freesurfer@nmr.mgh.harvard.edu"<mailto:freesurfer@nmr.mgh.harvard.edu> 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis



You need to first map your pet to the anatomical space using mri_vol2vol and 
the registration glmdir/aux/bbpet2anat.lta
BTW, why are you computing the ROI anlaysis from the mgx data instead of using 
the output from the gtm? Note that you cannot use the white matter values that 
come from  mgx.

On 2/21/2022 12:57 PM, Jennifer Bramen wrote:

External Email - Use Caution

I am trying to extract mean intensity in my PET data for every ROI. Doug said 
to run mri_segstats passing the PET with --i and using --seg to spec the 
segmentation. I would like to confirm that I am using this properly.



mri_segstats --i $PET_DIR/$ID/gtmpvc.output/mgx.gm_average.T1.nii.gz --seg 
$SUBJECTS_DIR/$ID/mri/aparc+aseg.mgz --annot lh --slabel lh --sum 
$PET_DIR/$ID/gtmpvc.output/lh.PET_aparc.aseg



where $PET_DIR/$ID/gtmpvc.output/mgx.gm_average.T1.nii.gz is the PET data 
registered and resampled into the individual’s T1-weighrd MRI space.







Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069





From: 
<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of "Douglas N. Greve" 
<mailto:dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Wednesday, February 16, 2022 at 7:30 AM
To: "freesurfer@nmr.mgh.harvard.edu"<mailto:freesurfer@nmr.mgh.harvard.edu> 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis



If you want to do an ROI analysis using FS-based ROIs, you should do that at 
the individual level. Resample the PET to the anatoimical space, then run 
mri_segstats passing the PET with --i and using --seg to spec the segmentation. 
If you really want to do it in MNI305 space, then it is the same thing just 
using the MNI305-based (2mm) segmentation

On 2/14/2022 6:11 PM, Jennifer Bramen wrote:

External Email - Use Caution

Dear Freesurfer Developers



I am doing an ROI--based amyloid PET scan analysis. I have completed all of the 
steps from the PetSurfer wiki. I now have the preprocessed, averaged, 
resampled, smoothed PET data in MNI305 space which is constrained to the 
subcortical gray matter mask.



How do I extract mean intensity within all of the subcortical ROI?



Thank you!



Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Founda

Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

2022-02-24 Thread Jennifer Bramen
External Email - Use Caution


I would like to measure uptake exclusively in gray matter. What would you 
recommend to accomplish this?
In my previous message, I was wondering if adding a gray matter mask would be a 
potential way to restrict the analysis to gray matter. Thanks!

Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069



From:  on behalf of "Douglas N. Greve" 

Reply-To: Freesurfer support list 
Date: Tuesday, February 22, 2022 at 3:00 PM
To: "freesurfer@nmr.mgh.harvard.edu" 
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

I don't understand. What mask?
On 2/22/2022 8:55 AM, Jennifer Bramen wrote:

External Email - Use Caution


If I only want to extract intensity from gray matter, do I need to add an 
additional mask?

Thanks!

Jennifer

Get Outlook for 
iOS<https://secure-web.cisco.com/1L8X_xbSuY_t_ihVbCVT-VrYnrnVaUkpY43uE0_YCYKJhAviIYu8oxZ5PPt-xMtue1nKBFFsIIdc4KBLgKFCEwa74gpigVENV1GyuIW9GZY7CdyW1O-DI9kzTj0IqZfoGPgj6xImBezDDXVXDYk72vjK3VGgjUz9iLXe0ZpQBziIaJ_lOjni1eZ5hbGxBsHdweSgAAcH3WrreH39jB3E5W_oCbiM_eemv-N1wxKjATTFgYLmBFmxGUK3F_I7myhQ2giptsjKDwBlg67W0Te63GAUl8h6wI9xpMnF5vpkiBB50ky4Fc1twBGrvBs8O3yh8Jw9cAIYSm4G0yFmFVx77AA/https%3A%2F%2Faka.ms%2Fo0ukef>

From: 
freesurfer-boun...@nmr.mgh.harvard.edu<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 
<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of Douglas N. Greve 
<mailto:dgr...@mgh.harvard.edu>
Sent: Monday, February 21, 2022 7:13:39 PM
To: freesurfer@nmr.mgh.harvard.edu<mailto:freesurfer@nmr.mgh.harvard.edu> 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

The GTM gives you values for each ROI regardless of whether it is GM, WM, or 
CSF. They will probably give you similar answers, but the GTM will be more 
robust.
On 2/21/2022 8:48 PM, Jennifer Bramen wrote:

External Email - Use Caution

Thanks! Yes, I already mapped my PET to anatomical space using mri_vol2vol and 
glmdir/aux/bbpet2anat.lta.



RE: selection of mgx instead of gtm: I am analyzing amyloid PET data and I 
believe it is recommended to extract gray matter localized PET data. Is that 
what I am doing by using the mgx image?



Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069







From: 
<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of "Douglas N. Greve" 
<mailto:dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Monday, February 21, 2022 at 2:02 PM
To: "freesurfer@nmr.mgh.harvard.edu"<mailto:freesurfer@nmr.mgh.harvard.edu> 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis



You need to first map your pet to the anatomical space using mri_vol2vol and 
the registration glmdir/aux/bbpet2anat.lta
BTW, why are you computing the ROI anlaysis from the mgx data instead of using 
the output from the gtm? Note that you cannot use the white matter values that 
come from  mgx.

