Now that there is Alphafold, perhaps one could use the ribosome to build 
scaffolding for 3-d semiconductors? That would be another ten-fold reduction in 
feature size compared to lithography. 

From: Friam <friam-boun...@redfish.com> on behalf of Jon Zingale 
<jonzing...@gmail.com>
Date: Tuesday, February 25, 2025 at 1:34 PM
To: The Friday Morning Applied Complexity Coffee Group <friam@redfish.com>
Subject: Re: [FRIAM] free will 

"What is special, if anything, about organisms that have nervous systems built 
on organic chemistry that could enable something else?" 



For the most part, I agree with you. Why shouldn't there be silicon 
architectures that get arbitrarily close to the agential quality exhibited by 
life. On the other hand, I do not yet see anything designed by us that comes 
close to the complex sophistication of life at the finest scales. In part this 
seems like a design problem in that we design our chips to function in exact 
and narrow ways. We engineer against exaptation, much less do we design for 
anything like Levin style polycomputing. As far as I can tell, nothing in 
chemistry is solely a camera, microphone, or chemical sensor. The usefulness of 
molecules in given contexts determine function. This matters to me exactly 
because enumerating/coding the affordances via modern techniques would almost 
certainly lead to an explosion in computational complexity, monstrous scaling 
mismatches or worse. I suspect that the computing architectures we have already 
found, while impressive and hard won, are still far from what we would need to 
do meaningful massive multi-channel and heterogeneous information processing at 
the density we see in life. 



This is all to say, I doubt we do anything particularly "special", but I would 
bet that the sun will burn out long before we have agential computers as 
interesting as life. Regarding free will, I have nothing new to say that we 
haven't already hashed many times before. 



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