Re: [Freesurfer] Hippocampal subfields segmentation - what is the voxel size of the input?

2016-06-09 Thread Iglesias, Eugenio
Hi Fernando,

Unfortunately, FreeSurfer does downsample the T1s to 1mm, and the subfield code 
assumes that the T1 comes from FreeSurfer… For the paper, I hacked the code to 
take advantage of multiple images with higher resolution, but it hasn’t been 
thoroughly tested and it’s not publicly available at this point.
That said, there are different things you can do at this point:
1. Use the T1+T2 as is (disadvantage: T1 will be resampled to 1 mm).
2. Use only the T2.
3. Use only the T1. To do this, you would use the T1 as additional scan on its 
own (i.e., the main and additional scans are the same, but the additional one 
won’t be resampled).
4. There might be a way (hack) of using both scans at full resolution. If you 
change the header of the T1 scan and specify that the voxel size is 1mm, no 
resampling will happen; FreeSurfer will believe that you’re dealing with a 
subject with a very large head. If you do this, you’ll also have to enlarge the 
voxel size of the T2 by a factor 1/0.7. Also, the resulting volumes will have 
to be divided by (1/0.7)^3 in order to correct for the “wrong” voxel size.

I hope this helps!

Cheers,

Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 9 Jun 2016, at 19:23, Fernando Pasquini Santos 
mailto:fernandop...@gmail.com>> wrote:

Dear,

I have a doubt regarding the input T1 image used for the Hippocampal Subfield 
segmentation in Freesurfer 6.0 - 
https://surfer.nmr.mgh.harvard.edu/fswiki/HippocampalSubfields

In this documentation it says that I can use a standard 1mm T1 image or the 
same standard 1mm T1 image with an additional scan. However, I want to use a 
0.7mm T1 image as input, with an additional T2 scan. When I run the program 
with it, the output images (nu.mgz and orig.mgz) are downsampled to 1mm voxel 
size. So, I don't know if this happens just because of the recon-all program or 
if the segmentation is being done in the downsampled T1 image or in the 
original 0.7mm.

By reading the article "A computational atlas of the hippocampal formation 
using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation 
of in vivo MRI" I saw that, in the methods section, the algorithm is used to 
segment 0.6mm T1 images. But is this possible to do in the Freesurfer package? 
Obviously, doing the segmentation directly on 0.7mm data would be better than a 
downsampled version to 1mm...

Thanks,

Fernando Pasquini Santos
PhD student in Dynamic Systems
fernandosan...@pitt.edu
fernando.pasquini.san...@usp.br
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Re: [Freesurfer] Hippocampal subfields segmentation - what is the voxel size of the input?

2016-06-09 Thread Iglesias, Eugenio
Hi Matt,
you can use strategy 3 of my previous email ;-)
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 9 Jun 2016, at 19:31, Matt Glasser mailto:m...@ma-tea.com>> 
wrote:

I would be interested to know how well 0.7mm isotropic resolution data performs 
at hippocampal segmentation.  It would be better if folks could do this then 
needing to acquire specialized anisotropic scans for hippocampal segmentation.

Peace,

Matt.

From: 
mailto:freesurfer-boun...@nmr.mgh.harvard.edu>>
 on behalf of Fernando Pasquini Santos 
mailto:fernandop...@gmail.com>>
Reply-To: Freesurfer support list 
mailto:freesurfer@nmr.mgh.harvard.edu>>
Date: Thursday, June 9, 2016 at 1:23 PM
To: "freesurfer@nmr.mgh.harvard.edu" 
mailto:freesurfer@nmr.mgh.harvard.edu>>
Subject: [Freesurfer] Hippocampal subfields segmentation - what is the voxel 
size of the input?

Dear,

I have a doubt regarding the input T1 image used for the Hippocampal Subfield 
segmentation in Freesurfer 6.0 - 
https://surfer.nmr.mgh.harvard.edu/fswiki/HippocampalSubfields

In this documentation it says that I can use a standard 1mm T1 image or the 
same standard 1mm T1 image with an additional scan. However, I want to use a 
0.7mm T1 image as input, with an additional T2 scan. When I run the program 
with it, the output images (nu.mgz and orig.mgz) are downsampled to 1mm voxel 
size. So, I don't know if this happens just because of the recon-all program or 
if the segmentation is being done in the downsampled T1 image or in the 
original 0.7mm.

By reading the article "A computational atlas of the hippocampal formation 
using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation 
of in vivo MRI" I saw that, in the methods section, the algorithm is used to 
segment 0.6mm T1 images. But is this possible to do in the Freesurfer package? 
Obviously, doing the segmentation directly on 0.7mm data would be better than a 
downsampled version to 1mm...

Thanks,

Fernando Pasquini Santos
PhD student in Dynamic Systems
fernandosan...@pitt.edu
fernando.pasquini.san...@usp.br
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Re: [Freesurfer] Hippocampal subfields segmentation - what is the voxel size of the input?

2016-06-10 Thread Iglesias, Eugenio
Hi Matt,
Bruce actually mentioned this possibility yesterday. Good to hear it doesn’t 
crash when you run it! That said, I need to go through the code, and make sure 
that data are handled the way they are supposed to: the fact that it doesn’t 
crash doesn’t directly imply that it is working properly. Hopefully I’ll find 
time to do this next week…
Cheers,
Eugenio


Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 9 Jun 2016, at 21:51, Hibert, Matthew Louis 
mailto:mhib...@mgh.harvard.edu>> wrote:

Hi Eugenio,
Would it also be possible to use the -hires flag in the initial recon-all 
command to prevent the T1 from being downsampled and maintain the voxel size 
that the T1 was acquired at, and use that resulting recon for the hippocampal 
subfield segmentation?  I've tested this with MEMPRAGE scans acquired at 0.75mm 
isotropic and coronal T2 anisotropic scans acquired at 0.33mm in plane with 1mm 
thick slices, and the results look reasonable.  The "1mm" label files are 
correctly downsampled to 0.75mm instead of 1mm, and the higher resolution label 
files remain at 0.33mm resolution.

Thanks,
Matt

Stufflebeam Lab
Athinoula A. Martinos Center
Massachusetts General Hospital
149 13th Street, Room 1115S
Charlestown, MA 02129

From: 
freesurfer-boun...@nmr.mgh.harvard.edu<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 
[freesurfer-boun...@nmr.mgh.harvard.edu<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>]
 on behalf of Iglesias, Eugenio 
[e.igles...@ucl.ac.uk<mailto:e.igles...@ucl.ac.uk>]
Sent: Thursday, June 09, 2016 2:36 PM
To: Freesurfer support list
Subject: Re: [Freesurfer] Hippocampal subfields segmentation - what is the 
voxel size of the input?

Hi Fernando,

Unfortunately, FreeSurfer does downsample the T1s to 1mm, and the subfield code 
assumes that the T1 comes from FreeSurfer… For the paper, I hacked the code to 
take advantage of multiple images with higher resolution, but it hasn’t been 
thoroughly tested and it’s not publicly available at this point.
That said, there are different things you can do at this point:
1. Use the T1+T2 as is (disadvantage: T1 will be resampled to 1 mm).
2. Use only the T2.
3. Use only the T1. To do this, you would use the T1 as additional scan on its 
own (i.e., the main and additional scans are the same, but the additional one 
won’t be resampled).
4. There might be a way (hack) of using both scans at full resolution. If you 
change the header of the T1 scan and specify that the voxel size is 1mm, no 
resampling will happen; FreeSurfer will believe that you’re dealing with a 
subject with a very large head. If you do this, you’ll also have to enlarge the 
voxel size of the T2 by a factor 1/0.7. Also, the resulting volumes will have 
to be divided by (1/0.7)^3 in order to correct for the “wrong” voxel size.

I hope this helps!

Cheers,

Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 9 Jun 2016, at 19:23, Fernando Pasquini Santos 
mailto:fernandop...@gmail.com>> wrote:

Dear,

I have a doubt regarding the input T1 image used for the Hippocampal Subfield 
segmentation in Freesurfer 6.0 - 
https://surfer.nmr.mgh.harvard.edu/fswiki/HippocampalSubfields

In this documentation it says that I can use a standard 1mm T1 image or the 
same standard 1mm T1 image with an additional scan. However, I want to use a 
0.7mm T1 image as input, with an additional T2 scan. When I run the program 
with it, the output images (nu.mgz and orig.mgz) are downsampled to 1mm voxel 
size. So, I don't know if this happens just because of the recon-all program or 
if the segmentation is being done in the downsampled T1 image or in the 
original 0.7mm.

