Dear All,
I have a problem with the structural data for Ranitidine Hydrochloride
(C13H23N4O3S-Cl), a pharmaceutical drug material. It is well known that it
appears in two polymorphous: Form 1 and Form 2. Only the former one has
therapeutic features. The only sructural data that I found in Cambridge
Database are for Form 2 (Ishida & Inoue, Acta Cryst.-C, 1990, 46, 1893. It
is monoclinic, P21/n. Does someone know any structural data for Form 1? I
indexed the pattern with VBTreor (PowderX, Dong, 98) and it seems that Form
1 is also minoclinic, P-type. I am afraid that it will be quite difficult to
solve the structure of Form 1 from X-ray powder data only, but if I have not
any other choice, I can try. Any advise?
Srebri
/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\/\
Dr. Sr. Petrov/PXRD Analyses,
Dept. of Chemistry, U of T,
80 St.George Str., R.417
Toronto ON M5S 3H6, Canada
Tel/Fax: (416)-978-1389.
e-mail: [EMAIL PROTECTED]
