Talking direct to uwsgi requires a python helper as Graham mentions.
While I do like the nginx/uwsgi stack, I don't have any problems with
apache/mod_wsgi.  Both are very capable and I find that apache/
mod_wsgi is probably easier to set up and has a much larger support/
installed base. I've deployed applications using both.  In terms of
stability, neither architecture has had any real issues.  In terms of
performance, nginx has a large edge on static files and for this
particular project, that was necessary.  I haven't found the server ->
wsgi -> pylons gateway to be significantly better or worse in either
scenario.

http://www.reddit.com/r/Python/comments/be1q1/benchmark_of_python_web_servers/

is a discussion of the benchmark site listed above with quite a
venomous discussion.

As a personal recommendation, I typically would push someone in the
Apache/mod_wsgi direction, but, there are reasons to chose competing
solutions based on the full stack management.  While it may add
somewhat to the support burden, choosing a solution that isn't widely
deployed will sometimes cause issues.

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