By reading the article "A computational atlas of the hippocampal formation 
using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation 
of in vivo MRI" I saw that, in the methods section, the algorithm is used to 
segment 0.6mm T1 images. But is this possible to do in the Freesurfer package? 
Obviously, doing the segmentation directly on 0.7mm data would be better than a 
downsampled version to 1mm...

Thanks,

Fernando Pasquini Santos
PhD student in Dynamic Systems
fernandosan...@pitt.edu<mailto:fernandosan...@pitt.edu>
fernando.pasquini.san...@usp.br<mailto:fernando.pasquini.san...@usp.br>
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Re: [Freesurfer] Brainstem Substructures does not work.

2016-06-10 Thread Iglesias, Eugenio
FreeSurfer 6.0 is not available yet, but you can download the development 
version to take advantage of this functionality.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 10 Jun 2016, at 18:10, shi yao wang 
mailto:wangshiyao2...@gmail.com>> wrote:

Dear FSL expert:
Firstly, I would like to thank for the reply from Douglas. Thank you for your 
suggestion! aparcstats2table is working!.

Then, I have another question about the brainstem substructures.
According to the guideline, 
https://surfer.nmr.mgh.harvard.edu/fswiki/MatlabRuntime
I download the environment and successfully installed. However, when I running 
command
" recon-all -s subject -brainstem-structures"

it shows wrong message

"ERROR: Flag -brainstem-structures unrecognized.
-s 201 -brainstem-structures"

So how can I fix it? Is that due to FSL version problem? If yes, how can I 
update to freesurfer 6.0?


thanks!
Lawrence
Emory.

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Re: [Freesurfer] using both T1/T2 and resolutions

2016-06-10 Thread Iglesias, Eugenio
Hi!
I actually sent out an email yesterday regarding this. The way that the 
subfield module is set up, you cannot take advantage of your full res T1 and 
your T1. We are working on a solution.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 10 Jun 2016, at 17:04, Matt Glasser 
mailto:m...@ma-tea.com>> wrote:

Hi Jim,

I would just use the HCP Pipelines for that: 
https://github.com/Washington-University/Pipelines, as they take care of all of 
those things re FreeSurfer.  I would set to using the 0.8mm templates so that 
nothing is down sampled.

Peace,

Matt.

From: 
mailto:freesurfer-boun...@nmr.mgh.harvard.edu>>
 on behalf of "Alexopoulos, Dimitrios" 
mailto:alexopoulo...@kids.wustl.edu>>
Reply-To: Freesurfer support list 
mailto:freesurfer@nmr.mgh.harvard.edu>>
Date: Friday, June 10, 2016 at 10:56 AM
To: "freesurfer@nmr.mgh.harvard.edu" 
mailto:freesurfer@nmr.mgh.harvard.edu>>
Subject: [Freesurfer] using both T1/T2 and resolutions

Hi,

We’d like to process pediatric data through the complete FS 5.3 pipeline. The 
T1/T2 data are acquired with a 3T Siemens as follows:
T1 mpr sag - 0.82x0.82x0.85
T2 Space - 1x1x1

We’d like to process using both the T1 and T2 (for better dura removal and 
possible myelin analysis).
Is it possible to use the hires T1 and have data not downsampled to 1x1x1? 
Ifpossible, can this be done in tandem with the lower resolution T2-space?

What recon-all command would be best for this process?

Jim


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unauthorized use, disclosure, copying, distribution or the taking of any action 
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Re: [Freesurfer] using both T1/T2 and resolutions

2016-06-10 Thread Iglesias, Eugenio
Oh gosh, you’re right Matt.
Sorry about this!

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 10 Jun 2016, at 18:54, Matt Glasser 
mailto:m...@ma-tea.com>> wrote:

Hi Eugenio,

I think he is just after cortical surfaces.

Matt.

From: 
mailto:freesurfer-boun...@nmr.mgh.harvard.edu>>
 on behalf of "Iglesias, Eugenio" 
mailto:e.igles...@ucl.ac.uk>>
Reply-To: Freesurfer support list 
mailto:freesurfer@nmr.mgh.harvard.edu>>
Date: Friday, June 10, 2016 at 12:30 PM
To: Freesurfer support list 
mailto:freesurfer@nmr.mgh.harvard.edu>>
Subject: Re: [Freesurfer] using both T1/T2 and resolutions

Hi!
I actually sent out an email yesterday regarding this. The way that the 
subfield module is set up, you cannot take advantage of your full res T1 and 
your T1. We are working on a solution.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 10 Jun 2016, at 17:04, Matt Glasser 
mailto:m...@ma-tea.com>> wrote:

Hi Jim,

I would just use the HCP Pipelines for that: 
https://github.com/Washington-University/Pipelines, as they take care of all of 
those things re FreeSurfer.  I would set to using the 0.8mm templates so that 
nothing is down sampled.

Peace,

Matt.

From: 
mailto:freesurfer-boun...@nmr.mgh.harvard.edu>>
 on behalf of "Alexopoulos, Dimitrios" 
mailto:alexopoulo...@kids.wustl.edu>>
Reply-To: Freesurfer support list 
mailto:freesurfer@nmr.mgh.harvard.edu>>
Date: Friday, June 10, 2016 at 10:56 AM
To: "freesurfer@nmr.mgh.harvard.edu<mailto:freesurfer@nmr.mgh.harvard.edu>" 
mailto:freesurfer@nmr.mgh.harvard.edu>>
Subject: [Freesurfer] using both T1/T2 and resolutions

Hi,

We’d like to process pediatric data through the complete FS 5.3 pipeline. The 
T1/T2 data are acquired with a 3T Siemens as follows:
T1 mpr sag - 0.82x0.82x0.85
T2 Space - 1x1x1

We’d like to process using both the T1 and T2 (for better dura removal and 
possible myelin analysis).
Is it possible to use the hires T1 and have data not downsampled to 1x1x1? 
Ifpossible, can this be done in tandem with the lower resolution T2-space?

What recon-all command would be best for this process?

Jim


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Information. If you are not the intended recipient, be advised that any 
unauthorized use, disclosure, copying, distribution or the taking of any action 
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Re: [Freesurfer] unit for hippocampus segmentation results

2016-06-16 Thread Iglesias, Eugenio
If you mean the new subfield module, then the answer is: cubic mm.


Juan Eugenio Iglesias

Translational Imaging Group

University College London

http://www.jeiglesias.com

http://cmictig.cs.ucl.ac.uk/



From: freesurfer-boun...@nmr.mgh.harvard.edu 
 on behalf of Fengji Geng 

Sent: Wednesday, June 15, 2016 8:34:09 PM
To: freesurfer@nmr.mgh.harvard.edu
Subject: [Freesurfer] unit for hippocampus segmentation results

Hi freesurfer experts,

We used the development version of freesurfer 6.0 to segment hippocampus. We 
are wondering what the unit is for the segmentation results.

Thanks,

--
Fengji Geng
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Re: [Freesurfer] Hippocampal Subfields Segmentation

2016-06-27 Thread Iglesias, Eugenio
Hi everyone,
you need to install the Matlab 2012b runtime as explained in the wiki:
https://surfer.nmr.mgh.harvard.edu/fswiki/MatlabRuntime
Cheers,
Eugenio



Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 27 Jun 2016, at 15:16, pierre deman 
mailto:deman.pie...@gmail.com>> wrote:

Hello,

I have similar problem. "
"Error:Cannot find CTF archive
/autofs/cluster/freesurfer/centos6_x86_64/dev/bin/segmentSubjectT1_autoEstimateAlveusML.ctf"
the file is here but when I try to execute it, it's always missing some library 
(libmwi18n.so for example, it was missing others before that I added on my 
computer, but it never ends)
I am on ubuntu 14.04.
I thought that the problem is linked to the matlab runtime. I installed the 
2012b. I tried newer version. installed again the 2012b.

