External Email - Use Caution        

I am trying to extract mean intensity in my PET data for every ROI. Doug said 
to run mri_segstats passing the PET with --i and using --seg to spec the 
segmentation. I would like to confirm that I am using this properly.

mri_segstats --i $PET_DIR/$ID/gtmpvc.output/mgx.gm_average.T1.nii.gz --seg 
$SUBJECTS_DIR/$ID/mri/aparc+aseg.mgz --annot lh --slabel lh --sum 
$PET_DIR/$ID/gtmpvc.output/lh.PET_aparc.aseg

where $PET_DIR/$ID/gtmpvc.output/mgx.gm_average.T1.nii.gz is the PET data 
registered and resampled into the individual’s T1-weighrd MRI space.



Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069


From: <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of "Douglas N. Greve" 
<dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Date: Wednesday, February 16, 2022 at 7:30 AM
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] PetSurfer: subcortical volume-based analysis

If you want to do an ROI analysis using FS-based ROIs, you should do that at 
the individual level. Resample the PET to the anatoimical space, then run 
mri_segstats passing the PET with --i and using --seg to spec the segmentation. 
If you really want to do it in MNI305 space, then it is the same thing just 
using the MNI305-based (2mm) segmentation
On 2/14/2022 6:11 PM, Jennifer Bramen wrote:

        External Email - Use Caution
Dear Freesurfer Developers

I am doing an ROI--based amyloid PET scan analysis. I have completed all of the 
steps from the PetSurfer wiki. I now have the preprocessed, averaged, 
resampled, smoothed PET data in MNI305 space which is constrained to the 
subcortical gray matter mask.

How do I extract mean intensity within all of the subcortical ROI?

Thank you!

Warm regards,


Jennifer Bramen, PhD
(she/her/hers)
Senior Research Scientist, Neuroimaging
Assistant Professor
Pacific Brain Health Center | Pacific Neuroscience Institute & Foundation | 
Providence Saint John's Health Center
1301 20th St. #150 Santa Monica, CA 90404
Phone: 310-525-0865  | Fax: 310-315-4069





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