I have installed postfix mail server in ubuntu machine. I am facing some
issues with the mail sending to other domain mail servers (Google, Yahoo,
Outlook...). I am using virtual domain to send the email using SMTP of the
mail server (say n...@xyz.server.com)

When I try to send multiple emails through postfix SMTP, its failed to send
the mails. Sometimes they get successfully sent and sometimes its fail.
However, if i try to send the same using the relayhost, its working without
any issues. [I could not use the relayhost (say gmail relay server), since
it wont provide the option to set sender email id as my own and it has its
own limits (500 per day something like that)]

Following error mesages available in mail.log file.

Jan 14 11:40:25 server1 postfix/smtp[4776]: connect to
gmail-smtp-in.l.google.com[2607:f8b0:400e:c02::1a]:25: Network is
unreachable
Jan 14 11:41:25 server1 postfix/smtp[4776]: 6F11361C56: to=<x...@gmail.com>,
relay=none, delay=61, delays=0.71/0/60/0, dsn=4.4.1, status=deferred
(connect to alt2.gmail-smtp-in.l.google.com[2607:f8b0:4002:c09::1b]:25:
*Network is unreachable*)

Jan 14 07:33:42 server1 postfix/smtp[4780]: 1BE9261CF6:
to=<x...@outlook.com>, relay=none, delay=151, delays=0.68/0/150/0,
dsn=4.4.1, status=deferred (connect to mx4.hotmail.com[207.46.8.199]:25:
*Connection timed out*)

I have tried to change the "inet_protocols" value to "ipv4" in the file
"/etc/postfix/main.cf" and restarted postfix server. But it wont fix the
issue.

Note:

* Mailserver hosted in Amazon EC2 instance with a static IP address (connect
to internet, and all traffic ports are opened for inbound and outbound in
security groups).
* Telnet to the port 25 of the specific smtp server is working randomly
(sometimes works and sometimes not).
* Ping to the SMTP server is always successfull(Telnet to port 25 fails most
of the time).
* I am using self signed certicate in my Mail server.

Can any one let us know, how to fix this issue. Is this something we need to
look into our mail server configuration ?



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