Regards,
Pierre


On Mon, Jun 27, 2016 at 4:05 PM, Permesh Dhillon 
mailto:permesh.dhil...@nottingham.ac.uk>> 
wrote:
Hello FreeSurfer Developers,

I’m having issues with the hippocampal subfields segmentation using OS X 
Yosemite v10.10.5, Freesurfer dev version 6.0, Freesurfer  Subject Stamp: 
freesurfer-Linux-centos6_x86_64-stable-pub-v5.2.0   Current Stamp: 
freesurfer-Linux-centos6_x86_64-dev-20160616-8264611.

I ran the recon-all -s VE002 -hippocampal-subfields-T1 command and keep getting 
an error message : Error:CTF file 
'/usr/local/freesurfer-dev/bin/segmentSubjectT1_autoEstimateAlveusML.ctf' 
failed to open for 'Read' access. Error message: 'Open a zip file for 
read/modify failed.’

The segmented hippocampal files as described on free surfer wiki cannot be 
found under the subject ‘mri’ folder.
I understand other users have complained of a similar issue within the last 
week.

I’d ve grateful if you could assist me with the issue above.

Many thanks
Permesh


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Re: [Freesurfer] Hippocampal Subfields Segmentation

2016-06-27 Thread Iglesias, Eugenio
Hi Pierre,
Due to some technical problems, it might take me a couple of days to figure out 
what’s going on.  But it definitely sounds funny that it is asking for the CTF, 
since this is supposed to be embedded in the executable… I’ll get back to you 
as soon as possible.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 27 Jun 2016, at 15:32, pierre deman 
mailto:deman.pie...@gmail.com>> wrote:

I tried that. but didn't work.

Cheers,
Pierre

On Mon, Jun 27, 2016 at 4:32 PM, Iglesias, Eugenio 
mailto:e.igles...@ucl.ac.uk>> wrote:
Hi everyone,
you need to install the Matlab 2012b runtime as explained in the wiki:
https://surfer.nmr.mgh.harvard.edu/fswiki/MatlabRuntime
Cheers,
Eugenio



Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 27 Jun 2016, at 15:16, pierre deman 
mailto:deman.pie...@gmail.com>> wrote:

Hello,

I have similar problem. "
"Error:Cannot find CTF archive
/autofs/cluster/freesurfer/centos6_x86_64/dev/bin/segmentSubjectT1_autoEstimateAlveusML.ctf"
the file is here but when I try to execute it, it's always missing some library 
(libmwi18n.so for example, it was missing others before that I added on my 
computer, but it never ends)
I am on ubuntu 14.04.
I thought that the problem is linked to the matlab runtime. I installed the 
2012b. I tried newer version. installed again the 2012b.

Regards,
Pierre


On Mon, Jun 27, 2016 at 4:05 PM, Permesh Dhillon 
mailto:permesh.dhil...@nottingham.ac.uk>> 
wrote:
Hello FreeSurfer Developers,

I’m having issues with the hippocampal subfields segmentation using OS X 
Yosemite v10.10.5, Freesurfer dev version 6.0, Freesurfer  Subject Stamp: 
freesurfer-Linux-centos6_x86_64-stable-pub-v5.2.0   Current Stamp: 
freesurfer-Linux-centos6_x86_64-dev-20160616-8264611.

I ran the recon-all -s VE002 -hippocampal-subfields-T1 command and keep getting 
an error message : Error:CTF file 
'/usr/local/freesurfer-dev/bin/segmentSubjectT1_autoEstimateAlveusML.ctf' 
failed to open for 'Read' access. Error message: 'Open a zip file for 
read/modify failed.’

The segmented hippocampal files as described on free surfer wiki cannot be 
found under the subject ‘mri’ folder.
I understand other users have complained of a similar issue within the last 
week.

I’d ve grateful if you could assist me with the issue above.

Many thanks
Permesh

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Mobile : +33 7 82 57 80 94
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Re: [Freesurfer] Hippocampal Subfields Segmentation

2016-06-29 Thread Iglesias, Eugenio
I could finally look into this. It is indeed weird. The CTF is indeed embedded 
in the executable…
Zeke/Nick, can you shed some light on this?
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 27 Jun 2016, at 15:43, Iglesias, Eugenio 
mailto:e.igles...@ucl.ac.uk>> wrote:

Hi Pierre,
Due to some technical problems, it might take me a couple of days to figure out 
what’s going on.  But it definitely sounds funny that it is asking for the CTF, 
since this is supposed to be embedded in the executable… I’ll get back to you 
as soon as possible.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 27 Jun 2016, at 15:32, pierre deman 
mailto:deman.pie...@gmail.com>> wrote:

I tried that. but didn't work.

Cheers,
Pierre

On Mon, Jun 27, 2016 at 4:32 PM, Iglesias, Eugenio 
mailto:e.igles...@ucl.ac.uk>> wrote:
Hi everyone,
you need to install the Matlab 2012b runtime as explained in the wiki:
https://surfer.nmr.mgh.harvard.edu/fswiki/MatlabRuntime
Cheers,
Eugenio



Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 27 Jun 2016, at 15:16, pierre deman 
mailto:deman.pie...@gmail.com>> wrote:

Hello,

I have similar problem. "
"Error:Cannot find CTF archive
/autofs/cluster/freesurfer/centos6_x86_64/dev/bin/segmentSubjectT1_autoEstimateAlveusML.ctf"
the file is here but when I try to execute it, it's always missing some library 
(libmwi18n.so for example, it was missing others before that I added on my 
computer, but it never ends)
I am on ubuntu 14.04.
I thought that the problem is linked to the matlab runtime. I installed the 
2012b. I tried newer version. installed again the 2012b.

Regards,
Pierre


On Mon, Jun 27, 2016 at 4:05 PM, Permesh Dhillon 
mailto:permesh.dhil...@nottingham.ac.uk>> 
wrote:
Hello FreeSurfer Developers,

I’m having issues with the hippocampal subfields segmentation using OS X 
Yosemite v10.10.5, Freesurfer dev version 6.0, Freesurfer  Subject Stamp: 
freesurfer-Linux-centos6_x86_64-stable-pub-v5.2.0   Current Stamp: 
freesurfer-Linux-centos6_x86_64-dev-20160616-8264611.

I ran the recon-all -s VE002 -hippocampal-subfields-T1 command and keep getting 
an error message : Error:CTF file 
'/usr/local/freesurfer-dev/bin/segmentSubjectT1_autoEstimateAlveusML.ctf' 
failed to open for 'Read' access. Error message: 'Open a zip file for 
read/modify failed.’

The segmented hippocampal files as described on free surfer wiki cannot be 
found under the subject ‘mri’ folder.
I understand other users have complained of a similar issue within the last 
week.

I’d ve grateful if you could assist me with the issue above.

Many thanks
Permesh

This message and any attachment are intended solely for the addressee
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author of this email do not necessarily reflect the views of the
University of Nottingham.

This message has been checked for viruses but the contents of an
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Mobile : +33 7 82 57 80 94
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Re: [Freesurfer] Hippocampal Subfields Segmentation

2016-07-06 Thread Iglesias, Eugenio
Dear all,

We are working on this; I'll write again when the problem is solved (hopefully 
soon!)

Cheers

Eugenio


Juan Eugenio Iglesias

Translational Imaging Group

University College London

http://www.jeiglesias.com

http://cmictig.cs.ucl.ac.uk/



From: freesurfer-boun...@nmr.mgh.harvard.edu 
 on behalf of pierre deman 

Sent: Tuesday, July 5, 2016 7:04:21 PM
To: Freesurfer support list
Subject: Re: [Freesurfer] Hippocampal Subfields Segmentation


Hi,
I still have a problem as well with the subfields segmentation (ubuntu 14.04, 
with the files .ctf)

Cheers,
Pierre

Hello FreeSurfer Experts,

I'm having issues with the hippocampal subfields segmentation using OS X 
Yosemite v10.10.5, Freesurfer dev version 6.0, Freesurfer  Subject Stamp: 
freesurfer-Linux-centos6_x86_64-stable-pub-v5.2.0   Current Stamp: 
freesurfer-Linux-centos6_x86_64-dev-20160616-8264611.

I ran the recon-all -s VE002 -hippocampal-subfields-T1 command and keep getting 
an error message : Error:CTF file 
'/usr/local/freesurfer-dev/bin/segmentSubjectT1_autoEstimateAlveusML.ctf' 
failed to open for 'Read' access. Error message: 'Open a zip file for 
read/modify failed.'