On 2/21/2022 12:57 PM, Jennifer Bramen wrote:

External Email - Use Caution

I am trying to extract mean intensity in my PET data for every ROI. Doug said 
to run mri_segstats passing the PET with --i and using --seg to spec the 
segmentation. I would like to confirm that I am using this properly.



mri_segstats --i $PET_DIR/$ID/gtmpvc.output/mgx.gm_average.T1.nii.gz --seg 
$SUBJECTS_DIR/$ID/mri/aparc+aseg.mgz --annot lh --slabel lh --sum 
$PET_DIR/$ID/gtmpvc.output/lh.PET_aparc.aseg



where $PET_DIR/$ID/gtmpvc.output/mgx.gm_average.T1.nii.gz is the PET data 
registered and resampled into the individual’s T1-weighrd MRI space.







Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069





From: 
<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of "Douglas N. Greve" 
<mailto:dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Wednesday, February 16, 2022 at 7:30 AM
To: "freesurfer@nmr.mgh.harvard.edu"<mailto:f

Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

2022-02-25 Thread Jennifer Bramen
External Email - Use Caution

Hi Doug

I want to confirm that the signal any region flagged as cortex is restricted to 
gray matter. If that is the case, then I finally have what I need. Thank you.

Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069


From:  on behalf of "Douglas N. Greve" 

Reply-To: Freesurfer support list 
Date: Friday, February 25, 2022 at 10:25 AM
To: "freesurfer@nmr.mgh.harvard.edu" 
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

Are you doing an ROI analysis or a voxel-wise analysis? If an ROI analysis, 
then use mri_gtmpvc (with or without PVC). This will give you GM, WM, and CSF 
ROIs. Or do you mean you want a single average across all GM?
On 2/24/2022 1:15 PM, Jennifer Bramen wrote:

External Email - Use Caution

I would like to measure uptake exclusively in gray matter. What would you 
recommend to accomplish this?
In my previous message, I was wondering if adding a gray matter mask would be a 
potential way to restrict the analysis to gray matter. Thanks!

Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069



From: 
<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of "Douglas N. Greve" 
<mailto:dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Tuesday, February 22, 2022 at 3:00 PM
To: "freesurfer@nmr.mgh.harvard.edu"<mailto:freesurfer@nmr.mgh.harvard.edu> 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

I don't understand. What mask?
On 2/22/2022 8:55 AM, Jennifer Bramen wrote:

External Email - Use Caution


If I only want to extract intensity from gray matter, do I need to add an 
additional mask?

Thanks!

Jennifer

Get Outlook for 
iOS<https://secure-web.cisco.com/1L8X_xbSuY_t_ihVbCVT-VrYnrnVaUkpY43uE0_YCYKJhAviIYu8oxZ5PPt-xMtue1nKBFFsIIdc4KBLgKFCEwa74gpigVENV1GyuIW9GZY7CdyW1O-DI9kzTj0IqZfoGPgj6xImBezDDXVXDYk72vjK3VGgjUz9iLXe0ZpQBziIaJ_lOjni1eZ5hbGxBsHdweSgAAcH3WrreH39jB3E5W_oCbiM_eemv-N1wxKjATTFgYLmBFmxGUK3F_I7myhQ2giptsjKDwBlg67W0Te63GAUl8h6wI9xpMnF5vpkiBB50ky4Fc1twBGrvBs8O3yh8Jw9cAIYSm4G0yFmFVx77AA/https%3A%2F%2Faka.ms%2Fo0ukef>

From: 
freesurfer-boun...@nmr.mgh.harvard.edu<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 
<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of Douglas N. Greve 
<mailto:dgr...@mgh.harvard.edu>
Sent: Monday, February 21, 2022 7:13:39 PM
To: freesurfer@nmr.mgh.harvard.edu<mailto:freesurfer@nmr.mgh.harvard.edu> 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

The GTM gives you values for each ROI regardless of whether it is GM, WM, or 
CSF. They will probably give you similar answers, but the GTM will be more 
robust.
On 2/21/2022 8:48 PM, Jennifer Bramen wrote:

External Email - Use Caution

Thanks! Yes, I already mapped my PET to anatomical space using mri_vol2vol and 
glmdir/aux/bbpet2anat.lta.



RE: selection of mgx instead of gtm: I am analyzing amyloid PET data and I 
believe it is recommended to extract gray matter localized PET data. Is that 
what I am doing by using the mgx image?



Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069







From: 
<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of "Douglas N. Greve" 
<mailto:dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Monday, February 21, 2022 at 2:02 PM
To: "freesurfer@nmr.mgh.harvard.edu"<mailto:freesurfer@nmr.mgh.harvard.edu> 
<mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis



You need to first map your pet to the anatomical space using mri_vol2vol and 
the registration glmdir/aux/bbpet2anat.lta
BTW, why are you computing the ROI anlaysis from the mgx data instead of using 
the output from the gtm? Note that you cannot use the white matter values that 
come from  mgx.

On 2/21/2022 12:57 PM, Jennifer Bram

[Freesurfer] mri_convert and timeseries data

2011-06-01 Thread Jennifer Bramen

Dear Freesurfer Users

I am trying to use mri_convert to reorient a nifti file. The file is a  
bold sequence, but for some reason, mri_convert is only outputting the  
first volume. I get this error as well:


WARNING: niiRead(): unknown time units 0 in 2010_10_20_21_bold_gp2.nii

Any idea regarding what I am doing wrong? Here is the command I used:

mri_convert --in_orientation SLP --out_orientation LPI   
2010_10_20_21_bold_gp2.nii 2010_10_20_21_bold_gp_RPI2.nii


Any help would be greatly appreciated!

Best regards

Jen


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