What sort of network stats would be useful to diagnose the problem?  Below is
the output of netstat -s

It looks like data is being transmitted fine up until the point that the
remote server sends a [TCP Window Update] (see packet 1750 below).  At that
point my postfix server doesn't respond and the next packet is a timeout
from the remote server.   All of the data is transferred in about a second
and there is no delay in the tcpdump until right before the timeout.

> No.     Time                       Source                Destination
> Protocol Length Info
>    1750 2016-11-08 17:32:23.323985 DDD.222.3.44          10.10.10.123
> TCP      66     [TCP Window Update] smtp > 47372 [ACK] Seq=264 Ack=6071217
> Win=28960 Len=0 TSval=989115902 TSecr=2863598
>
> Frame 1750: 66 bytes on wire (528 bits), 66 bytes captured (528 bits)
> Ethernet II, Src: Dell_53:eb:0c (00:13:72:53:eb:0c), Dst:
> RealtekU_bd:b1:11
> (52:54:00:bd:b1:11)
> Internet Protocol Version 4, Src: DDD.222.3.44 (DDD.222.3.44), Dst:
> 10.10.10.123 (10.10.10.123)
> Transmission Control Protocol, Src Port: smtp (25), Dst Port: 47372
> (47372),
> Seq: 264, Ack: 6071217, Len: 0 



#netstat -s 

Ip:
    1573140 total packets received
    3130 with invalid addresses
    0 forwarded
    0 incoming packets discarded
    1276252 incoming packets delivered
    649817 requests sent out
Icmp:
    65 ICMP messages received
    3 input ICMP message failed.
    ICMP input histogram:
        timeout in transit: 45
        echo requests: 4
        echo replies: 16
    3522 ICMP messages sent
    0 ICMP messages failed
    ICMP output histogram:
        destination unreachable: 3463
        echo request: 55
        echo replies: 4
IcmpMsg:
        InType0: 16
        InType8: 4
        InType11: 45
        OutType0: 4
        OutType3: 3463
        OutType8: 55
Tcp:
    3867 active connections openings
    20871 passive connection openings
    3 failed connection attempts
    1701 connection resets received
    3 connections established
    729373 segments received
    981408 segments send out
    2196 segments retransmited
    0 bad segments received.
    4880 resets sent
Udp:
    103932 packets received
    3463 packets to unknown port received.
    4 packet receive errors
    97291 packets sent
    InCsumErrors: 4
UdpLite:
TcpExt:
    75 invalid SYN cookies received
    14488 TCP sockets finished time wait in fast timer
    10723 delayed acks sent
    3 delayed acks further delayed because of locked socket
    67 packets directly queued to recvmsg prequeue.
    2662149 bytes directly in process context from backlog
    7208 bytes directly received in process context from prequeue
    255804 packet headers predicted
    1888 packets header predicted and directly queued to user
    130231 acknowledgments not containing data payload received
    225519 predicted acknowledgments
    15 times recovered from packet loss by selective acknowledgements
    133 congestion windows recovered without slow start after partial ack
    32 fast retransmits
    4 forward retransmits
    267 other TCP timeouts
    TCPLossProbes: 1547
    TCPLossProbeRecovery: 360
    1633 DSACKs received
    1746 connections reset due to unexpected data
    395 connections reset due to early user close
    36 connections aborted due to timeout
    TCPDSACKIgnoredNoUndo: 1456
    TCPSackShifted: 237
    TCPSackMerged: 69
    TCPSackShiftFallback: 189
    IPReversePathFilter: 7
    TCPRcvCoalesce: 57204
    TCPAutoCorking: 4
    TCPSynRetrans: 196
    TCPOrigDataSent: 731195
IpExt:
    InBcastPkts: 447052
    InOctets: 703894455
    OutOctets: 858029660
    InBcastOctets: 48518221
    InNoECTPkts: 1573150




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