The segmented hippocampal files as described on free surfer wiki cannot be 
found under the subject 'mri' folder.
I understand other users have complained of a similar issue within the last 
week.

I'd ve grateful if you could assist me with the issue above.

Many thanks
Permesh




This message and any attachment are intended solely for the addressee
and may contain confidential information. If you have received this
message in error, please send it back to me, and immediately delete it.

Please do not use, copy or disclose the information contained in this
message or in any attachment.  Any views or opinions expressed by the
author of this email do not necessarily reflect the views of the
University of Nottingham.

This message has been checked for viruses but the contents of an
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Re: [Freesurfer] hippocampal subfields command

2016-07-06 Thread Iglesias, Eugenio
Hi Jim,
the latter command uses a new, higher resolution atlas based on ex vivo scans.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 6 Jul 2016, at 15:39, Alexopoulos, Dimitrios 
mailto:alexopoulo...@kids.wustl.edu>> wrote:

A quick question re: hippocampal segmentation.

I have processed 1mm isotropic T1 data with 5.3 using the following command:
recon-all  -qcache -all  -hippo-subfields

How is this this different than using the following command I have found here: 
https://surfer.nmr.mgh.harvard.edu/fswiki/HippocampalSubfields
-hippocampal-subfields-T1


Thanks.
Jim


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Re: [Freesurfer] Hippocampal subfields segmentation - what is the voxel size of the input?

2016-07-06 Thread Iglesias, Eugenio
Not yet, sorry. But it’s on my todo list.


Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 6 Jul 2016, at 14:39, Hibert, Matthew Louis 
mailto:mhib...@mgh.harvard.edu>> wrote:

Hi Eugenio,
Have you had a chance to look into the possibility of combining the -hires flag 
with the hippocampal subfield segmentation?

Thanks,
Matt

From: 
freesurfer-boun...@nmr.mgh.harvard.edu<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 
[freesurfer-boun...@nmr.mgh.harvard.edu<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>]
 on behalf of Iglesias, Eugenio 
[e.igles...@ucl.ac.uk<mailto:e.igles...@ucl.ac.uk>]
Sent: Friday, June 10, 2016 3:36 AM
To: Freesurfer support list
Subject: Re: [Freesurfer] Hippocampal subfields segmentation - what is the 
voxel size of the input?

Hi Matt,
Bruce actually mentioned this possibility yesterday. Good to hear it doesn’t 
crash when you run it! That said, I need to go through the code, and make sure 
that data are handled the way they are supposed to: the fact that it doesn’t 
crash doesn’t directly imply that it is working properly. Hopefully I’ll find 
time to do this next week…
Cheers,
Eugenio


Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 9 Jun 2016, at 21:51, Hibert, Matthew Louis 
mailto:mhib...@mgh.harvard.edu>> wrote:

Hi Eugenio,
Would it also be possible to use the -hires flag in the initial recon-all 
command to prevent the T1 from being downsampled and maintain the voxel size 
that the T1 was acquired at, and use that resulting recon for the hippocampal 
subfield segmentation?  I've tested this with MEMPRAGE scans acquired at 0.75mm 
isotropic and coronal T2 anisotropic scans acquired at 0.33mm in plane with 1mm 
thick slices, and the results look reasonable.  The "1mm" label files are 
correctly downsampled to 0.75mm instead of 1mm, and the higher resolution label 
files remain at 0.33mm resolution.

Thanks,
Matt

Stufflebeam Lab
Athinoula A. Martinos Center
Massachusetts General Hospital
149 13th Street, Room 1115S
Charlestown, MA 02129

From: 
freesurfer-boun...@nmr.mgh.harvard.edu<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 
[freesurfer-boun...@nmr.mgh.harvard.edu<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>]
 on behalf of Iglesias, Eugenio 
[e.igles...@ucl.ac.uk<mailto:e.igles...@ucl.ac.uk>]
Sent: Thursday, June 09, 2016 2:36 PM
To: Freesurfer support list
Subject: Re: [Freesurfer] Hippocampal subfields segmentation - what is the 
voxel size of the input?

Hi Fernando,

Unfortunately, FreeSurfer does downsample the T1s to 1mm, and the subfield code 
assumes that the T1 comes from FreeSurfer… For the paper, I hacked the code to 
take advantage of multiple images with higher resolution, but it hasn’t been 
thoroughly tested and it’s not publicly available at this point.
That said, there are different things you can do at this point:
1. Use the T1+T2 as is (disadvantage: T1 will be resampled to 1 mm).
2. Use only the T2.
3. Use only the T1. To do this, you would use the T1 as additional scan on its 
own (i.e., the main and additional scans are the same, but the additional one 
won’t be resampled).
4. There might be a way (hack) of using both scans at full resolution. If you 
change the header of the T1 scan and specify that the voxel size is 1mm, no 
resampling will happen; FreeSurfer will believe that you’re dealing with a 
subject with a very large head. If you do this, you’ll also have to enlarge the 
voxel size of the T2 by a factor 1/0.7. Also, the resulting volumes will have 
to be divided by (1/0.7)^3 in order to correct for the “wrong” voxel size.

I hope this helps!

Cheers,

Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 9 Jun 2016, at 19:23, Fernando Pasquini Santos 
mailto:fernandop...@gmail.com>> wrote:

Dear,

I have a doubt regarding the input T1 image used for the Hippocampal Subfield 
segmentation in Freesurfer 6.0 - 
https://surfer.nmr.mgh.harvard.edu/fswiki/HippocampalSubfields

In this documentation it says that I can use a standard 1mm T1 image or the 
same standard 1mm T1 image with an additional scan. However, I want to use a 
0.7mm T1 image as input, with an additional T2 scan. When I run the program 
with it, the output images (nu.mgz and orig.mgz) are downsampled to 1mm voxel 
size. So, I don't know if this happens just because of the recon-all program or 
if the segmentation is being done in the downsampled T1 image or in the 
original 0.7mm.

By reading the article "A computational atlas of the hippocampal formation 
using ex vivo, ultra-high resolution MRI: Ap

Re: [Freesurfer] {Filename?} Hippocampal subfields --> Can't find a *ctf file?

2016-07-08 Thread Iglesias, Eugenio
I think I identified the problem; hopefully this will be sorted out very soon.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 7 Jul 2016, at 19:23, Perea Camargo, Rodrigo Dennis 
mailto:rpereacama...@mgh.harvard.edu>> wrote:


Warning: This message has had one or more attachments removed (recon-all.cmd). 
Please read the "UCL-Attachment-Warning.txt" attachment(s) for more information.

Hi all,
I am currently trying to run hippocampal subfields in a couple of my 
participants using FreeSurfer6.0 (located at 
*nmr*:/usr/local/freesurfer/stable6).

It did run successfully for many of my subjects earlier in the year but some of 
them only had a let hemisphere segmentation. So I decided to re-run them using 
launchpad and also my local nmr computer.

Now, none of the hippocampal sufields segmentations appear (no 
rh/lh.hippoSfLabels-T1-T2.*.mgz appears). I looked at 
/scripts/scripts/hippocampal-subfields-T1T2.log and the error I get 
is:

Error:Cannot find CTF archive 
/autofs/cluster/freesurfer/centos6_x86_64/stable6/bin/segmentSubjectT1T2_autoEstimateAlveusML.ctf


Could a missing *.ctf  cause the error? (btw, the re-run happened after the 
major hardware crash).

Thanks in advance for your help,
Rodrigo

PS: I am attaching the *log files as suggested in the bug reporting page.


---
Rodrigo Dennis Perea
Research Fellow
Department of Radiology
Athinoula A. Martinos Center
Massachusetts General Hospital
rpereacama...@mgh.harvard.edu






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Re: [Freesurfer] Hippocampal subfields --> Can't find a *ctf file?

2016-07-13 Thread Iglesias, Eugenio
Dear all,
our expert developer Zeke Kaufman figured out what the problem was. We have now 
fixed the Linux version; the MAC version will hopefully be ready as well in a 
couple of days. I have also fixed other bugs (including the problem that caused 
the code to get stuck every once in a while).
You can downloaded the latest development version from our website.
Thanks everyone for your feedback.
Cheers,
Eugenio



Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 8 Jul 2016, at 12:14, Iglesias, Eugenio 
mailto:e.igles...@ucl.ac.uk>> wrote:

I think I identified the problem; hopefully this will be sorted out very soon.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 7 Jul 2016, at 19:23, Perea Camargo, Rodrigo Dennis 
mailto:rpereacama...@mgh.harvard.edu>> wrote:


Warning: This message has had one or more attachments removed (recon-all.cmd). 
Please read the "UCL-Attachment-Warning.txt" attachment(s) for more information.

