With friction shifters you can run just about anything. For indexed shifting you need to be a bit matchy. The deraillers do not really matter so much. The only issue is that an eight speed chain might be too wide for something like a 10 or 11 speed derailler. As far as shifting all of them basically do whatever the cable instructs. It's the indexed shifter that throws or pulls a certain length of cable to the derailler. With friction, the rider does it by feel and muscle memory. Many riders (esp. cyclotourists and randonneurs) prefer this because it is more trouble free. Indexed shifting is a bit finicky with cable tension (aligning the rear derailler with the rear cogs) and new cables often have to be adjusted as they break-in and stretch a bit. My vote for a crankset would be for a wide range double. Usually people run 46-30 or thereabout. You can get just about the same range of usable gearing and it makes front shifting a breeze. Basically you just throw it all the way either way whenever you need. But I understand the lure of having some huge gear you never use! ;) Excellent bike choice! I love riding fat 650Bs! Oh and at least get some cheap lights to be seen in case you find yourself out there in the dark or even bad weather. Even Knogs or something- Never nothing!
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