No, I don't think so.
On 5/14/2025 11:51 AM, Arianna Menardi wrote:
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Thank you Stefano!
Just an additional curiosity, is there any function within Freesurfer
that you think could be used to map and quantify microbleeds in SWI data?
Thanks for the help,
Arianna
Il giorno mer 14 mag 2025 alle ore 17:26 Stefano Cerri
<ste.45....@gmail.com> ha scritto:
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Hi Arianna,
1) Yes. Please note that the method was tuned and mostly tested on
MS patients.
2) These two versions of SAMSEG model WMH/ WM lesions differently
and cannot be directly compared. The basic SAMSEG is not designed
for accurate WMH or WM lesion estimation. Note that you can use
the lesion version of SAMSEG on scans without lesions (see Fig. 6
here
<https://secure-web.cisco.com/1KM7GJ1i4uKDVvBOOHjfxLxbNpEbDV37ju32_ri0-iGtre9ZQKasYmqnwK6bi5vzt5-BaRS02ywgcOcI--IezHyHTAKt807vpLrXUZvO33iKmYOL0EeUkqkVhKXj38poEFY9bY4Djm69SgNrHqC2TpJRpU5OQUybXs5s7nPnXPv0ArkvG_YpXaiip_cs58dLk8TygUTgVuRtW8x9gYHo_BSTpTQs6pwsWwQ2nel-ejGeDe1nkcKTJcqBaT8vZrbLqyVpzVwZRXQDIXUhOjCyNPkbtTJdnT8BSGUjOyXcMp0Etejbfjh9bThJhaEK0tzEhXSLDLIgxCcSmrxk53keXlg/https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Farticle%2Fpii%2FS1053811920309563>).
3) Yes. Note that SWI data might not add valuable information to
the lesion and whole-brain segmentation task. My suggestion is to
visually inspect a couple of subjects with and without SWI data.
Stefano
Sent on behalf of Arianna Menardi:
----
Dear Experts,
I'm trying to quantify the volume of some white matter lesions in
an elderly group. I have tried using both Samseg cross-sectional,
as well as Samseg for MS lesions.
I am new to the approach so I have 3 main questions:
1. Can I use Samseg for MS lesions even if my patients present WM
lesions but are not MS patients?
2. the estimated values of WM-hypointensities derived from the
basic version of Samseg are almost half in size compared to the
output 'Lesions" of Samseg specific for MS lesions. What is hence
the difference between the two approaches that could explain such
a big difference in the output?
3. Can I use Samseg combining T1w, FLAIR and SWI data? Or the
algorithms are not suited for SWI images?
Thank you for your help,
Arianna
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