Hi all,
I am currently trying to run hippocampal subfields in a couple of my 
participants using FreeSurfer6.0 (located at 
*nmr*:/usr/local/freesurfer/stable6).

It did run successfully for many of my subjects earlier in the year but some of 
them only had a let hemisphere segmentation. So I decided to re-run them using 
launchpad and also my local nmr computer.

Now, none of the hippocampal sufields segmentations appear (no 
rh/lh.hippoSfLabels-T1-T2.*.mgz appears). I looked at 
/scripts/scripts/hippocampal-subfields-T1T2.log and the error I get 
is:

Error:Cannot find CTF archive 
/autofs/cluster/freesurfer/centos6_x86_64/stable6/bin/segmentSubjectT1T2_autoEstimateAlveusML.ctf


Could a missing *.ctf  cause the error? (btw, the re-run happened after the 
major hardware crash).

Thanks in advance for your help,
Rodrigo

PS: I am attaching the *log files as suggested in the bug reporting page.


---
Rodrigo Dennis Perea
Research Fellow
Department of Radiology
Athinoula A. Martinos Center
Massachusetts General Hospital
rpereacama...@mgh.harvard.edu<mailto:rpereacama...@mgh.harvard.edu>






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Re: [Freesurfer] Hippocampal subfields --> Can't find a *ctf file?

2016-07-13 Thread Iglesias, Eugenio
And thanks to Zeke, of course ;-)


Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 13 Jul 2016, at 11:19, Iglesias, Eugenio 
mailto:e.igles...@ucl.ac.uk>> wrote:

Dear all,
our expert developer Zeke Kaufman figured out what the problem was. We have now 
fixed the Linux version; the MAC version will hopefully be ready as well in a 
couple of days. I have also fixed other bugs (including the problem that caused 
the code to get stuck every once in a while).
You can downloaded the latest development version from our website.
Thanks everyone for your feedback.
Cheers,
Eugenio



Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 8 Jul 2016, at 12:14, Iglesias, Eugenio 
mailto:e.igles...@ucl.ac.uk>> wrote:

I think I identified the problem; hopefully this will be sorted out very soon.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 7 Jul 2016, at 19:23, Perea Camargo, Rodrigo Dennis 
mailto:rpereacama...@mgh.harvard.edu>> wrote:


Warning: This message has had one or more attachments removed (recon-all.cmd). 
Please read the "UCL-Attachment-Warning.txt" attachment(s) for more information.

Hi all,
I am currently trying to run hippocampal subfields in a couple of my 
participants using FreeSurfer6.0 (located at 
*nmr*:/usr/local/freesurfer/stable6).

It did run successfully for many of my subjects earlier in the year but some of 
them only had a let hemisphere segmentation. So I decided to re-run them using 
launchpad and also my local nmr computer.

Now, none of the hippocampal sufields segmentations appear (no 
rh/lh.hippoSfLabels-T1-T2.*.mgz appears). I looked at 
/scripts/scripts/hippocampal-subfields-T1T2.log and the error I get 
is:

Error:Cannot find CTF archive 
/autofs/cluster/freesurfer/centos6_x86_64/stable6/bin/segmentSubjectT1T2_autoEstimateAlveusML.ctf


Could a missing *.ctf  cause the error? (btw, the re-run happened after the 
major hardware crash).

Thanks in advance for your help,
Rodrigo

PS: I am attaching the *log files as suggested in the bug reporting page.


---
Rodrigo Dennis Perea
Research Fellow
Department of Radiology
Athinoula A. Martinos Center
Massachusetts General Hospital
rpereacama...@mgh.harvard.edu<mailto:rpereacama...@mgh.harvard.edu>






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Re: [Freesurfer] Hippocampal subfields total volume differences

2016-07-13 Thread Iglesias, Eugenio
Hi Mojmir,
ASEG typically gives a larger estimate of the volume, though highly correlated 
with that from the subfield package. We have found the measurements from the 
subfield package to be a bit more reliable, though.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 13 Jul 2016, at 16:07, Mojmír Vinkler 
mailto:mojmir.vink...@gmail.com>> wrote:

Hi experts,

I'm using Freesurfer 6.0 dev version (Mac) to perform hippocampal subfields 
segmentation. I only need to measure total hippocampus volume, but measurements 
from basic `recon-all` were too volatile and I was hoping that using subfields 
with T2 modality would reduce variance. However, volume measured by hippocampal 
subfields is significantly different from volume in aseg.stats.

Here are volumes for right hippocampus from various methods:
aseg.stats - 3312.8
rh.hippoSfVolumes-T1.v10.txt (Mode A - only T1 used) - 2883.8
rh.hippoSfVolumes-T2.v10.txt (Mode B - using only additional scan) - 2503.97
rh.hippoSfVolumes-T1-T1T2.v10.txt (Mode B - Multispectral segmentation) - 
2596.09

I checked labeling visually and there were no obvious problems. Is such a large 
difference common? Am I missing something? What number should be most trusted?

Thanks for any hints!
Mojmir
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Re: [Freesurfer] Hippocampal subfields --> Can\'t find a *ctf file?

2016-07-14 Thread Iglesias, Eugenio
Dear Fernando,
Are you using the MAC version? I haven’t finished fixing the bugs in that one 
yet.
If you’re using the Linux version: Zeke, can you please shed some light on what 
the problem might be?
Cheers,
Eugenio



Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 14 Jul 2016, at 08:57, Fernando Pérez-García 
mailto:fepe...@gmail.com>> wrote:

Dear Eugenio,

I'm still having this issue, even after downloading the latest development 
version from the website as you suggested. My steps (yesterday):

  1.  Download and install FS (dev version)
  2.  Run recon-all
  3.  Download and install Matlab runtime
  4.  Run recon-all with brainstem structures

I get the following error:

Error:Cannot find CTF archive /usr/local/freesurfer/bin/SegmentSubject.bin.ctf


Should I try the same steps again today?


Best,

Fernando

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Re: [Freesurfer] Hippocampal subfields --> Can\'t find a *ctf file?

2016-07-14 Thread Iglesias, Eugenio
The MAC version is now fixed as well. It should be available for download in 
the next couple of days (Zeke can provide a better estimate).
Thanks again to all of you for your feedback.
/E


Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 14 Jul 2016, at 10:05, Fernando Pérez-García 
mailto:fepe...@gmail.com>> wrote:

I am using Ubuntu 14.04.4.
Please let me know if you need some more info.

Cheers,
Fernando

2016-07-14 10:59 GMT+02:00 Iglesias, Eugenio 
mailto:e.igles...@ucl.ac.uk>>:
Dear Fernando,
Are you using the MAC version? I haven’t finished fixing the bugs in that one 
yet.
If you’re using the Linux version: Zeke, can you please shed some light on what 
the problem might be?
Cheers,
Eugenio



Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 14 Jul 2016, at 08:57, Fernando Pérez-García 
mailto:fepe...@gmail.com>> wrote:

Dear Eugenio,

I'm still having this issue, even after downloading the latest development 
version from the website as you suggested. My steps (yesterday):

  1.  Download and install FS (dev version)
  2.  Run recon-all
  3.  Download and install Matlab runtime
  4.  Run recon-all with brainstem structures

I get the following error:

Error:Cannot find CTF archive /usr/local/freesurfer/bin/SegmentSubject.bin.ctf


Should I try the same steps again today?


Best,

Fernando



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Re: [Freesurfer] Hippocampal subfields total volume differences

2016-07-15 Thread Iglesias, Eugenio
Dear Mojmir,
using ~400 subjects, we found that the subfield module was a bit better than 
the ASEG volumes at discriminating Alzheimer’s patients from controls (see the 
Neuorimage paper). But, in any case, the difference is small.
Regarding longitudinal segmentation: we just got a paper about this accepted, 
see
http://www.nmr.mgh.harvard.edu/~iglesias/pdf/Neuroimage_2016_longitudinal.pdf
I still need to find time to clean up the code and put it up on FreeSurfer. For 
the time being, you can run the subfield module on the longitudinally analyzed 
recons (method “L-INIT” in the paper).
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 15 Jul 2016, at 09:00, Mojmír Vinkler 
mailto:mojmir.vink...@gmail.com>> wrote:

Hi Juan,

Thanks! You're right, they really are tightly correlated (although their 
absolute values differ by 30%). We tried it on couple of subjects, but didn't 
find subfields to be significantly better than aseg stats though. By the way, 
is Freesurfer capable of using multiple scans from the same subject 
(longitudinal study, same modality) to make more precise measurements? For 
example by using T1 from the same subject / different time instead of T2 in 
subfields?

