[NMusers] Time 'T' in $Error

[Katrin Volz]

Dear NMuser,

 

I would like to model a PD effect using a function which includes continuous
time ‘ T ’. 

 

The PD Effect is coded in $Error.

In general like this:

$ERROR

MyFunction = xxx + T

PDEffect = Basline * MyFunction

 

But ‘T’ cannot be used in $Error.

 

I tried to code the function with ‘T’ in $DES and rename it to use it in
$ERROR:

 

$DES

MyFunction = xxx + T

$ERROR

MyNewFunction = MyFunction

PDEffect = Baseline * MyNewFunction

 

but it didn’t worked (to rename was not permitted by NONMEM).

 

Does anyone of you has an idea how to solve this problem?

 

Thanks and best regards.

Katrin

 

 

 

Anke-Katrin Volz

PhD Student 

Saarland University

Clinical Pharmacy

Campus C2 2 | Room 0.31

D- 66123 Saarbrücken

 

mail ankekatrin.v...@uni-saarland.de

fon +49 [0]681 302 22 84

fax +49 [0]681 302 70 258

www.clinicalpharmacy.me