Thanks!
Mojmir

On Wed, Jul 13, 2016 at 5:15 PM Iglesias, Eugenio 
mailto:e.igles...@ucl.ac.uk>> wrote:
Hi Mojmir,
ASEG typically gives a larger estimate of the volume, though highly correlated 
with that from the subfield package. We have found the measurements from the 
subfield package to be a bit more reliable, though.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 13 Jul 2016, at 16:07, Mojmír Vinkler 
mailto:mojmir.vink...@gmail.com>> wrote:

Hi experts,

I'm using Freesurfer 6.0 dev version (Mac) to perform hippocampal subfields 
segmentation. I only need to measure total hippocampus volume, but measurements 
from basic `recon-all` were too volatile and I was hoping that using subfields 
with T2 modality would reduce variance. However, volume measured by hippocampal 
subfields is significantly different from volume in aseg.stats.

Here are volumes for right hippocampus from various methods:
aseg.stats - 3312.8
rh.hippoSfVolumes-T1.v10.txt (Mode A - only T1 used) - 2883.8
rh.hippoSfVolumes-T2.v10.txt (Mode B - using only additional scan) - 2503.97
rh.hippoSfVolumes-T1-T1T2.v10.txt (Mode B - Multispectral segmentation) - 
2596.09

I checked labeling visually and there were no obvious problems. Is such a large 
difference common? Am I missing something? What number should be most trusted?

Thanks for any hints!
Mojmir
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Re: [Freesurfer] Hippocampal subfields --> Can't find a *ctf file?

2016-07-20 Thread Iglesias, Eugenio
Thanks a lot, Pierre.
I’ll get this sorted out as soon as possible.  I’m in the process of modifying 
the module so it supports data with resolution >1mm, and also incorporating the 
longitudinal segmentation method described in 
https://doi.org/10.1016/j.neuroimage.2016.07.020
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 20 Jul 2016, at 09:57, pierre deman 
mailto:deman.pie...@gmail.com>> wrote:

Hi,

I downloaded the new freesurfer development version and I still have the same 
problem when running the hippocampal-subfields

"Invalid MEX-file 
'/tmp/MCR_4195017647/.mcrCache8.0/segmen0/autofs/cluster/koen/koen/GEMS-Release/bin/kvlGEMSMatlab.mexa64':
 libkvlGEMSCommon.so: cannot open shared object file: No such file or directory
Error in kvlClear (line 11)

Error in segmentSubjectT1_autoEstimateAlveusML (line 133)

MATLAB:invalidMEXFile".

Does anyone have any idea about a solution ?

Cheers,
Pierre


On Wed, Jul 13, 2016 at 12:22 PM, Iglesias, Eugenio 
mailto:e.igles...@ucl.ac.uk>> wrote:
And thanks to Zeke, of course ;-)


Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 13 Jul 2016, at 11:19, Iglesias, Eugenio 
mailto:e.igles...@ucl.ac.uk>> wrote:

Dear all,
our expert developer Zeke Kaufman figured out what the problem was. We have now 
fixed the Linux version; the MAC version will hopefully be ready as well in a 
couple of days. I have also fixed other bugs (including the problem that caused 
the code to get stuck every once in a while).
You can downloaded the latest development version from our website.
Thanks everyone for your feedback.
Cheers,
Eugenio



Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 8 Jul 2016, at 12:14, Iglesias, Eugenio 
mailto:e.igles...@ucl.ac.uk>> wrote:

I think I identified the problem; hopefully this will be sorted out very soon.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 7 Jul 2016, at 19:23, Perea Camargo, Rodrigo Dennis 
mailto:rpereacama...@mgh.harvard.edu>> wrote:


Warning: This message has had one or more attachments removed (recon-all.cmd). 
Please read the "UCL-Attachment-Warning.txt" attachment(s) for more information.

Hi all,
I am currently trying to run hippocampal subfields in a couple of my 
participants using FreeSurfer6.0 (located at 
*nmr*:/usr/local/freesurfer/stable6).

It did run successfully for many of my subjects earlier in the year but some of 
them only had a let hemisphere segmentation. So I decided to re-run them using 
launchpad and also my local nmr computer.

Now, none of the hippocampal sufields segmentations appear (no 
rh/lh.hippoSfLabels-T1-T2.*.mgz appears). I looked at 
/scripts/scripts/hippocampal-subfields-T1T2.log and the error I get 
is:

Error:Cannot find CTF archive 
/autofs/cluster/freesurfer/centos6_x86_64/stable6/bin/segmentSubjectT1T2_autoEstimateAlveusML.ctf


Could a missing *.ctf  cause the error? (btw, the re-run happened after the 
major hardware crash).

Thanks in advance for your help,
Rodrigo

PS: I am attaching the *log files as suggested in the bug reporting page.


---
Rodrigo Dennis Perea
Research Fellow
Department of Radiology
Athinoula A. Martinos Center
Massachusetts General Hospital
rpereacama...@mgh.harvard.edu<mailto:rpereacama...@mgh.harvard.edu>






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Re: [Freesurfer] New hippocampal subfields

2016-07-26 Thread Iglesias, Eugenio
It need to run some additional tests, but I'm almost sure it is solved. The 
fixed code will be in the development version very soon, with some other 
updates. Stay tuned!

Cheers,

Eugenio


Juan Eugenio Iglesias

Translational Imaging Group

University College London

http://www.jeiglesias.com

http://cmictig.cs.ucl.ac.uk/



From: freesurfer-boun...@nmr.mgh.harvard.edu 
 on behalf of Jin Kyu Gahm 

Sent: Tuesday, July 26, 2016 10:17:08 PM
To: freesurfer@nmr.mgh.harvard.edu
Subject: [Freesurfer] New hippocampal subfields

Hello,

I was trying the new segmentation module of hippocampal subfields, but I also 
encountered the same errors as Pierre reported a week ago:

--
Invalid MEX-file 
'/tmp/MCR_1031368111/.mcrCache8.0/segmen0/autofs/cluster/koen/koen/GEMS-Release/bin/kvlGEMSMatlab.mexa64':
 libkvlGEMSCommon.so: cannot open shared object file: No such file or directory

Error in kvlClear (line 11)

Error in segmentSubjectT1_autoEstimateAlveusML (line 133)
--

Eugenio - I wonder if you already solved the problem. Thanks for your help!

Best,
Jin

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Re: [Freesurfer] Recent error in the dev version

2016-07-27 Thread Iglesias, Eugenio
Hi Daniel,
the problems was that I accidentally compiled the module against dynamic rather 
than static libraries. The code will be fixed in the development version very 
soon.
Also, I introduced some changes in the code so that it can handle high 
resolution T1s, but the behaviour on standard resolution T1 data hasn’t changed.
I hope this helps.
Cheers,
Eugenio 

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


> On 27 Jul 2016, at 20:49, Liu, Daniel  wrote:
> 
> Hi,
> 
> I'm an undergraduate learning about/working with freesurfer as part of my 
> summer research project.  In early-mid June I downloaded the dev version of 
> Freesurfer to use on my mac.  When I ran it at that time, I had no problem.  
> Recently I started working on a cluster computer (linux) and got the same 
> problem outlined in this exchange:
> 
> https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg48412.html.
> 
> 
> I was wondering if I could get an update on this and possibly an explanation 
> as to what the problem was.  I was told that the dev version on the cluster 
> was updated today (with the fixed version as mentioned in the email) but I 
> still got that message after running the program.
> 
> 
> Also, were there any major changes to the program that I should be aware 
> about in terms affecting data analysis of the MRI patient data for the 
> hippocampus subfields tool?
> 
> 
> If you could let me know, it would be appreciated.
> 
> 
> Thanks,
> 
> 
> Daniel
> 
> 
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Re: [Freesurfer] V6.0 Hippocampal subfield segmentation

2016-07-27 Thread Iglesias, Eugenio
Dear Xiaowei,
That beta version was taken down because it had several problems. I would 
recommend that you wait until the next beta comes out (hopefully in 2 weeks or 
so), or that you download the development version (in that case, I’d do it next 
week because we currently fixing an error I accidentally introduced in the 
hippocampal subfield module).
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 27 Jul 2016, at 20:23, Zhuang, Xiaowei 
mailto:zhua...@ccf.org>> wrote:

Hi everyone,

I am running the new hippocampal subfield segmentation with a V6.0 beta version 
released last year on 20150724.

There is only 1 subject (out of about 40 total) exit with an ERROR during 
segmentation with T1 input. All others subjects ran through the hippocampal 
segmentation and gives me reasonable results.

And the same T1 image ran through the V5.3 old hippocampal segmentation so I 
believe there is nothing wrong with image itself.

I am wondering is this a bug in the beta version of V6.0 I am having? And I 
have attached the two ERROR log files. Any response will be appreciated.

Thanks,
Xiaowei.





Xiaowei Zhuang   |  Research Engineer  |  Lou Ruvo Center for Brain Health
 Cleveland Clinic  |  888 W Bonneville Ave.   |  Las Vegas, NV 89106  | (702) 
685-6051




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Re: [Freesurfer] Freesurfer dev version

2016-08-01 Thread Iglesias, Eugenio
Hi Daniel,
The issue is fixed, but I don’t know if the updated version is already in dev.
Zeke, can you shed some light on this?
Cheers,
/Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 1 Aug 2016, at 19:49, Liu, Daniel mailto:d...@mcw.edu>> wrote:

It was the invalid MEX file problem mentioned in this exchange 
https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg48412.html

I was told it would be fixed sometime this week in the dev version (and in 2 
weeks when the next beta version was released).

Thanks,

Daniel

From: 
freesurfer-boun...@nmr.mgh.harvard.edu
 
mailto:freesurfer-boun...@nmr.mgh.harvard.edu>>
 on behalf of Bruce Fischl 
mailto:fis...@nmr.mgh.harvard.edu>>
Sent: Monday, August 1, 2016 11:04 AM
To: Freesurfer support list
Subject: Re: [Freesurfer] Freesurfer dev version

which error? The mri_normalize problem? If so, then yes I believe that is
now fixed
On Mon, 1 Aug 2016, Liu, Daniel wrote:

Hi,


I wanted to follow up on the error that came up in the freesurfer dev version 
this past week.  Has it been fixed yet?  If so, has the link to the download 
page been changed?  The one I booked marked does not lead me to the page 
anymore and I would appreciate it if you could direct me to the correct 
location.


Thanks,


Daniel

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[Freesurfer] recent problems with hippocampal subfield and brainstem modules

2016-08-05 Thread Iglesias, Eugenio
Dear users,

Many of you have recently experienced problems with the hippocampal subfield 
and brainstem substructure segmentation modules. These modules have been broken 
in the dev version for a couple of weeks. All the problems have now been fixed 
internally. The updates will be incorporated to the dev version on the website 
as soon as possible. So, if your subfield module is not working, just wait for 
a few days (I would say late next week, to be on the safe side), and try 
downloading the dev version again.

On a happier note, we have added some new features to the modules:
1. They can now segment high resolution T1s that have been processed with 
recon-all -cm
2. There is now a longitudinal version of the hippocampal subfield segmentation 
module:
https://surfer.nmr.mgh.harvard.edu/fswiki/LongitudinalHippocampalSubfields
based on our recent Neuroimage paper: “Bayesian longitudinal segmentation of 
hippocampal substructures in brain MRI using subject-specific atlases”

Apologies to everyone for the inconvenience, and special thanks to our 
developer Zeke Kaufman for all the work.

Eugenio



Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


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Re: [Freesurfer] output with input matrix size and referential

2016-08-10 Thread Iglesias, Eugenio
You can always run mri_convert with the -rl (“reslice like”) flag to achieve 
this. Something like: mri_convert input.mgz output.mgz -rl reference.mgz -odt 
float
If it’s a segmentation volume, you should add -rt nearest, in order to use 
nearest neighbor interpolation.
Cheers,
Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 10 Aug 2016, at 13:31, pierre deman 
mailto:deman.pie...@gmail.com>> wrote:

Hello,

I am trying to have the atlases aparc.a2009+aseg.mgz, hippocampal subfield etc 
...
in a matrix with the same size as the input of recon-all (and not the cubic 
matrix 256x256x256) and with the same orientation.

what is the best way to do it ?

Cheers,
Pierre

--
DEMAN Pierre
Mobile : +33 7 82 57 80 94
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Re: [Freesurfer] dividing Freesufer subfields into one anterior, middle and posterior region

2016-08-15 Thread Iglesias, Eugenio
Hi Erik,

there’s no FreeSurfer program to do this in a straightforward manner. But you 
can:

1. read in the hippocampal subfield segmentation  into matlab with the MRIread 
function in the $FREESURFER_HOME/matlab directory.
2. extract the major axis with the hippocampus using PCA.
3. Subdivide the subfields along that axis

You can find code to do 2 and 3 here: https://github.com/garikoitz/hippovol

Cheers,

/Eugenio

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 15 Aug 2016, at 17:26, Erik Lindberg 
mailto:erikoloflindb...@gmail.com>> wrote:

Dear FS experts. I want to divid the FS subfield segementation into a anterior 
part, one middle part and posterior segment - or potentially divide the rang 
into 10% of the whole rang - and then move backword until I extracted 10 
subparts.

Is there some way I can do that?

Thanks
Erik
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Re: [Freesurfer] version 6 NOT released yet

2016-08-24 Thread Iglesias, Eugenio
You can! It just makes your results harder to reproduce (running recon-all with 
one version, and the subfields with the other).

Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 24 Aug 2016, at 17:01, Douglas Greve 
mailto:gr...@nmr.mgh.harvard.edu>> wrote:


I don't know. This is a question for Eugenio

On 8/24/16 11:53 AM, pedrogomesr...@gmail.com 
wrote:
Hi, Doug.
Is it possible to run FreeSurfer 6 Hippocampal-subfields on FreeSurfer 5.3 
recons, or this also should not be done?
Best,
Pedro Rosa.

On Aug 24, 2016, at 11:58, Douglas Greve 
mailto:gr...@nmr.mgh.harvard.edu>> wrote:


PLEASE DO NOT USE ANYTHING LABELLED AS "6.0" FOR ANYTHING OTHER THAN
TESTING. WHEN WE RELEASE 6.0 WE WILL MAKE AN ANNOUNCEMENT.

Thanks

The FreeSurfer Team


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Re: [Freesurfer] Brainstem nucleus

2016-08-30 Thread Iglesias, Eugenio
Hi Mohamad,
For now, our brainstem module separates this structure into midbrain, pons, 
medulla and SCP - please see this link:
https://surfer.nmr.mgh.harvard.edu/fswiki/BrainstemSubstructures
If you want to segment more specific nuclei, we don’t have a tool capable of 
doing that yet.
Cheers,
/Eugenio


Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 30 Aug 2016, at 17:34, Alshikho, Mohamad J. 
mailto:malshi...@mgh.harvard.edu>> wrote:

Hi Iglesias,
Kindly, we would like to know if there are any methods in Freesurfer that can 
help to segment thatbrain stem nucleus. I mean output the nucleus automatically 
as a small masks, so these small masks can be used in other analyses (e.g. fMRI)

I am thinking of creating masks for these nucleus depending on an atlas. I open 
the T1 image in Fslview and I create the mask for the nucleus of interest. But 
this is so hard, not accurate and time consuming. The reason for my question.
We highly appreciate any suggestion!

Best,
Mohamad






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Re: [Freesurfer] hippo sf segmentation 6.0 dev

2016-08-30 Thread Iglesias, Eugenio
Hi Renata,
In general, mixing’n’matching is not a good idea, since different sequences 
bias the volumes in different directions. Now, if the differences in sequences 
were independent of whether subjects are patients or controls, it wouldn’t be 
*that* bad. But, if patients have different sequences than controls, the 
results are catastrophic because you cannot tell whether detected differences 
are due to anatomy or to the differences in sequences …
- For the T1s, rather than having two groups, you could possibly resample the 
higher-res (0.8) images to 1mm isotropic. But I wonder if this is introducing a 
bias (I’d expect it to be small, but…).
- T2 vs FLAIR: I’d need to see examples to decide. In principle, the one with 
higher contrast and resolution is better ;-)
Cheers,
/Eugenio


Juan Eugenio Iglesias
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 30 Aug 2016, at 17:28, Vaz pandolfo, Renata 
mailto:r...@njit.edu>> wrote:

Dear Eugenio,

I have a couple of questions regarding the hippocampus subfields segmentation 
on the dev FS 6.0 which I hope you could help me with.

We are comparing the volumes of hippocampal subregions of patients and 
controls, and we would like to be as consistent as possible with the input so 
that the output reflects only the differences we expect to see.

The problem is that we have a large number of controls but not all of them have 
the same sequences (T1, T2 or FLAIR) as the patients. So our questions are:

If the T1s from some subjects have a 1x1x1 resolution and others have 
0.8x0.8x0.8 isotropic resolution, do we have to create two groups of controls 
and patients for each sequence? In other words, does the resolution of the T1 
affect the freesurfer segmentation in a way that we can't compare 1x1x1 with 
0.8 x 0.8 x 0.8?

Also, we would like to use T2s or FLAIRs as additional inputs to improve the 
results. Which sequence is preferably recommended? In our case, most controls 
and patients have the same FLAIR sequence, so to keep it consistent we would 
probably use FLAIR if that's worth it.

Finally, we also have different T2s: some isotropic, some anisotropic and 
partial cooverage of the brain, and some anisotropic that are aligned to the 
hippocampus (resolution: 1x1x3, best resolution on coronal slices). Considering 
that they are just additional inputs, do they have to be consistent as well? In 
other words, should we only compare patients and controls that had the same T2 
sequence as additional input and same T1 sequence as main input, or can we "mix 
and match" the additional inputs?

Thank you in advance for your help,

Renata
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Re: [Freesurfer] FLAIR for hippo subfield segmentation with an additional scan

2016-09-05 Thread Iglesias, Eugenio
The same one; just change the input file and the analysis ID

- T2:   recon-all -s mySubject -hippocampal-subfields-T1T2 myT2scan.nii.gz  
T2

- FLAIR: recon-all -s mySubject -hippocampal-subfields-T1T2 myFLAIRscan.nii.gz  
FLAIR

Cheers,

/Eugenio

Juan Eugenio Iglesias
Senior Research Fellow
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 5 Sep 2016, at 15:10, Vaz pandolfo, Renata 
mailto:r...@njit.edu>> wrote:


Dear FS experts,


I have a question about the "segmentation with an additional scan - 
multispectral segmentation"
on the hippocampal sf segmentation, FS dev. 6.0.

For controls on which I had already run recon-all -all, I added the T2 sequence 
with the following
command:

recon-all -s  \
-hippocampal-subfields-T1T2  


Now, if I want to do the same thing with FLAIR as the additional input, which 
flag should I use?

Thank you,

Renata

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Re: [Freesurfer] FLAIR for hippo subfield segmentation with an additional scan

2016-09-05 Thread Iglesias, Eugenio
Sorry, but a 3-channel segmentation is not part of the future FS6.


Juan Eugenio Iglesias
Senior Research Fellow
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 5 Sep 2016, at 15:54, Jovicich, Jorge 
mailto:jorge.jovic...@unitn.it>> wrote:


Hi Eugenio,

just to confirm I understand the currently available options. There are two 
multispectral strategies (MPRAGE + high res 2D T2, or MPRAGE + 3D FLAIR). It 
would be great to see if the combo option improves things even further for the 
subfields (MPRAGE + high res 2D T2 + 3D FLAIR). Is that option at all possible 
with the available FS version or in the works?

Best,

Jorge

On 05/09/2016 16:13, Iglesias, Eugenio wrote:
The same one; just change the input file and the analysis ID

- T2:   recon-all -s mySubject -hippocampal-subfields-T1T2 myT2scan.nii.gz  
T2

- FLAIR: recon-all -s mySubject -hippocampal-subfields-T1T2 myFLAIRscan.nii.gz  
FLAIR

Cheers,

/Eugenio

Juan Eugenio Iglesias
Senior Research Fellow
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 5 Sep 2016, at 15:10, Vaz pandolfo, Renata 
mailto:r...@njit.edu>> wrote:


Dear FS experts,



I have a question about the "segmentation with an additional scan - 
multispectral segmentation"
on the hippocampal sf segmentation, FS dev. 6.0.


For controls on which I had already run recon-all -all, I added the T2 sequence 
with the following
command:


recon-all -s  \
-hippocampal-subfields-T1T2  



Now, if I want to do the same thing with FLAIR as the additional input, which 
flag should I use?

Thank you,


Renata





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The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.



--
Jorge Jovicich, Ph.D.

MR Lab Head
Center for Mind/Brain Sciences
University of Trento,
Via delle Regole, 101
38100 Mattarello (TN)
Italy

Telephone: +39-0461-28 3064
Fax: +39-0461-28-3066
Email: jorge.jovic...@unitn.it<mailto:jorge.jovic...@unitn.it>
MRI Methods Group: http://r.unitn.it/en/cimec/mri
CIMEC: http://www.cimec.unitn.it/

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The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
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but does not contain patient information, please contact the sender and properly
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Re: [Freesurfer] FLAIR for hippo subfield segmentation with an additional scan

2016-09-05 Thread Iglesias, Eugenio
If the T2 is already high-res, and having already the T1, I don’t think that 
the FLAIR would help much.
Cheers,
/E

Juan Eugenio Iglesias
Senior Research Fellow
Translational Imaging Group
University College London
http://www.jeiglesias.com
http://cmictig.cs.ucl.ac.uk/


On 5 Sep 2016, at 16:22, Vaz pandolfo, Renata 
mailto:r...@njit.edu>> wrote:

Dear Jorge,

In my case I am using either T1+T2 or T1+FLAIR.
I had no intention of using all three at once, but now I am also wondering if 
this would be an improvement.

Cheers,

Renata

On Mon, Sep 5, 2016 at 4:54 PM, Jovicich, Jorge 
mailto:jorge.jovic...@unitn.it>> wrote:

Hi Eugenio,

just to confirm I understand the currently available options. There are two 
multispectral strategies (MPRAGE + high res 2D T2, or MPRAGE + 3D FLAIR). It 
would be great to see if the combo option improves things even further for the 
subfields (MPRAGE + high res 2D T2 + 3D FLAIR). Is that option at all possible 
with the available FS version or in the works?

Best,

Jorge

On 05/09/2016 16:13, Iglesias, Eugenio wrote:
The same one; just change the input file and the analysis ID

- T2:   recon-all -s mySubject -hippocampal-subfields-T1T2 myT2scan.nii.gz  
T2

- FLAIR: recon-all -s mySubject -hippocampal-subfields-T1T2 myFLAIRscan.nii.gz  
FLAIR

Cheers,

/Eugenio

Juan Eugenio Iglesias
Senior Research Fellow
Translational Imaging Group
University College London
http://www.jeiglesias.com<http://www.jeiglesias.com/>
http://cmictig.cs.ucl.ac.uk/


On 5 Sep 2016, at 15:10, Vaz pandolfo, Renata 
mailto:r...@njit.edu>> wrote:


Dear FS experts,



I have a question about the "segmentation with an additional scan - 
multispectral segmentation"
on the hippocampal sf segmentation, FS dev. 6.0.


For controls on which I had already run recon-all -all, I added the T2 sequence 
with the following
command:


recon-all -s  \
-hippocampal-subfields-T1T2  



Now, if I want to do the same thing with FLAIR as the additional input, which 
flag should I use?

Thank you,


Renata





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The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.



--
Jorge Jovicich, Ph.D.

MR Lab Head
Center for Mind/Brain Sciences
University of Trento,
Via delle Regole, 101
38100 Mattarello (TN)
Italy

Telephone: +39-0461-28 3064
Fax: +39-0461-28-3066
Email: jorge.jovic...@unitn.it<mailto:jorge.jovic...@unitn.it>
MRI Methods Group: http://r.unitn.it/en/cimec/mri
CIMEC: http://www.cimec.unitn.it/


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The information in this e-mail is intended only for the person to whom it is
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